GTPase NRas Protein (NRAS) (AA 1-186)

N° du produit ABIN935092

Protéine Recombinant GTPase NRas exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour GTPase NRas Protein (NRAS) (AA 1-186) (ABIN935092)

Antigène: GTPase NRas (NRAS)

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Pureté: > 95 % pure

Détail du produit

Attributs du protein: AA 1-186

Séquence: MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET CLLDILDTAG QEEYSAMRDQ YMRTGEGFLC VFAINNSKSF ADINLYREQI KRVKDSDDVP MVLVGNKCDL PTRTVDTKQA HELAKSYGIP FIETSAKTRQ GVEDAFYTLV REIRQYRMKK LNSSDDGTQG CMGLPC

Attributs du produit: Purified recombinant Human NRAS protein
Expression System: E.coli

Information d'application

Indications d'application: NRAS protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Supplied as a liquid in 20 mM Tris-HCl buffer, pH 7.5, containing 100 mM NaCl, 10 % glycerol.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: RT/-20 °C

Stockage commentaire: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Détail du antigène

Antigène: GTPase NRas (NRAS)

Autre désignation: NRAS

Sujet: Neuroblastoma RAS viral (v-ras) oncogene homolog, also known as NRAS, is a member of the RAS gene family. NRAS is an oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. The encoded protein, which has intrinsic GTPase activity, is activated to a GTP-bound form by a GTPase activating protein and inactivated to a GDP-bound form by a guanine nucleotide-exchange factor. Recombinant human NRAS was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: N ras protein part 4 protein, HRAS1 protein, v ras neuroblastoma RAS viral oncogene homolog, NS6 protein, OTTHUMP00000013879 protein, Neuroblastoma RAS viral (v ras) oncogene homolog protein, ALPS4 protein, GTPase NRas protein, AV095280 protein, N ras protein, Transforming protein N Ras protein, N-ras protein, NRAS1 protein, Neuroblastoma RAS viral (v-ras) oncogene homolog OTTMUSP00000023521 protein

Poids moléculaire: 20.8 kDa (186 AA)

Pathways: Signalisation p53, Signalisation MAPK, Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling