IL-11 Protéine
Aperçu rapide pour IL-11 Protéine (ABIN935575)
Antigène
Voir toutes IL-11 (IL11) ProtéinesType de proteíne
Activité biologique
Origine
Source
Pureté
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Séquence
- MPGPPAGSPR VSSDPRADLD SAVLLTRSLL ADTRQLAAQM RDKFPADGDH SLDSLPTLAM SAGTLGSLQL PGVLTRLRVD LMSYLRHVQW LRRAGGPSLK TLEPELGALQ ARLERLLRRL QLLMSRLALP QAAPDQPVIP LGPPASAWGS IRAAHAILGG LHLTLDWAVR GLLLLKTRL
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Attributs du produit
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Purified recombinant Mouse IL11 protein
Expression System: E.coli
Bioactivity: The ED50 was determined by the dose-dependent stimulation of the proliferation of Mouse T11 cells is ? 2.0 ng/mL, corresponding to a specific activity of ? 5 x 10^5 units/mg. -
niveau d'endotoxine
- < 0.1 ng per µg (1 EU/µg).
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Supplied as a lyophilized powder.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- RT/-20 °C
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- IL-11 (IL11) (Interleukin 11 (IL11))
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Autre désignation
- IL11
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Sujet
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IL11 is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts. It is expressed in a wide variety of tissues including thymus, lung, bone, connective tissue and central nervous system. IL11 plays an important regulatory role in hematopoiesis by stimulating growth of myeloid, erythroid and megakaryocyte progenitor cells. It also regulates bone metabolism, inhibits production of proinflammatory cytokines and protects against gastromucosal injury.
Alternative Names: Interleukin 11 protein, AGIF protein, IL 11 protein, IL-11 protein, IL-11 protein, IL11, IL-11, Adipogenesis inhibitory factor protein, IL 11 -
Poids moléculaire
- 19.1 kDa
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Pathways
- Signalistation JAK/STAT, Negative Regulation of Hormone Secretion
Antigène
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