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This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats. Alternatively spliced transcript variants have been described for this locus.
F-box and leucine-rich repeat protein 5 , F-box/LRR-repeat protein 5 , F-box/LRR-repeat protein 5-like , F-box protein FBL4/FBL5 , F-box protein FBL5 , p45SKP2-like protein
GENE ID | SPECIES |
---|---|
479085 | Canis lupus familiaris |
100511143 | Sus scrofa |
422829 | Gallus gallus |
380440 | Xenopus laevis |
432131 | Xenopus laevis |
461125 | Pan troglodytes |
496483 | Xenopus (Silurana) tropicalis |
100012405 | Monodelphis domestica |
100074228 | Ornithorhynchus anatinus |
100173556 | Pongo abelii |
100351566 | Oryctolagus cuniculus |
100388303 | Callithrix jacchus |
100605502 | Nomascus leucogenys |
26234 | Homo sapiens |
519695 | Bos taurus |
242960 | Mus musculus |
305424 | Rattus norvegicus |
322181 | Danio rerio |
101106171 | Ovis aries |