IL-6 anticorps (Biotin)
Aperçu rapide pour IL-6 anticorps (Biotin) (ABIN115883)
Antigène
Voir toutes IL-6 (IL6) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- Detects murine IL-6.
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Purification
- Affinity chromatography.
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Immunogène
- Highly pure (>98%) recombinant mIL-6
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anti-Interleukin 6 (IL6) (AA 111-150) antibody
IL6 Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache) WB, ELISA, FACS, IF (p), IHC (p), IF (cc), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Interleukin 6 (IL6) antibodyIL6 Reactivité: Humain ELISA, FACS, Func, ELISpot Hôte: Souris Monoclonal B-E8 unconjugated
anti-Interleukin 6 (IL6) (AA 21-211) antibodyIL6 Reactivité: Rat WB, IHC, IP, ICC Hôte: Souris Monoclonal C4 unconjugated
anti-Interleukin 6 (IL6) (AA 27-212) antibodyIL6 Reactivité: Macaque rhésus WB, IHC, IP, ICC Hôte: Souris Monoclonal 18# unconjugated
anti-Interleukin 6 (IL6) (AA 21-211) antibodyIL6 Reactivité: Rat WB, IHC, IP, IF/ICC Hôte: Souris Monoclonal unconjugated
anti-Interleukin 6 (IL6) (AA 27-241) antibodyIL6 Reactivité: Lapin WB, IHC, IP, ICC Hôte: Souris Monoclonal C506 unconjugated
anti-Interleukin 6 (IL6) (AA 101-150) antibodyIL6 Reactivité: Souris, Rat WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Interleukin 6 (IL6) (AA 25-211) antibodyIL6 Reactivité: Souris WB, ELISA Hôte: Lapin Polyclonal unconjugated
anti-Interleukin 6 (IL6) (AA 21-211) antibodyIL6 Reactivité: Rat WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Interleukin 6 (IL6) (AA 29-212) antibodyIL6 Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated
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Indications d'application
- ELISA: (Direct): To detect mIL-6 by direct ELISA (using 100 μL/well antibody solution) aconcentration of 0.25-1.0 μg/mL of this antibody is required. This biotinylated polyclonalantibody, in conjunction with compatible secondary reagents, allows the detection of atleast 0.2-0.4 ng/well of recombinant mIL-6. (Sandwich): To detect mIL-6 by sandwich ELISA (using 100 μL/well antibody solution) aconcentration of 0.25 - 1.0 μg/mL of this antibody is required. This biotinylated polyclonalantibody, in conjunction with Polyclonal Anti-Murine IL-6 (PP012P) as a capture antibody,allows the detection of at least 0.2-0.4 ng/well of recombinant mIL-6.
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Restrictions
- For Research Use only
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Reconstitution
- Restore in sterile PBS containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL.
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Buffer
- PBS, pH 7.2 without preservatives.
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Agent conservateur
- Without preservative
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Stock
- 4 °C
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- IL-6 (IL6) (Interleukin 6 (IL6))
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Autre désignation
- Interleukin-6 (IL6)
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Sujet
- Interleukin 6 (IL6) is a multifunctional 24 kDa protein originally discovered in the medium of RNA stimulated fibroblastoid cells. It is upregulated by IL1, TNF, PDGF, IFN beta, TNF alpha, NGF, IL17 and downregulated by glucocorticoids IL4, TGF beta. IL6 appears to be directly involved in the responses that occur after infection and cellular injury, and it may prove to be as important as IL1 and TNF alpha in regulating the acute phase response. IL6 has also been implicated in regulating adipose mass. IL6 is reported to be produced by fibroblasts, activated T cells, activated monocytes or macrophages and endothelial cells. It acts upon a variety of cells including fibroblasts, myeloid progenitor cells, T cells, B cells and hepatocytes. In addition, IL6 appears to interact with IL2 in the proliferation of T lymphocytes. IL6 potentiates the proliferative effect of IL3 on multipotential hematopoietic progenitors.Synonyms: B-cell stimulatory factor 2, BSF-2, CDF, CTL differentiation factor, Hybridoma growth factor, IFNB2, IL-6, Interferon beta-2
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ID gène
- 16193
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NCBI Accession
- NP_112445
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UniProt
- P08505
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Pathways
- Signalisation TLR, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
Antigène
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