anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) Anticorps

The membrane-associated protein encoded by ABCB1B is a member of the superfamily of ATP-binding cassette (ABC) transporters. De plus, nous expédions ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Protéines (11) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
ABCB1B 5243 P08183
ABCB1B 18669 P06795
ABCB1B 24646  
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Top anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Anticorps sur anticorps-enligne.fr

Showing 10 out of 31 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué FACS, IF (p), IHC (p) Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-MDR1/p-GP/CD243 Polyclonal Antibody (ABIN670161), Unconjugated 1:200 at 1:200, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-MDR1/p-GP/CD243 Polyclonal Antibody , Unconjugated 1:200 at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Connectez-vous pour afficher 9 to 12 Days
315,94 €
Détails
Humain Lapin Inconjugué ICC, IF, IHC (p) Immunofluorescence analysis of mouse kidney tissue using anti-MDR1 (dilution of primary antibody - 1:1000) Immunohistochemical staining of paraffin embedded mouse kidney tissue using anti-MDR1 (primary antibody at 1:1000) 100 μg Connectez-vous pour afficher 7 to 12 Days
295,90 €
Détails
Humain Souris Inconjugué IF, IP, WB   100 μL Connectez-vous pour afficher 12 Days
327,38 €
Détails
Humain Souris Inconjugué FACS, IF, IHC, WB   500 μL Connectez-vous pour afficher 15 to 21 Days
704,49 €
Détails
Humain Souris Inconjugué IC, IHC, WB   100 μg Connectez-vous pour afficher 15 to 21 Days
526,53 €
Détails
Hamster Souris Inconjugué FACS, IF, IHC, WB   500 μL Connectez-vous pour afficher 15 to 21 Days
676,73 €
Détails
Humain Lapin Inconjugué IHC   50 μg Connectez-vous pour afficher 15 to 21 Days
743,68 €
Détails
Humain Souris Inconjugué FACS, IHC, WB   100 μL Connectez-vous pour afficher 15 to 21 Days
743,68 €
Détails
Humain Souris Inconjugué IC, FACS, IHC, WB   250 μg Connectez-vous pour afficher 15 to 21 Days
830,20 €
Détails
Humain Rat Inconjugué IC, FACS, IHC, WB   125 μg Connectez-vous pour afficher 15 to 21 Days
854,70 €
Détails

ABCB1B Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Anticorps mieux référencés

  1. Human Polyclonal ABCB1B Primary Antibody pour FACS, IF (p) - ABIN670161 : Hu, Peng, Li: The expression and significance of P-glycoprotein, lung resistance protein and multidrug resistance-associated protein in gastric cancer. dans Journal of experimental & clinical cancer research : CR 2009 (PubMed)
    Show all 2 references for 670161

Plus d’anticorps contre ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B partenaires d’interaction

Human ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) interaction partners

  1. Meta-analysis found no evidence for ABCB1 (Montrer ABCB1 Anticorps) C3435T and C1236T polymorphisms as risk factors for pediatric Acute Lymphoblastic Leukemia.

  2. ABCB1 (Montrer ABCB1 Anticorps) gene polymorphisms in association with others risk factors contribute to anti-TB drug resistance, mainly ethambutol.

  3. For the first time, we demonstrated that MDR1 (Montrer TBC1D9 Anticorps) rs1128503 polymorphisms were associated with systemic lupus erythematosus susceptibility in Chinese Guangxi population.

  4. multiple pathways, including MMP9 (Montrer MMP9 Anticorps) cleavage and ubiquitinylation, mediated P-gp (Montrer ABCB4 Anticorps) downmodulation.

  5. We also determined the effect of Pygo2 on the sensitivity of breast tumors resistant to doxorubicin in a mouse model. Finally, RNA samples from 64 paired patient tumors (before and after chemotherapy) highly and significantly overexpressed Pygo2 and/or MDR1 after treatment, thus underlining a pivotal role for the Pygo2-mediated Wnt/b-catenin pathway in the clinical chemoresistance of breast cancer.

  6. We did not find any relationship between the methylation levels of the ABCB1 (Montrer ABCB1 Anticorps) promoter and clopidogrel resistance (CR). In conclusions, our study indicated that ABCB1 (Montrer ABCB1 Anticorps) polymorphisms might be useful in further evaluating the pathogenesis of CR.

  7. A subset of virus-specific CD161 (Montrer KLRB1 Anticorps)(+) T cells selectively express the multidrug transporter MDR1 (Montrer TBC1D9 Anticorps) and are resistant to chemotherapy in acute myeloid leukemia (Montrer BCL11A Anticorps).

  8. Primary CD4 (Montrer CD4 Anticorps)+P-gphigh T cells eliminate intracellular raltegravir more readily than P-gplow cells and HIV-1 viraemia correlates with P-gp (Montrer ABCB4 Anticorps) overall activity; specific CD4 (Montrer CD4 Anticorps)+P-gphigh T cell subsets could facilitate the persistence of viral replication in vivo and ultimately promote the appearance of drug resistance

  9. We observed an association between ABCB1 (Montrer ABCB1 Anticorps) 3435 T/T and lower grade of toxicities (p=0.05) in patients receiving taxanes for breast cancer. No other associations were found for CYP (Montrer PPIG Anticorps) 3A4 *1B, 3A5*3 and ABCB1 (Montrer ABCB1 Anticorps) C1236T.

  10. that residual SWI (Montrer SMARCA1 Anticorps)/SNF (Montrer SNRPA Anticorps) complexes lacking SMARCB1 (Montrer SMARCB1 Anticorps) are vital determinants of drug sensitivity, not just to TOP2A (Montrer TOP2A Anticorps)-targeted agents, but to the much broader range of cancer drugs effluxed by ABCB1 (Montrer ABCB1 Anticorps).

Mouse (Murine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) interaction partners

  1. the high-affinity site of P-glycoprotein is inaccessible because of either a conformational change or binding of detergent at the binding site in a detergent micelle environment; ligands bind to a low-affinity site, resulting in altered modulation of P-gp (Montrer ABCB4 Anticorps) ATPase (Montrer DNAH8 Anticorps) activity

  2. Data suggest that ATP binding to Abcb1b/P-glycoprotein (Pgp) in liposomes exhibits cooperativity with verapamil (a cardiovascular/antiarrhythmia drug); cooperativity between verapamil and a nonhydrolyzable ATP analog (AMPPNP) leads to distinct global conformational changes in Abcb1b/Pgp.

  3. Chrysosplenetin inhibited P-gp (Montrer ABCB4 Anticorps) activity and reverse the up-regulated P-gp (Montrer ABCB4 Anticorps) and MDR1 (Montrer ABCB4 Anticorps) levels induced by artemisinin.

  4. Tamsulosin and tolterodine with P-gp (Montrer ABCB4 Anticorps) gene expression and activity in an enantiomer-specific way.

  5. Pgp (Montrer ABCB4 Anticorps)-coupled ATPase (Montrer DNAH8 Anticorps) activity kinetics measured with a range of verapamil and digoxin concentrations fit well to a DDI model encompassing non-competitive and competitive inhibition of digoxin by verapamil.

  6. Data show that human transgenic mutant huntingtin (Montrer HTT Anticorps) (mHtt) aggregation might be regulated by multidrug resistance protein 1 (MDR1 (Montrer ABCB4 Anticorps)) which suggests that MDR1 (Montrer ABCB4 Anticorps) might be a potential therapeutic target for Huntington's disease.

  7. In vitro and in vivo downregulation of the ATP binding cassette transporter (Montrer ABCC3 Anticorps) B1 by the HMG-CoA reductase (Montrer HMGCR Anticorps) inhibitor simvastatin

  8. Efficient chemoprotection of CDD (Montrer CDA Anticorps) and MDR1 (Montrer ABCB4 Anticorps) transduced hematopoietic 32D as well as primary lin(-) cells was proven in the context of Ara (Montrer FOXC1 Anticorps)-C and anthracycline application

  9. These study data have facilitated understanding of the molecular mechanisms of neurotoxicosis in ABCB1 (Montrer ABCB1 Anticorps)-1Delta mutant mice following exposure to various P-gp (Montrer ABCB4 Anticorps) substrates.

  10. Data indicate that the brain penetration of ABT-888 in both Abcb1a (Montrer ABCB4 Anticorps)/1b-/- and Abcb1a (Montrer ABCB4 Anticorps)/1b-/-;Abcg2 (Montrer ABCG2 Anticorps)-/- mice was significantly higher than in wild-type mice.

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) profil antigène

Profil protéine

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

Gene names and symbols associated with ABCB1B

  • ATP-binding cassette, sub-family B (MDR/TAP), member 1 (ABCB1) anticorps
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) anticorps
  • ATP-binding cassette, subfamily B (MDR/TAP), member 1B (Abcb1b) anticorps
  • ABC20 anticorps
  • Abcb1 anticorps
  • CD243 anticorps
  • CLCS anticorps
  • GP170 anticorps
  • mdr anticorps
  • Mdr1 anticorps
  • Mdr1b anticorps
  • P-GP anticorps
  • Pgy-1 anticorps
  • Pgy1 anticorps

Protein level used designations for ABCB1B

P-glycoprotein 1 , colchicin sensitivity , doxorubicin resistance , multidrug resistance protein 1 , ATP-binding cassette sub-family B member 1 , P glycoprotein 1 , multidrug resistance protein 1B , ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1B , ATP-binding cassette, subfamily B, member 1B , P-glycoprotein/multidrug resistance 1

GENE ID SPECIES
5243 Homo sapiens
18669 Mus musculus
24646 Rattus norvegicus
Fournisseurs de qualité sélectionnés pour anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) Anticorps
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