anticorps PAR-3, anticorps PAR3, anticorps par3, anticorps Cf-2, anticorps Cf2, anticorps FII, anticorps thrombin, anticorps F730031A08, anticorps f2, anticorps f2rl2, anticorps coagulation factor II thrombin receptor like 2, anticorps coagulation factor II (thrombin) receptor-like 2, anticorps coagulation factor II, anticorps coagulation factor II, thrombin, anticorps coagulation factor II, thrombin L homeolog, anticorps coagulation factor II (thrombin) receptor-like 2 L homeolog, anticorps F2RL2, anticorps f2rl2, anticorps F2, anticorps F2rl2, anticorps f2.L, anticorps f2rl2.L
Sujet
Coagulation factor II (thrombin) receptor-like 2 (F2RL2) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL2 is also a member of the protease-activated receptor family and activated by thrombin. F2RL2 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL2 is a cofactor for F2RL3 activation by thrombin. It mediates thrombin-triggered phosphoinositide hydrolysis and is expressed in a variety of tissues.Synonyms: Coagulation factor II receptor-like 2, PAR-3, PAR3, Proteinase-activated receptor 3, Thrombin receptor-like 2