Aperçu des produits pour anti-NRF2 (NFE2L2) Anticorps

Full name:
anti-Nuclear Factor (erythroid-Derived 2)-Like 2 Anticorps (NFE2L2)
Chez www.anticorps-enligne.fr sont 212 Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) Anticorps de 26 de différents fournisseurs disponibles. De plus, nous expédions NRF2 Kits (50) et NRF2 Protéines (10) et beaucoup plus de produits pour cette protéine. Un total de 282 NRF2 produits sont actuellement listés.
Synonymes:
AI194320, NF-E2R2, nfe2l2, NRF2, wu:fc15g09, wu:fj67e03

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anti-NRF2 Anticorps mieux référencés

  1. Human Polyclonal NRF2 Primary Antibody pour IHC (fro), IF (p) - ABIN676673 : Lee, Hsu, Chang, Kuo, Hsu, Pan: Ankaflavin: a natural novel PPAR? agonist upregulates Nrf2 to attenuate methylglyoxal-induced diabetes in vivo. dans Free radical biology & medicine 2012 (PubMed)
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  2. Human Polyclonal NRF2 Primary Antibody pour IF (p), IHC (p) - ABIN737271 : Wang, Fang, Huang, Chen, Fan, Wang: The chronic effects of low lead level on the expressions of Nrf2 and Mrp1 of the testes in the rats. dans Environmental toxicology and pharmacology 2013 (PubMed)
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  3. Human Polyclonal NRF2 Primary Antibody pour ChIP, ICC - ABIN442777 : Sullivan, Martinez-Garcia, Nguyen, Mullen, Dufour, Sudarshan, Licht, Deberardinis, Chandel: The proto-oncometabolite fumarate binds glutathione to amplify ROS-dependent signaling. dans Molecular cell 2013 (PubMed)
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  4. Human Polyclonal NRF2 Primary Antibody pour IHC (p), WB - ABIN3043888 : Wang, Du, Duan, Guo, Sun, Liu: Inhibiting heme oxygenase-1 attenuates rat liver fibrosis by removing iron accumulation. dans World journal of gastroenterology : WJG 2013 (PubMed)
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  5. Human Polyclonal NRF2 Primary Antibody pour IHC, ELISA - ABIN1584873 : Bagul, Middela, Matapally, Padiya, Bastia, Madhusudana, Reddy, Chakravarty, Banerjee: Attenuation of insulin resistance, metabolic syndrome and hepatic oxidative stress by resveratrol in fructose-fed rats. dans Pharmacological research : the official journal of the Italian Pharmacological Society 2012 (PubMed)
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  6. Human Polyclonal NRF2 Primary Antibody pour EIA, WB - ABIN359515 : Zhao, Sun, Zhang, Strong, Dash, Kan, Grotta, Aronowski: Transcription factor Nrf2 protects the brain from damage produced by intracerebral hemorrhage. dans Stroke; a journal of cerebral circulation 2007 (PubMed)
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  7. Human Polyclonal NRF2 Primary Antibody pour EIA, WB - ABIN359516 : Li, Jang, Na, Cha, Surh: Carbon monoxide produced by heme oxygenase-1 in response to nitrosative stress induces expression of glutamate-cysteine ligase in PC12 cells via activation of phosphatidylinositol 3-kinase and Nrf2 signaling. dans The Journal of biological chemistry 2007 (PubMed)
    Show all 2 references for 359516

  8. Cow (Bovine) Polyclonal NRF2 Primary Antibody pour WB - ABIN2780749 : Padmanabhan, Tong, Ohta, Nakamura, Scharlock, Ohtsuji, Kang, Kobayashi, Yokoyama, Yamamoto: Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer. dans Molecular cell 2006 (PubMed)

  9. Human Monoclonal NRF2 Primary Antibody pour IHC, ELISA - ABIN1724931 : Sandford, Malhotra, Boezen, Siedlinski, Postma, Wong, Akhabir, He, Connett, Anthonisen, Paré, Biswal: NFE2L2 pathway polymorphisms and lung function decline in chronic obstructive pulmonary disease. dans Physiological genomics 2012 (PubMed)

Plus d’anticorps contre NRF2 partenaires d’interaction

Zebrafish Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) interaction partners

  1. These data suggest that EC from the Tripterygium wilfordii stem extract could diminish tau-GFP-induced neuronal death through the activation of Nrf2.

  2. we concluded that Nrf2 plays a fundamental and conserved role in protection against acute sodium arsenite toxicity

  3. Coptisine exerted its antioxidant activity against AAPH-induced toxicity involving in activating Akt (Montrer AKT1 Anticorps) and JNK (Montrer MAPK8 Anticorps)/Nrf2/NQO1 (Montrer NQO1 Anticorps) pathway.

  4. Bach1 (Montrer BACH1 Anticorps) regulates the liver specificity and transience of the Nrf2a-dependent induction of hmox1a and that heme mediates this regulation through Bach1 (Montrer BACH1 Anticorps) inhibition based on its level in each tissue.

  5. The Bach1b-MafK heterodimer represses the zymogen promoters, whereas the Nrf2a-MafK heterodimer activates them.

  6. The expression of nrf (Montrer NRF1 Anticorps) genes varies temporally throughout development and nrf (Montrer NRF1 Anticorps) genes are induced following a pro-oxidant exposure and are potentially cross-regulated by gene family members Nrf2a and Nrf2b (Montrer GABPb Anticorps).

  7. oxidative stress is an important mechanism of Cd-mediated injury in the zebrafish olfactory system; the Nrf2 pathway plays a protective role against cellular oxidative damage and is important in maintaining zebrafish olfactory function.

  8. results revealed that nrf2 mutant zebrafish are viable and fertile but show an increased susceptibility to oxidative stress and electrophiles

  9. compared the tissue-specific expression of several Nrf2 target genes in zebrafish larvae; Tissue-restricted induction was observed in the nose, gill, and/or liver for seven genes in response to Nrf2-activating compounds

  10. Nrf2 is protective against PFOS-induced oxidative stress in zebrafish larvae.

Cow (Bovine) Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) interaction partners

  1. These findings suggest that bronchiolar epithelial cells and macrophages up-regulate Nrf2 expression early in the course of infection, which results in increased expression of HO-1 (Montrer HMOX1 Anticorps) within these cells.

  2. the survival and developmental competence of embryos cultured under oxidative stress are associated with activity of the NRF2-mediated oxidative stress response pathway during bovine pre-implantation embryo development.

  3. investigation of molecular mechanisms of microvascular complications in diabetes/hyperglycemia: Nrf2 is involved in regulation of HO-1 (Montrer HMOX1 Anticorps) gene expression in aortic endothelial cells by advanced glycation end products

Pig (Porcine) Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) interaction partners

  1. Lack of Nrf2 enhances susceptibility to mycotoxin-induced kidney disease.

  2. The effects of ochratoxin A on the nuclear translocation and transactivation of the transcription factor Nrf2 as well as mRNA levels of Nrf2 target genes are reported.

Human Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) interaction partners

  1. inflammatory cytokines promoted Nrf2 (Montrer GABPA Anticorps) nuclear translocation in psoriatic epidermis, which led to elevated expression of K6, K16 (Montrer KRT16 Anticorps), and K17 (Montrer KRT17 Anticorps), thus promoting keratinocyte proliferation and contributing to the pathogenesis of psoriasis.

  2. The two compounds were shown to induce apoptosis and inhibit the Nrf2 (Montrer GABPA Anticorps)/ARE signaling pathway in Hep3B cells.

  3. Reduced mRNA expression of NFE2L2 is associated with breast cancer.

  4. Data (including data from studies using cells from knockout mice) confirm that the NRF2 (Montrer GABPA Anticorps)/HMOX1 (Montrer HMOX1 Anticorps) axis is a critical pathway in the hyperglycemic-mediated dysregulation and inflammatory features of chondrocytes in type 2 diabetes-associated osteoarthritis. (NRF2 (Montrer GABPA Anticorps) = nuclear factor [erythroid-derived 2]-like 2 protein; HMOX1 (Montrer HMOX1 Anticorps) = heme oxygenase (Montrer HMOX1 Anticorps) [decycling] 1)

  5. This study demonstrates that Nrf2 (Montrer GABPA Anticorps) could be an ideal druggable target in AML (Montrer RUNX1 Anticorps), more so to the drugs that function through ROS (Montrer ROS1 Anticorps), suggesting the possibility of using Nrf2 (Montrer GABPA Anticorps) inhibitors in combination with chemotherapeutic agents to modulate drug resistance in AML (Montrer RUNX1 Anticorps).

  6. -rich DNA causes a prolonged increase in mRNA levels of NF-kB and NRF2 (Montrer GABPA Anticorps) which lasts 48 and 24 h, respectively.

  7. examination of plant (Montrer GABPA Anticorps)ar skin b (Montrer KRT16 Anticorps)iopsies from individuals with pachyonychia congenita confirmed the presence of (Montrer GABPA Anticorps) high levels of hypophosphorylated NRF2 in lesional tissue

  8. SIRT2 (Montrer SIRT2 Anticorps) maintains cellular iron levels by binding to and deacetylating nuclear factor erythroid-derived 2 (Montrer NFE2 Anticorps)-related factor 2 (NRF2 (Montrer GABPA Anticorps)) on lysines 506 and 508, leading to a reduction in total and nuclear NRF2 (Montrer GABPA Anticorps) levels.

  9. basal function of NRF2 (Montrer GABPA Anticorps) in colorectal cancer

  10. NRF2 (Montrer GABPA Anticorps) is regulated at protein level by proteasomal degradation via KEAP1 (Montrer KEAP1 Anticorps). Data suggest that antioxidant-induced up-regulation of NRF2 (Montrer GABPA Anticorps) expression (a) overcomes KEAP1 (Montrer KEAP1 Anticorps) regulation, (b) activates NRF2 (Montrer GABPA Anticorps) translocation to nucleus, and (c) activates antioxidant response element. (NRF2 (Montrer GABPA Anticorps) = nuclear factor [erythroid-derived 2]-like 2 protein; KEAP1 (Montrer KEAP1 Anticorps) = Kelch-like ECH-associated protein 1 (Montrer KEAP1 Anticorps))

Mouse (Murine) Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) interaction partners

  1. These results suggest that the Keap1 (Montrer KEAP1 Anticorps)/Nrf2 axis plays a critical role in NFATc1 (Montrer NFATC1 Anticorps) expression and osteoclastogenic progression.

  2. Low NRF2 expression is associated with progression of hepatic fibrosis.

  3. Findings show that NRF2 drives the cell cycle entry and differentiation of long-term hematopoietic stem cells at the expense of their quiescence and maintenance, an effect that appears to be beneficial for prompt recovery from blood loss. Study proposes that the appropriate control of NRF2 activity by KEAP1 (Montrer KEAP1 Anticorps) is essential for maintaining HSCs and guarantees their stress-induced regenerative response.

  4. The studies tested the role of Nrf2 during Streptococcus pneumoniae pneumonia and identified Nrf2-dependent genes and pathways in lung tissue and in recruited neutrophils.

  5. results provide mechanistic insight into Nrf2 action in the control of inflammation and cell proliferation through regulation of a proinflammatory cytokine with a key function in various inflammatory diseases

  6. Systemic NRF2 activation by Keap1 (Montrer KEAP1 Anticorps) knockdown alleviates multiple-organ inflammation and improves the survival rate of Sf mice.

  7. Hypoactivity of NRF2 in Krt16 (Montrer KRT16 Anticorps)-/- footpad skin correlated with decreased levels or activity of upstream NRF2 activators.

  8. Lack of Nrf2 enhances susceptibility to mycotoxin-induced kidney disease. Male mice were more sensitive than females.

  9. This study indicated that MAN can protect osteoblast against oxidative damage by modulation of ERK5 (Montrer MAPK7 Anticorps)/Nrf2 signaling, which can be new agent for osteoporosis.

  10. In conclusion, quercetin protected mice from d-galactose-induced cognitive functional impairment and neuronal cell apoptosis via activation of the Nrf2-ARE signaling pathway.

NRF2 (NFE2L2) profil antigène

Antigen Summary

This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters\; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with NRF2 (NFE2L2)

  • nuclear factor (erythroid-derived 2)-like 2a (nfe2l2a) anticorps
  • nuclear factor (erythroid-derived 2)-like 2 (nfe2l2) anticorps
  • nuclear factor (erythroid-derived 2)-like 2 (NFE2L2) anticorps
  • nuclear factor, erythroid 2-like 2 (NFE2L2) anticorps
  • nuclear factor, erythroid derived 2, like 2 (Nfe2l2) anticorps
  • AI194320 anticorps
  • NF-E2R2 anticorps
  • nfe2l2 anticorps
  • NRF2 anticorps
  • wu:fc15g09 anticorps
  • wu:fj67e03 anticorps

Protein level used designations for NFE2L2

Nrf2a , nuclear factor (erythroid-derived 2)-like 2 , nuclear factor erythroid 2-related factor 2 , ECH , NF-E2-related factor 2 , NFE2-related factor 2 , nuclear factor, erythroid derived 2, like 2 , HEBP1 , nuclear factor erythroid-derived 2-like 2 , nrf2 , nuclear factor erythroid 2-like 2

GENE ID SPECIES
360149 Danio rerio
444736 Xenopus laevis
396014 Gallus gallus
478813 Canis lupus familiaris
497024 Bos taurus
100516343 Sus scrofa
4780 Homo sapiens
18024 Mus musculus
83619 Rattus norvegicus
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