Aperçu des produits pour anti-RPS6KA1 (RPS6KA1) Anticorps

Full name:
anti-Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 Anticorps (RPS6KA1)
Chez www.anticorps-enligne.fr sont 394 Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) Anticorps de 28 de différents fournisseurs disponibles. De plus, nous expédions RPS6KA1 Protéines (12) et RPS6KA1 Kits (10) et beaucoup plus de produits pour cette protéine. Un total de 427 RPS6KA1 produits sont actuellement listés.
Synonymes:
CLS, hu-1, HU-3, ISPK-1, mapkapk1a, MAPKAPK1B, MRX19, p90-RSK2, p90rsk, pp90RSK2, RPS6KA, RSK, rsk1, RSK2, S6K-alpha3
afficher tous les anticorps Gène GeneID UniProt
RPS6KA1 20111  
RPS6KA1 81771 Q63531
RPS6KA1 6195 Q15418

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anti-RPS6KA1 Anticorps mieux référencés

  1. Chicken Monoclonal RPS6KA1 Primary Antibody pour IF, IP - ABIN967837 : Chung, Pelech, Blenis: Mitogen-activated Swiss mouse 3T3 RSK kinases I and II are related to pp44mpk from sea star oocytes and participate in the regulation of pp90rsk activity. dans Proceedings of the National Academy of Sciences of the United States of America 1991 (PubMed)
    Show all 5 references for 967837

  2. Human Polyclonal RPS6KA1 Primary Antibody pour EIA - ABIN358393 : Roux, Ballif, Anjum, Gygi, Blenis: Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase. dans Proceedings of the National Academy of Sciences of the United States of America 2004 (PubMed)
    Show all 5 references for 358393

  3. Human Polyclonal RPS6KA1 Primary Antibody pour DB, WB - ABIN1881765 : Bohuslav, Chen, Kwon, Mu, Greene: p53 induces NF-kappaB activation by an IkappaB kinase-independent mechanism involving phosphorylation of p65 by ribosomal S6 kinase 1. dans The Journal of biological chemistry 2004 (PubMed)
    Show all 5 references for 1881765

  4. Cow (Bovine) Polyclonal RPS6KA1 Primary Antibody pour ELISA, ICC - ABIN361702 : De Cesare, Jacquot, Hanauer, Sassone-Corsi: Rsk-2 activity is necessary for epidermal growth factor-induced phosphorylation of CREB protein and transcription of c-fos gene. dans Proceedings of the National Academy of Sciences of the United States of America 1998 (PubMed)
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  5. Human Polyclonal RPS6KA1 Primary Antibody pour WB - ABIN197330 : Silverman, Frödin, Gammeltoft, Maller: Activation of p90 Rsk1 is sufficient for differentiation of PC12 cells. dans Molecular and cellular biology 2004 (PubMed)
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  6. Human Polyclonal RPS6KA1 Primary Antibody pour IF, IHC (p) - ABIN196796 : Wingate, Campbell, Peggie, Arthur: Nur77 is phosphorylated in cells by RSK in response to mitogenic stimulation. dans The Biochemical journal 2006 (PubMed)
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  7. Human Polyclonal RPS6KA1 Primary Antibody pour IF, WB - ABIN197328 : Itoh, Ding, Bains, Wang, Takeishi, Jalili, King, Walsh, Yan, Abe: Role of p90 ribosomal S6 kinase (p90RSK) in reactive oxygen species and protein kinase C beta (PKC-beta)-mediated cardiac troponin I phosphorylation. dans The Journal of biological chemistry 2005 (PubMed)
    Show all 3 references for 197328

  8. Human Polyclonal RPS6KA1 Primary Antibody pour ELISA, WB - ABIN1043905 : Chaturvedi, Poppleton, Stringfield, Barbier, Patel: Subcellular localization and biological actions of activated RSK1 are determined by its interactions with subunits of cyclic AMP-dependent protein kinase. dans Molecular and cellular biology 2006 (PubMed)

  9. Human Polyclonal RPS6KA1 Primary Antibody pour EIA, IHC (p) - ABIN954622 : Gao, Chaturvedi, Patel: p90 ribosomal S6 kinase 1 (RSK1) and the catalytic subunit of protein kinase A (PKA) compete for binding the pseudosubstrate region of PKAR1alpha: role in the regulation of PKA and RSK1 activities. dans The Journal of biological chemistry 2010 (PubMed)

Plus d’anticorps contre RPS6KA1 partenaires d’interaction

Mouse (Murine) Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) interaction partners

  1. In hippocampal neurons of wild-type mice, pP90RSK translocates into the nucleus upon stimulation with forskolin (left), whereas in Period1-knockout (Per1 (Montrer PER1 Anticorps)(-/-) ) mice (right) the kinase is trapped at the nuclear periphery

  2. Data show that the phosphoinositide-dependent kinase 1 (PDK1 (Montrer PDPK1 Anticorps))-p90 (Montrer GPAM Anticorps) kDa ribosomal S6 kinases (Rsks) Rsk1/2 pathway is critical for establishment and maintenance of a normal Langerhans cells (LC) network.

  3. IL-6 (Montrer IL6 Anticorps) induces the activation of the Stat3 (Montrer STAT3 Anticorps) signaling and promotes the downmodulation of the p90RSK/eEF2 (Montrer EEF2 Anticorps) and mTOR (Montrer FRAP1 Anticorps)/p70S6K (Montrer RPS6KB1 Anticorps) axes, while it does not affect the activation of AKT (Montrer AKT1 Anticorps).

  4. analysis of p38 (Montrer CRK Anticorps)-MK2 (Montrer KCNA2 Anticorps)-activated Rsk signaling in toll (Montrer TLR4 Anticorps)-like receptor-stimulated dendritic cells

  5. These data indicate that aripiprazole and quetiapine signal to specific nuclear targets of ERK (Montrer EPHB2 Anticorps), which for quetiapine occurs via an EGFR (Montrer EGFR Anticorps)-linked mechanism, possibly indicating involvement of this system in its action.

  6. hypoxia/reoxygenation (H/R)-mediated decrease in PKARIalpha protein levels leads to activation of RSK1, which via phosphorylation of NHE1 (Montrer SLC9A1 Anticorps) induces cardiomyocyte apoptosis.

  7. RSK1 Cys223 glutathionylation may contribute to regulate the levels of nitric in the brain.

  8. Our study highlights the importance of the p90RSK/ERK5 (Montrer MAPK7 Anticorps) module as a critical mediator of endothelial dysfunction in diabetes mellitus and atherosclerosis formation.

  9. Results show increased protein levels of Rsk1 and Rsk2 (Montrer RPS6KA3 Anticorps) in the striatum of Huntington disease (Montrer HTT Anticorps) mice and and striatal cells transfected with full-length mutant Huntingtin (Montrer HTT Anticorps).

  10. Type I keratin (Montrer KRT12 Anticorps) 17 (Montrer KRT17 Anticorps) protein is phosphorylated on serine 44 by p90 (Montrer GPAM Anticorps) ribosomal protein S6 kinase 1 (RSK1) in a growth- and stress-dependent fashion

Human Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) interaction partners

  1. Inhibition of RSK2 (Montrer RPS6KA3 Anticorps) was used to investigate the function of RSK2 (Montrer RPS6KA3 Anticorps) on PDK1 (Montrer PDK1 Anticorps)-induced inflammation. The phosphorylation of RSK2 (Montrer RPS6KA3 Anticorps) was detected when PDK1 (Montrer PDK1 Anticorps) was inhibited. Inhibition of RSK2 (Montrer RPS6KA3 Anticorps) reduced the PDK1 (Montrer PDK1 Anticorps)-induced cell invasion and cytokines secretion in human rheumatoid arthritis synovial MH7A cells. In response to TNF-alpha (Montrer TNF Anticorps), PDK1 (Montrer PDK1 Anticorps) could phosphorylate RSK2 (Montrer RPS6KA3 Anticorps) and activated RSK2 (Montrer RPS6KA3 Anticorps), then promoting the activation of NF-kappaB (Montrer NFKB1 Anticorps).

  2. Our finding demonstrates that RSK2 (Montrer RPS6KA3 Anticorps) directly phosphorylates stathmin (Montrer STMN1 Anticorps) and regulates microtubule polymerization to provide a pro-invasive and pro-metastatic advantage to cancer cells. Therefore, the RSK2 (Montrer RPS6KA3 Anticorps)-stathmin (Montrer STMN1 Anticorps) pathway represents a promising therapeutic target and a prognostic marker for metastatic human cancers.

  3. Data suggest that UBR5 (Montrer UBR5 Anticorps) down-regulates levels of TRAF3 (Montrer TRAF3 Anticorps), a key component of Toll (Montrer TLR4 Anticorps)-like receptor signaling, via the miRNA pathway; p90RSK is an upstream regulator of UBR5 (Montrer UBR5 Anticorps); p90RSK phosphorylates UBR5 (Montrer UBR5 Anticorps) as required for translational repression of TRAF3 (Montrer TRAF3 Anticorps) mRNA. (UBR5 (Montrer UBR5 Anticorps) = ubiquitin protein ligase E3 component n-recognin 5 (Montrer UBR5 Anticorps) protein; TRAF3 (Montrer TRAF3 Anticorps) = TNF receptor-associated factor 3 (Montrer TRAF3 Anticorps); p90RSK = 90 kDa ribosomal protein S6 (Montrer RPS6 Anticorps) kinase (Montrer RPS6KB1 Anticorps))

  4. Data indicate that BTG2 (Montrer BTG2 Anticorps), MAP3K11 (Montrer MAP3K11 Anticorps), RPS6KA1 and PRDM1 (Montrer PRDM1 Anticorps) as putative targets of microRNA miR (Montrer MLXIP Anticorps)-125b.

  5. VEGF-A (Montrer VEGFA Anticorps) driven Mdm2 (Montrer MDM2 Anticorps) phosphorylation on Ser166 is dependent on the ERK1/2 (Montrer MAPK1/3 Anticorps)/p90RSK signaling pathway in primary human endothelial cells.

  6. we discuss the function of the RSK2 (Montrer RPS6KA3 Anticorps) signaling axis by interactions with binding partners in cancer development--{REVIEW}

  7. Results showed that RSK2 (Montrer RPS6KA3 Anticorps) gene was overexpressed in osteosarcoma patients cells and its knockdown increased cell apoptosis, enhanced cell chemosensitivity, inhibits proliferation and migration, and weakened tumor formation.

  8. Upregulated expression of RSK2 (Montrer RPS6KA3 Anticorps) is associated with breast cancer.

  9. The p90RSK has an essential role in promoting tumor growth and proliferation in non-small cell lung cancer (NSCLC). BID (Montrer BID Anticorps) may serve as an alternative cancer treatment in NSCLC.

  10. RSK1 binds to EBP50 (Montrer SLC9A3R1 Anticorps) at its first PDZ domain (Montrer INADL Anticorps), and mitogen activated RSK1 phosphorylates EBP50 (Montrer SLC9A3R1 Anticorps) at T156, an event that is crucial for its nuclear localization

RPS6KA1 profil antigène

Antigen Summary

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS).

Alternative names and synonyms associated with RPS6KA1

  • ribosomal protein S6 kinase polypeptide 1 (Rps6ka1) anticorps
  • ribosomal protein S6 kinase, 90kDa, polypeptide 1 (RPS6KA1) anticorps
  • ribosomal protein S6 kinase, 90kDa, polypeptide 1 (rps6ka1) anticorps
  • ribosomal protein S6 kinase, 90kDa, polypeptide 3 (RPS6KA3) anticorps
  • CLS anticorps
  • hu-1 anticorps
  • HU-3 anticorps
  • ISPK-1 anticorps
  • mapkapk1a anticorps
  • MAPKAPK1B anticorps
  • MRX19 anticorps
  • p90-RSK2 anticorps
  • p90rsk anticorps
  • pp90RSK2 anticorps
  • RPS6KA anticorps
  • RSK anticorps
  • rsk1 anticorps
  • RSK2 anticorps
  • S6K-alpha3 anticorps

Protein level used designations for RPS6KA1

90 kDa ribosomal protein S6 kinase 1 , MAP kinase-activated protein kinase 1a , MAPK-activated protein kinase 1a , MAPKAP kinase 1a , MAPKAPK-1a , RSK-1 , S6K-alpha-1 , p90-RSK 1 , p90RSK1 , p90S6K , ribosomal S6 kinase 1 , ribosomal protein S6 kinase alpha-1 , ribosomal protein S6 kinase, 90kD, polypeptide 1; Ribosomal protein S6 kinase, 90kD, 1 , MAPKAPK1A , S6 protein kinase (Rsk-1) , S6K-alpha 1 , pp90RSK1 , dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1) , ribosomal protein S6 kinase alpha 1 , MAP kinase-activated protein kinase 1 , MAPK-activated protein kinase 1 , MAPKAP kinase 1 , MAPKAPK-1 , S6KII-alpha , p90-RSK , ribosomal protein S6 kinase 2 alpha , ribosomal protein S6 kinase II alpha , P90-RSK , S6 kinase II beta , S6KII-beta , ribosomal protein S6 kinase 2 beta , ribosomal protein S6 kinase II beta , MAP kinase-activated protein kinase 1b , MAPK-activated protein kinase 1b , MAPKAP kinase 1b , MAPKAPK-1b , RSK-2 , S6K-alpha-3 , insulin-stimulated protein kinase 1 , p90-RSK 3 , ribosomal S6 kinase 2 , ribosomal protein S6 kinase alpha-3

GENE ID SPECIES
20111 Mus musculus
81771 Rattus norvegicus
533908 Bos taurus
6195 Homo sapiens
386579 Gallus gallus
487353 Canis lupus familiaris
100057166 Equus caballus
100523972 Sus scrofa
445821 Xenopus laevis
6197 Homo sapiens
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