Aperçu des produits pour anti-TERT (TERT) Anticorps

Full name:
anti-Telomerase Reverse Transcriptase Anticorps (TERT)
Chez www.anticorps-enligne.fr sont 261 Telomerase Reverse Transcriptase (TERT) Anticorps de 25 de différents fournisseurs disponibles. De plus, nous expédions TERT Kits (77) et TERT Protéines (12) et beaucoup plus de produits pour cette protéine. Un total de 367 TERT produits sont actuellement listés.
Synonymes:
ATTERT, chTERT, CMM9, DKCA2, DKCB4, EST2, F5E19.190, F5E19_190, hEST2, hTRT, PFBMFT1, TCS1, telomerase reverse transcriptase, tert, TP2, TR, TRT

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anti-TERT Anticorps mieux référencés

  1. Human Monoclonal TERT Primary Antibody pour FACS, ICC - ABIN151763 : Zhang, Eguchi, Kruse, Gomez, Fakhrai, Schroter, Ma, Hoa, Minev, Delgado, Wepsic, Okada, Jadus: Antigenic profiling of glioma cells to generate allogeneic vaccines or dendritic cell-based therapeutics. dans Clinical cancer research : an official journal of the American Association for Cancer Research 2007 (PubMed)
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  2. Human Polyclonal TERT Primary Antibody pour IF, ELISA - ABIN1532759 : Nakamura, Morin, Chapman, Weinrich, Andrews, Lingner, Harley, Cech: Telomerase catalytic subunit homologs from fission yeast and human. dans Science (New York, N.Y.) 1997 (PubMed)
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  3. Human Polyclonal TERT Primary Antibody pour FACS, IF - ABIN388165 : Sekaric, Cherry, Androphy: Binding of human papillomavirus type 16 E6 to E6AP is not required for activation of hTERT. dans Journal of virology 2007 (PubMed)
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  4. Human Polyclonal TERT Primary Antibody pour ELISA, WB - ABIN1531730 : Meyerson, Counter, Eaton, Ellisen, Steiner, Caddle, Ziaugra, Beijersbergen, Davidoff, Liu, Bacchetti, Haber, Weinberg: hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization. dans Cell 1997 (PubMed)
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  5. Human Polyclonal TERT Primary Antibody pour IF, ELISA - ABIN1531729 : Wick, Zubov, Hagen: Genomic organization and promoter characterization of the gene encoding the human telomerase reverse transcriptase (hTERT). dans Gene 1999 (PubMed)
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  6. Human Polyclonal TERT Primary Antibody pour ELISA, WB - ABIN1532760 : Hisatomi, Ohyashiki, Ohyashiki, Nagao, Kanamaru, Hirata, Hibi, Tsukada: Expression profile of a gamma-deletion variant of the human telomerase reverse transcriptase gene. dans Neoplasia (New York, N.Y.) 2003 (PubMed)
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  7. Human Polyclonal TERT Primary Antibody pour DB, IF - ABIN390002 : Radan, Hughes, Teichroeb, Vieira Zamora, Jewer, Postovit, Betts: Microenvironmental regulation of telomerase isoforms in human embryonic stem cells. dans Stem cells and development 2014 (PubMed)
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  8. Human Polyclonal TERT Primary Antibody pour EIA - ABIN358545 : Jakob, Schroeder, Lukosz, Büchner, Spyridopoulos, Altschmied, Haendeler: Nuclear protein tyrosine phosphatase Shp-2 is one important negative regulator of nuclear export of telomerase reverse transcriptase. dans The Journal of biological chemistry 2008 (PubMed)
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  9. Human Polyclonal TERT Primary Antibody pour EIA - ABIN358472 : Okawa, Michaylira, Kalabis, Stairs, Nakagawa, Andl, Johnstone, Klein-Szanto, El-Deiry, Cukierman, Herlyn, Rustgi et al.: The functional interplay between EGFR overexpression, hTERT activation, and p53 mutation in esophageal epithelial cells with activation of stromal fibroblasts induces tumor development, invasion, and ... dans Genes & development 2007 (PubMed)
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Plus d’anticorps contre TERT partenaires d’interaction

Caenorhabditis elegans (C. elegans) Telomerase Reverse Transcriptase (TERT) interaction partners

  1. trt-1 is the Caenorhabditis elegans catalytic subunit of telomerase

Zebrafish Telomerase Reverse Transcriptase (TERT) interaction partners

  1. The expression of telomerase activity and TERT in retina implies that telomerase has functions other than the elongation of telomere. These findings could provide new insights on telomerase function in the nervous system.

  2. methylation status of the genes of telomerase reverse transcriptase (tert) and telomerase RNA (terc) was determined in brain tissues; study found that, regardless of the age of fish, the regulatory region of the tert gene was completely methylated, whereas the coding region remained unmethylated

  3. Telomerase-deficient zebrafish show p53 (Montrer TP53 Anticorps)-dependent premature aging and reduced lifespan in the first generation.

  4. These results suggest that TERT non-canonically functions in hematopoietic cell differentiation and survival in vertebrates, independently of its role in telomere homeostasis.

Candida albicans Telomerase Reverse Transcriptase (TERT) interaction partners

  1. Telomerase regulatory subunit Est3 in Candida species physically interacts with the TEN domain of TERT and telomeric DNA

Medaka Telomerase Reverse Transcriptase (TERT) interaction partners

  1. Tert was cloned from testis. It is expresed in embryo and adult, mostly in gonad and brain. 2 splice variants and an antisense transcript were identified.

  2. The Japanese medaka is a new vertebrate model for studying tert biology.

Human Telomerase Reverse Transcriptase (TERT) interaction partners

  1. We found that G allele of rs2736100 and G allele of rs2853669 in TERT gene, interaction between rs2736100 and smoking, and haplotype containing the rs2736100- G and rs2736109- A alleles were all associated with increased gastric cancer risk.

  2. In promoting the self-renewal symmetric division of hTERT(high) prostate cancer cells, WNT3a (Montrer WNT3A Anticorps) dramatically decreased the ratio of hTERT(high) prostate cancer cells undergoing asymmetric division. Increased WNT (Montrer WNT2 Anticorps)/beta-catenin (Montrer CTNNB1 Anticorps) signal activation was also detected in hTERT(high) prostate cancer cells. hTERT-mediated CSC properties were at least partially dependent on beta-catenin (Montrer CTNNB1 Anticorps).

  3. Data show that long noncoding RNA BC032469 could directly bind to miR (Montrer MLXIP Anticorps)-1207-5p and modulate the derepression of hTERT.

  4. TERT promoter mutations were present in 12.9% of primary papillary thyroid carcinomas, 10.5% of lymph node metastasis, and 52.4% of distant metastasis.

  5. TERT enhances translation in cells to regulate cancer cell proliferation.

  6. Low TERT expression is associated with glioblastomas.

  7. TERT-mediated G-strand extension and Ctc1-Stn1-Ten1-mediated C-strand fill-in are equally important for telomere length maintenance.

  8. CXCR2 (Montrer CXCR2 Anticorps) preferentially supports the maintenance of human pluripotent stem cell characteristics as well as facilitates ectodermal differentiation after the commitment to differentiation, and the mechanism might be associated with mTOR (Montrer FRAP1 Anticorps), beta-catenin (Montrer CTNNB1 Anticorps), and hTERT activities.

  9. Results showed that TERT promoter mutational status combined with IDH-mutation allowed simple classification of grade II/III gliomas for stratifying patients and clarifying diagnostic accuracy by supplementing standard histopathological criteria.

  10. The conformations of the essential telomerase RNA core domain were mapped within the active TERT ribonucleoprotein.

Mouse (Murine) Telomerase Reverse Transcriptase (TERT) interaction partners

  1. TERT has a role in neointima formation through epigenetic regulation of proliferative E2F1 (Montrer E2F1 Anticorps) target gene expression in smooth muscle cells.

  2. these findings support a model in which gain of TERT function modulates mTORC1 activity and induces autophagy.

  3. Regarding extratelomeric activities, our results showed a decrease of 64, 38 and 25% in the transcription of c-Myc (Montrer MYC Anticorps), Cyc (Montrer CYCS Anticorps)-D1 and TERT, respectively (p<0.05) after AZT treatment. Furthermore, we found an effect on cell migration, reaching an inhibition of 48% (p<0.05) and a significant passage-dependent increase on cell doubling time during treatment

  4. Results suggest that in mature Purkinje neurons, TERT is present both in the nucleus and in mitochondria, where it may participate in adaptive responses of the neurons to excitotoxic and radiation stress

  5. Wnt10a (Montrer WNT10A Anticorps)/beta-catenin (Montrer CTNNB1 Anticorps) signaling pathway is able to exacerbate keloid cell proliferation and inhibit the apoptosis of keloid cells through its interaction with TERT.

  6. This study reports the characterisation of two novel mouse TERT splice variants, Ins (Montrer INS Anticorps)-i1[1-102] (Insi1 for short) and Del-e12 (Montrer ELSPBP1 Anticorps)[1-40] (Dele12 for short) that have not been previously described. Insi1 represents an in-frame insertion of nucleotides 1-102 from intron 1, encoding a 34 amino acid insertion at amino acid 73.

  7. TERT may promote gastric cancer metastasis through the TERT-miR (Montrer MLXIP Anticorps)-29a-ITGB1 (Montrer ITGB1 Anticorps) regulatory pathway.

  8. TERT switches macrophages towards M1 phenotype by regulating NF-kappaB (Montrer NFKB1 Anticorps) signaling, but has limited effect on M2 macrophages polarization in vitro.

  9. miR (Montrer MLXIP Anticorps)-195 overexpressed in old mesenchymal stem cells (OMSCs) induces stem cell senescence deteriorating their regenerative ability by directly deactivating telomerase reverse transcriptase (Tert), and abrogation of miR (Montrer MLXIP Anticorps)-195 can reverse stem cell aging.

  10. findings identified a key role for TERT in fibroblast proliferation and survival essential for pulmonary fibrosis

Cow (Bovine) Telomerase Reverse Transcriptase (TERT) interaction partners

Arabidopsis thaliana Telomerase Reverse Transcriptase (TERT) interaction partners

  1. Telomere shortening is more rapid in fas (Montrer FASN Anticorps) tert double mutants than in fas1 (Montrer FAS Anticorps), fas2 or tert single mutant plants.

  2. Silencing of the AtTERT gene is associated with increased H3K27me3 loading and maintenance of its euchromatic environment.

  3. study reports the physical interaction of an Arabidopsis POT1 (Montrer POT1 Anticorps) protein, POT1A (Montrer POT1 Anticorps) (At5g05210), with an N-terminal peptide of the catalytic subunit of the telomerase TERT encoded by a 5' mRNA splicing variant

  4. AtTERT, the telomerase catalytic subunit, accumulates in the plant nucleolus, and AtNAP57 (Montrer DKC1 Anticorps) associates with active telomerase RNP (Montrer RNPC3 Anticorps) particles in an RNA-dependent manner.

  5. Attert (-/-) mutant plants were propagated from seeds coming either from the lower-most or the upper-most siliques (L- and U-plants) and the length of their telomeres were followed over several generations.

TERT profil antigène

Antigen Summary

Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified\; the full-length sequence of some variants has not been determined. Alternative splicing at this locus is thought to be one mechanism of regulation of telomerase activity.

Alternative names and synonyms associated with TERT

  • Telomerase Reverse Transcriptase (trt-1) anticorps
  • telomerase reverse transcriptase (Tert) anticorps
  • telomerase reverse transcriptase (tert) anticorps
  • telomerase reverse transcriptase (TRT1) anticorps
  • telomerase reverse transcriptase (CMU_003490) anticorps
  • telomerase reverse transcriptase (VDBG_04487) anticorps
  • Telomerase catalytic subunit (GL50803_16225) anticorps
  • telomerase reverse transcriptase (TERT) anticorps
  • ATTERT anticorps
  • chTERT anticorps
  • CMM9 anticorps
  • DKCA2 anticorps
  • DKCB4 anticorps
  • EST2 anticorps
  • F5E19.190 anticorps
  • F5E19_190 anticorps
  • hEST2 anticorps
  • hTRT anticorps
  • PFBMFT1 anticorps
  • TCS1 anticorps
  • telomerase reverse transcriptase anticorps
  • tert anticorps
  • TP2 anticorps
  • TR anticorps
  • TRT anticorps

Protein level used designations for TERT

Telomerase Reverse Transcriptase family member (trt-1) , telomerase reverse transcriptase , hypothetical protein , Telomerase catalytic subunit , telomerase catalytic subunit , telomerase-associated protein 2 , telomerase reverse transcriptase beta

GENE ID SPECIES
172688 Caenorhabditis elegans
658162 Tribolium castaneum
796551 Danio rerio
3640729 Candida albicans SC5314
3640809 Candida albicans SC5314
6997965 Cryptosporidium muris RN66
9530095 Verticillium alfalfae VaMs.102
100049443 Oryzias latipes
5702495 Giardia lamblia ATCC 50803
7015 Homo sapiens
21752 Mus musculus
301965 Rattus norvegicus
518884 Bos taurus
403412 Canis lupus familiaris
492280 Sus scrofa
420972 Gallus gallus
100732437 Cavia porcellus
831548 Arabidopsis thaliana
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