anti-6-Pyruvoyltetrahydropterin Synthase (PTS) Anticorps

The enzyme encoded by PTS catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. De plus, nous expédions PTS Protéines (14) et PTS Kits (6) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
PTS 29498 P27213
PTS 19286 Q9R1Z7
PTS 5805 Q03393
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Top anti-PTS Anticorps sur anticorps-enligne.fr

Showing 10 out of 51 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Humain Lapin Inconjugué ICC, IF, IHC (p), WB WB Image Sample (50 ug of whole cell lysate) A: mouse stomach 15% SDS PAGE antibody diluted at 1:1000 WB Image Sample (30 ug of whole cell lysate) A: H1299 15% SDS PAGE antibody diluted at 1:1000 100 μL 3 to 4 Days
$466.18
Détails
Humain Lapin Inconjugué ELISA, WB Western blot analysis of PTS using HuvEc whole cell lysates 100 μL 11 to 12 Days
$390.77
Détails
Humain Lapin Inconjugué IHC (p), ELISA Human PTS Immunohistochemistry(IHC) 7815 100 μL 14 to 16 Days
$247.82
Détails
Humain Lapin Inconjugué IP, WB Immunoprecipitation of PTS transfected lysate using anti-PTS MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with PTS MaxPab rabbit polyclonal antibody (D01) . Western Blot analysis of PTS expression in transfected 293T cell line by PTS MaxPab polyclonal antibody.Lane 1: PTS transfected lysate(16.40 KDa).Lane 2: Non-transfected lysate. 100 μL 11 to 12 Days
$425.71
Détails
Boeuf (Vache) Lapin Inconjugué WB   100 μL 2 to 3 Days
$289.00
Détails
Humain Souris Inconjugué ELISA, WB Western blot analysis of mouse kidney lysates (Lane 1, 40 ug) and recombinant protein (Lane 2 is 1000 ng; Lane 3 is 500 ng) with PTS monoclonal antibody, clone AT2B2  at 1 : 500 dilution. Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. 100 μL 11 to 12 Days
$356.00
Détails
Humain Lapin Inconjugué IF/ICC, WB Western blot analysis of extracts of various cell lines, using PTS antibody (ABIN5973727) at 1/1000 dilution. Immunofluorescence analysis of MCF-7 cells using PTS antibody (ABIN5973727). Blue: DAPI for nuclear staining. 100 μL 11 to 16 Days
$426.40
Détails
Humain Lapin Inconjugué IF, WB Western blot analysis of extracts of various cell lines, using PTS antibody. Immunofluorescence analysis of MCF-7 cells using PTS antibody. 200 μL 12 to 14 Days
$438.90
Détails
Humain Lapin Inconjugué IHC, WB 100 μL 11 to 13 Days
$366.77
Détails
Humain Lapin Inconjugué ICC, IHC, IHC (p), WB   100 μL 11 to 14 Days
$537.17
Détails

Plus d’anticorps contre PTS partenaires d’interaction

Silk Worm 6-Pyruvoyltetrahydropterin Synthase (PTS) interaction partners

  1. Disruption of PTPS Gene Causing Pale Body Color and Lethal Phenotype in the Silkworm, Bombyx mori.

Mouse (Murine) 6-Pyruvoyltetrahydropterin Synthase (PTS) interaction partners

  1. biopterin contents in the brains of these knock-out mice were moderately decreased from postnatal day 0 (P0) and remained constant up to P21

  2. ptps has a role in 6-pyruvoyltetrahydropterin synthase- or BH4-biosynthetic activity with IGF-1

Human 6-Pyruvoyltetrahydropterin Synthase (PTS) interaction partners

  1. Severe neurological impairment from BH4 deficiency could be prevented by newborn screening for hyperphenylalaninemia (HPA) and proper metabolic management.

  2. A total of 43 mutations were identified in the PTS gene in a screen of East Asian populations, comprising 22 previously reported mutations and 21 new discovered mutations.

  3. The mutant characterization of PTPS gene was coincident with other early studies in Chinese. The novel mutation L127F was considered as a pathogenetic mutation and associated with severe clinical phenotype.

  4. Our data show that PTPS induction is necessary for optimized BH4 synthesis in cytokine-stimulated human coronary artery endothelial cells and point to IL-1beta as a leading cytokine in this process.

  5. Hyperphenylalaninemia may be caused by deficiency of Phe hydroxylase or by deficiency of co-factor BH(4).

  6. Human PTS was efficiently expressed in noradrenergic regions but only in a small number of dopaminergic neurons.

  7. Expression of PTS was significantly decreased in PD cases.

  8. We suggest that the serum prolactin level may be a more sensitive marker than the CSF HVA level to guide the dose adjustment of L-Dopa/carbidopa in the management of patients with PTPS deficiency.

  9. mutational analysis in Chinese hyperphenylalaninemia caused by tetrahydrobiopterin synthesis deficiency

PTS profil antigène

Profil protéine

The enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia.

Gene names and symbols associated with PTS

  • 6-pyruvoyltetrahydropterin synthase (PTS) anticorps
  • 6-pyruvoyltetrahydropterin synthase L homeolog (pts.L) anticorps
  • 6-pyruvoyltetrahydropterin synthase (Pts) anticorps
  • 6-pyruvoyltetrahydropterin synthase (azo3118) anticorps
  • 6-pyruvoyltetrahydropterin synthase (Xfasm12_0164) anticorps
  • 6-pyruvoyltetrahydropterin synthase (HUTA_RS09790) anticorps
  • 6-pyruvoyltetrahydropterin synthase (Cyan8802_3683) anticorps
  • 6-pyruvoyltetrahydropterin synthase (ptsA) anticorps
  • 6-pyruvoyltetrahydropterin synthase (NMAG_RS16995) anticorps
  • 6-pyruvoyltetrahydropterin synthase (pts) anticorps
  • 6-pyruvoyltetrahydropterin synthase (DICPUDRAFT_151723) anticorps
  • 6-pyruvoyl-tetrahydropterin synthase (Pts) anticorps
  • DDBDRAFT_0232952 anticorps
  • DDB_0232952 anticorps
  • PTPS anticorps
  • Pts anticorps
  • zgc:162276 anticorps

Protein level used designations for PTS

6-pyruvoyltetrahydropterin synthase , 6-pyruvoyl tetrahydrobiopterin synthase , putative 6-pyruvoyltetrahydropterin synthase , PTP synthase , PTPS

GENE ID SPECIES
374144 Gallus gallus
495178 Xenopus laevis
506860 Bos taurus
611326 Canis lupus familiaris
692791 Bombyx mori
711642 Macaca mulatta
739126 Pan troglodytes
2734138 Bdellovibrio bacteriovorus HD100
4607798 Azoarcus sp. BH72
6121154 Xylella fastidiosa M12
8384294 Halorhabdus utahensis DSM 12940
8393025 Cyanothece sp. PCC 8802
8621869 Dictyostelium discoideum AX4
8826381 Natrialba magadii ATCC 43099
100073330 Danio rerio
100190535 Taeniopygia guttata
10500652 Dictyostelium purpureum
29498 Rattus norvegicus
19286 Mus musculus
5805 Homo sapiens
100171600 Pongo abelii
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