anti-Cytochrome B5 Reductase 3 (CYB5R3) Anticorps

CYB5R3 encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. De plus, nous expédions Cytochrome B5 Reductase 3 Kits (17) et Cytochrome B5 Reductase 3 Protéines (16) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
CYB5R3 1727 P00387
CYB5R3 25035 P20070
CYB5R3 109754 Q9DCN2
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Top anti-Cytochrome B5 Reductase 3 Anticorps sur anticorps-enligne.fr

Showing 10 out of 160 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB 100 μL 2 to 3 Days
$289.00
Détails
Chien Lapin Inconjugué IP, IHC, WB Immunohistochemical analysis of CYB5R3 staining in human liver cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of CYB5R3 expression in HeLa (A) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Détails
Humain Lapin Inconjugué IHC, ELISA, WB Western blot analysis of extracts from HepG2/COLO/HuvEc/HT-29/K562 cells, using CYB5R3 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human placenta tissue, using CYB5R3 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg 2 to 3 Days
$302.50
Détails
Humain Chèvre Inconjugué ELISA, IHC, WB   100 μg 6 to 7 Days
$429.84
Détails
Humain Chèvre Inconjugué ELISA, WB 0.1 mg 2 to 3 Days
$515.63
Détails
Souris Chèvre Inconjugué ELISA, WB   100 μg 6 to 7 Days
$429.84
Détails
Boeuf (Vache) Chèvre Inconjugué EIA, WB AP23661PU-N Cyb5r3 antibody staining of Mouse Lung lysate at 0.1 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg 6 to 8 Days
$445.50
Détails
Souris Chèvre Inconjugué ELISA, WB 0.1 mg 2 to 3 Days
$515.63
Détails
Humain Lapin Inconjugué ELISA, IHC, WB 100 μL Disponible
$363.46
Détails
Humain Chèvre Inconjugué ELISA, IHC, IHC (p), WB Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg 11 to 14 Days
$484.00
Détails

anti-Cytochrome B5 Reductase 3 Anticorps mieux référencés

  1. Mouse (Murine) Polyclonal CYB5R3 Primary Antibody pour ELISA, WB - ABIN4301428 : Fernandez-Borja, Janssen, Verwoerd, Hordijk, Neefjes: RhoB regulates endosome transport by promoting actin assembly on endosomal membranes through Dia1. dans Journal of cell science 2005 (PubMed)

  2. Human Polyclonal CYB5R3 Primary Antibody pour ICC, IF - ABIN4301429 : Jakobs, Mikula, Havemeyer, Strzalkowska, Borowa-Chmielak, Dzwonek, Gajewska, Hennig, Ostrowski, Clement: The N-reductive system composed of mitochondrial amidoxime reducing component (mARC), cytochrome b5 (CYB5B) and cytochrome b5 reductase (CYB5R) is regulated by fasting and high fat diet in mice. dans PLoS ONE 2014 (PubMed)

Plus d’anticorps contre Cytochrome B5 Reductase 3 partenaires d’interaction

Human Cytochrome B5 Reductase 3 (CYB5R3) interaction partners

  1. study indicated that novel homozygous mutation p.Arg192Cys in CYB5R3 gene present in eight cases and the possibility of high prevalence of heterozygous in Indian population causing Type I recessive congenital methemoglobinemia.

  2. Data suggest that cytochrome b5 (CYB5) and cytochrome b5 reductase 3 (CYB5R3) can reduce human cytoglobin (CYGB) and zebrafish cytoglobins at rates up to 250-fold higher than those reported for the known physiological substrates, hemoglobin and myoglobin; the three proteins (CYB5+CYB5R3+CYGB) appear to constitute a metabolon involved in generation of nitric oxide.

  3. CYB5R3 promotes colonization and metastasis formation and is a prognostic marker of disease-free and overall survival in estrogen receptor-negative breast cancer.

  4. Variants in CYB5A and CYB5R3 should be considered in the evaluation of breast cancer risk in African American women.

  5. Genetic variation in CYB5R3 is associated with methemoglobin levels in preterm infants receiving nitric oxide therapy.

  6. The results unveil a potential mechanism of action by which CYB5R3 deficiency contributes to the pathophysiological underpinnings of neurological disorders in RHM patients.

  7. NADH-CYB5R deficiency causes two forms of recessive congenital methemoglobinemia with cyanosis.

  8. Dapsone-associated methemoglobinemia in a patient with slow NAT2*5B haplotype and impaired cytochrome b5 reductase activity

  9. A comprehensive overview of the study of structure and function of human cytochrome b5 reductase.

  10. Data indicate that mitochondrial amidoxime reducing components 1 and 2 together with the electron transport proteins NADH-cytochrome b5 reductase (CYB5R) and cytochrome b5 (CYB5) catalyze the reduction of N-hydroxylated compounds such as amidoximes.

  11. Population frequency and age of c.806C > T mutation in CYB5R3 gene as cause of recessive congenital methemoglobinemia in Yakutia.

  12. Novel large deletion c.22-1320_633+1224del in the CYB5R3 gene from patients with hereditary methemoglobinemia

  13. CYB5R3 gene of three probands with type I methemoglobinemia and their relatives were sequenced revealing several putative causative mutations; in one subject multiple mutations were present

  14. We conclude that Cytochrome b(5)and cytochrome b(5) reductase catalyze the reduction of arylhydroxylamines in breast tissue.

  15. novel allelic mutation identified at codon 235 is in helix 5; first report of mental retardation because of the novel mutation, along with a second mutation in the NADH-b5R gene in an Indian family with recessive congenital methemoglobinemia Type II

  16. Dia1 is localized to the perinuclear endoplasmic reticulum in an RNA-zipcode-independent manner in fibroblasts.

  17. novel cSNPs associated with significantly altered protein expression and/or hydroxylamine reduction activities, but only minimally impact overall observed phenotypic variability

  18. It was shown that Yakut patients have none of three missence mutations, Arg57Gln, Leu72Pro, and Val105Met, described in case of this disease in the neighboring populations, Chinese and Japanese, inhabiting the territories south of Yakutia

  19. A decrease of the activity of membrane-bound NADH-methemoglobin reductase and a change of physical state of the lipid bilayer of membranes under oxidative stress were found in erythrocytes in vivo and in vitro.

  20. Amino acid substitution results in congsenital methemoglobinemia.

Mouse (Murine) Cytochrome B5 Reductase 3 (CYB5R3) interaction partners

  1. Amino and carboxy terminal fragments of mDia1 form a tetrameric complex composed of two interlocking N+C dimers.

  2. Nucleation is achieved by a mechanism involving APC-B dimerization and recruitment of multiple actin monomers. Further, APC-B nucleation activity is synergistic with its in vivo binding partner, the formin mDia1

  3. an N-terminal domain spanning residues 129-369(DID) is sufficient for auto-inhibition, but alone is not sufficient for RhoA relief of auto-inhibition, suggesting that sequences N-terminal to DID are important to RhoA binding.

  4. Dia1 is required for the formation of the actin coat around endosomes downstream of RhoB, connecting membrane trafficking with the regulation of actin dynamics.

  5. Dia1 and IQGAP1 interact in cell migration and phagocytic cup formation.

Cytochrome B5 Reductase 3 (CYB5R3) profil antigène

Profil protéine

This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias.

Gene names and symbols associated with CYB5R3

  • cytochrome b5 reductase 3 (CYB5R3) anticorps
  • cytochrome b5 reductase 3 (Cyb5r3) anticorps
  • cytochrome b5 reductase 3 (cyb5r3) anticorps
  • cytochrome b5 reductase 3 L homeolog (cyb5r3.L) anticorps
  • NADH-cytochrome b5 reductase (CNM00240) anticorps
  • NADH-cytochrome b5 reductase (Tb11.47.0018) anticorps
  • NADH-cytochrome b5 reductase (cyb5r1) anticorps
  • 0610016L08Rik anticorps
  • 2500002N19Rik anticorps
  • B5R anticorps
  • C85115 anticorps
  • CB5R anticorps
  • DDBDRAFT_0218707 anticorps
  • DDBDRAFT_0266821 anticorps
  • DDB_0218707 anticorps
  • DDB_0266821 anticorps
  • Dia-1 anticorps
  • dia1 anticorps
  • fc32h03 anticorps
  • Nadhcb5 anticorps
  • RNNADHCB5 anticorps
  • WU:AL591952.1-001 anticorps
  • WU:AL591952.1-002 anticorps
  • WU:AL591952.1-003 anticorps
  • WU:Cyb5r3 anticorps
  • wu:fc32h03 anticorps
  • zgc:77071 anticorps

Protein level used designations for CYB5R3

NADH-cytochrome b5 reductase 3 , NADH-cytochrome b5 reductase 3 membrane-bound form , NADH-cytochrome b5 reductase 3 soluble form , diaphorase-1 , B5R , Diaphorase (NADH) (cytochrome b-5 reductase) , diaphorase 1 , diaphorase 1 (NADH) , NADH-cytochrome b5 reductase , cytochrome b5 reductase 3

GENE ID SPECIES
1727 Homo sapiens
418220 Gallus gallus
25035 Rattus norvegicus
109754 Mus musculus
324560 Danio rerio
380169 Xenopus laevis
458883 Pan troglodytes
474479 Canis lupus familiaris
515773 Bos taurus
3255044 Cryptococcus neoformans var. neoformans JEC21
3664333 Trypanosoma brucei brucei strain 927/4 GUTat10.1
8625067 Dictyostelium discoideum AX4
100170571 Xenopus (Silurana) tropicalis
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