Desmin (DES) Kits ELISA

DES encodes a muscle-specific class III intermediate filament. De plus, nous expédions Desmin Anticorps (378) et Desmin Protéines (30) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
DES 1674 P17661
DES 64362 P48675
DES 13346 P31001
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Top Desmin Kits ELISA sur anticorps-enligne.fr

Showing 10 out of 73 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Fournisseur Livraison Prix Détails
Humain 0.114 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests Connectez-vous pour afficher 13 to 16 Days
$663.16
Détails
Rat 1.56 ng/mL 6.25-400 ng/mL Typical standard curve 96 Tests Connectez-vous pour afficher 13 to 16 Days
$1,107.33
Détails
Souris 0.047 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Connectez-vous pour afficher 13 to 16 Days
$682.11
Détails
Lapin 0.1 ng/mL 0.5-10 ng/mL   96 Tests Connectez-vous pour afficher 15 to 18 Days
$707.14
Détails
Cobaye 0.1 ng/mL 0.5-10 ng/mL   96 Tests Connectez-vous pour afficher 15 to 18 Days
$707.14
Détails
Poulet 1.875 ng/mL 3.125-200 ng/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$715.00
Détails
Porc 0.094 ng/mL 0.156-10 ng/mL   96 Tests Connectez-vous pour afficher 12 to 14 Days
$715.00
Détails
Singe 0.1 ng/mL 0.5-10 ng/mL   96 Tests Connectez-vous pour afficher 15 to 18 Days
$707.14
Détails
Chien 0.1 ng/mL 0.5-10 ng/mL   96 Tests Connectez-vous pour afficher 15 to 18 Days
$707.14
Détails
Boeuf (Vache) 0.1 ng/mL 0.5-10 ng/mL   96 Tests Connectez-vous pour afficher 15 to 18 Days
$707.14
Détails

Desmin Kits ELISA mieux référencés

  1. Human Desmin Kit ELISA pour Sandwich ELISA - ABIN417384 : Kobayashi, Olson, Sly, Swanson, Chung, Naryshkin, Narasimhan, Bhattacharyya, Mullenix, Chen: Utility of survival motor neuron ELISA for spinal muscular atrophy clinical and preclinical analyses. dans PLoS ONE 2011 (PubMed)
    Show all 3 Pubmed References

  2. Human Desmin Kit ELISA pour Sandwich ELISA - ABIN1379903 : Tidball: Desmin at myotendinous junctions. dans Experimental cell research 1992 (PubMed)

Plus Kits ELISA pour Desmin partenaires d'interaction

Zebrafish Desmin (DES) interaction partners

  1. Desmin intermediate filaments are required for normal active force generation.

  2. Desmin distribution during muscle maturation changes from dispersed aggregates to a perinuclear concentration to striated afterwards.

Human Desmin (DES) interaction partners

  1. The DES-p.Glu401Asp mutation causes predominant inherited left ventricular arrhythmogenic cardiomyopathy/dysplasia with a high incidence of adverse clinical events in the absence of skeletal myopathy or conduction system disorders.

  2. There was no association of any of the rs1058261 genotypes with hypertension at the age of 50. At age of 60, after adjustment for gender and body mass index, subjects with the genotype CC had higher incidence of cerebrovascular events compared with the T allele (1.6%) (p = 0.046). In addition, those with CC genotype had a higher incidence of all combined cardiovascular events compared with subjects with the T allele.

  3. A novel mutation (c.679 C>T /p.R227C) in exon 3 of DES was identified and cosegregated with the affected members of a Chinese family with isolated Dilated cardiomyopathy (DCM) phenotypes (left ventricle and left atrial diameters).

  4. Desmin, Glial Fibrillary Acidic Protein, Vimentin, and Peripherin are type III intermediate filaments that have roles in health and disease [review]

  5. Phenotypic expression of a novel desmin gene mutation: hypertrophic cardiomyopathy followed by systemic myopathy.

  6. Using a combination of co-sedimentation centrifugation, viscometric assays and electron microscopy of negatively stained filaments to analyse the in vitro assembly of desmin filaments, this study shows that the binding of CRYAB to desmin is subject to its assembly status, to the subunit organization within filaments formed and to the integrity of the C-terminal tail domain of desmin.

  7. Targeted sequencing revealed trigenic mutations: c.700G>A/p.E234K in DES, c.2966G>A/p.R989H in MYPN, and c.5918G>C/p.R1973P in CACNA1C in a family of hypertrophic cardiomyopathy with early repolarization and short QT syndrome.

  8. demonstrate that the expression of mutant desmin causes disruption of the extrasarcomeric desmin cytoskeleton and extensive mitochondrial abnormalities regarding subcellular distribution, number and shape

  9. Mutation in the Core Structure of Desmin Intermediate Filaments Affects Myoblast Elasticity

  10. Data show that the filament elongation of both desmin and keratin K8/K18 proceeds very similar to that of vimentin.

  11. Cdk1-induced desmin phosphorylation is required for efficient separation of desmin-IFs and generally detected in muscular mitotic cells in vivo.

  12. Desmin, Lamin A/C, MMP9, and histone H4 were upregulated in the placental villi of women experiencing early pregnancy loss.

  13. Ile367Phe, Pro419Ser, and Arg415Glu mutations were associated with desminopathy causing cardiomyopathy in 4 families studied.

  14. Increasing desmin abnormalities were correlated with diastolic dysfunction progression.

  15. expression level of mutant versus wild-type desmin in mouse model as well as in skeletal muscle specimens derived from human R350P desminopathies; findings demonstrate missense-mutant desmin inflicts changes of the subcellular localization and turnover of desmin itself and of direct desmin-binding partners

  16. Results propose that the mutations affect desmin structure and cause its aberrant folding and subsequent aggregation, triggering disruption of myofibrils organization.

  17. identified disruption of the desmin system in gastrocnemius myofibers as an index of the myopathy and limitation of muscle function in patients with peripheral artery disease.

  18. The desmin intermediate filament network plays a major role in striated muscle development and maintenance by integrating and coordinating most cellular components necessary for proper mechanochemical signaling, organelle cross-talk, energy production and trafficking processes required for proper tissue homeostasis. [Review]

  19. Data suggest that loss of the desmin-p. A120D filament localization at the intercalated disk indicates its clinical arrhythmogenic potential.

  20. we describe a new mutation located in the coiled 1B domain of desmin and associated with a predominant cardiac involvement and a high degree of cardiac sudden death in a large Indian pedigree with 12 affected members

Mouse (Murine) Desmin (DES) interaction partners

  1. Data suggest that mutated desmin markedly impedes myocyte structure and function at pre-symptomatic stages of myofibrillar myopathies.

  2. Moderate MnSOD and/or catalase overexpression in desmin-null hearts leads to a marked decrease in intracellular reactive oxygen species, ameliorates mitochondrial and other ultrastructural defects, minimizes myocardial degeneration and leads to a significant improvement of cardiac function.

  3. R349P mutant desmin-related remodeling of the 3D myofibrillar architecture during aging, which provides a structural basis for the progressive muscle weakness.

  4. demonstrate that the expression of mutant desmin causes disruption of the extrasarcomeric desmin cytoskeleton and extensive mitochondrial abnormalities regarding subcellular distribution, number and shape

  5. The disease-mutant desmin variants E245D and T453I exhibited increased binding affinity for nebulette, delayed filament assembly kinetics, and caused significant weakening of networks.

  6. desmin and alphaBeta-crystallin are localized at sarcoplasmic reticulum (SR)-mitochondria-associated membranes (MAMs), where they interact with VDAC, Mic60 - the core component of mitochondrial contact site and cristae organizing system (MICOS) complex - and ATP synthase, suggesting that these associations could be crucial in mitoprotection at different levels.

  7. Complete lack or markedly decreased expression of mutant R349P desmin impairs the structural and functional integrity of neuromuscular endplates.

  8. Cdk1-induced desmin phosphorylation is required for efficient separation of desmin-IFs and generally detected in muscular mitotic cells in vivo.

  9. the coordinated up-regulations of desmin and alpha- actinin specifically in the early stage of diastolic heart failure mouse models indicate a novel myocardial response.

  10. E413K mutation induces desmin network disorganization, desmin aggregate formation and alters the traction forces generation of single myoblasts.

  11. This study identifies desmin as a new Asb2b target for proteasomal degradation in cardiomyocytes and suggests that accumulation of desmin could contribute to UPS impairment in Hypertrophic cardiomyopathy mice and patients

  12. found that inhibition of the Rac1 pathway (a G protein signaling pathway involved in diverse cellular processes), antioxidant treatment, and stimulation of macroautophagy reduced desmin aggregation by up to 75% in this model

  13. This demonstration of biomechanical integration by the desmin intermediate filament system suggests that it plays an active biological role in muscle in addition to its accepted structural role

  14. expression level of mutant versus wild-type desmin in mouse model as well as in skeletal muscle specimens derived from human R350P desminopathies; findings demonstrate missense-mutant desmin inflicts changes of the subcellular localization and turnover of desmin itself and of direct desmin-binding partners

  15. Disruption of both nesprin 1 and desmin results in decreased lifespan, body weight and muscle strength.

  16. The desmin intermediate filament network plays a major role in striated muscle development and maintenance by integrating and coordinating most cellular components necessary for proper mechanochemical signaling, organelle cross-talk, energy production and trafficking processes required for proper tissue homeostasis. [Review]

  17. Desmin content and transversal stiffness of the left ventricle mouse cardiomyocytes and skeletal muscle fibers after a 30-day space flight on board "BION-M1" biosatellite

  18. the observed decline in [Ca(2+)]mit was due to desmin aggregate accumulation resulting in the loss of desmin mitochondria interactions

  19. expression detected specifically in the mylohyoid, strong expression evident after embryonic day 13, increased with age

  20. During fasting, desmin phosphorylation increases and enhances Trim32-mediated degradation of the desmin cytoskeleton, which appears to facilitate the breakdown of Z-bands and thin filaments.

Cow (Bovine) Desmin (DES) interaction partners

  1. Results show that expression of desmin increased during the late fattening stage of of hanwoo steers and it contributes to the muscle contractile apparatus.

Desmin (DES) profil antigène

Antigen Summary

This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.

Gene names and symbols associated with Desmin (DES) Kits ELISA

  • desmin (DES) anticorps
  • desmin, gene 1 L homeolog (des.1.L) anticorps
  • desmin, gene 1 (des.1) anticorps
  • desmin (des) anticorps
  • desmin a (desma) anticorps
  • desmin (Des) anticorps
  • desmin b (desmb) anticorps
  • desmin, gene 1 S homeolog (des.1.S) anticorps
  • desmin, gene 2 S homeolog (des.2.S) anticorps
  • cb290 anticorps
  • cmd1i anticorps
  • CSM1 anticorps
  • CSM2 anticorps
  • des anticorps
  • des-a anticorps
  • des-b anticorps
  • desm anticorps
  • desmin anticorps
  • fb59a12 anticorps
  • LGMD2R anticorps
  • LOC100220724 anticorps
  • MGC52614 anticorps
  • MGC75911 anticorps
  • MGC80853 anticorps
  • wu:fb59a12 anticorps
  • wu:fc11d08 anticorps
  • zgc:109859 anticorps
  • zgc:154009 anticorps

Protein level used designations for Desmin (DES) Kits ELISA

desmin , desmin, gene 1 , desmin-like , intermediate filament protein , muscle-specific intermediate filament desmin , fc11d08

GENE ID SPECIES
100059397 Equus caballus
100137488 Papio anubis
446868 Xenopus laevis
394739 Xenopus (Silurana) tropicalis
470657 Pan troglodytes
100136041 Oncorhynchus mykiss
100220724 Taeniopygia guttata
100402007 Callithrix jacchus
30148 Danio rerio
100586972 Nomascus leucogenys
395906 Gallus gallus
1674 Homo sapiens
64362 Rattus norvegicus
497091 Canis lupus familiaris
13346 Mus musculus
101097010 Felis catus
280765 Bos taurus
101117308 Ovis aries
100328890 Oryctolagus cuniculus
396725 Sus scrofa
100733478 Cavia porcellus
101837949 Mesocricetus auratus
768287 Danio rerio
379869 Xenopus laevis
733312 Xenopus laevis
Fournisseurs de qualité sélectionnés pour Desmin (DES) Kits ELISA
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