anti-Developmental Pluripotency Associated 3 (DPPA3) Anticorps

DPPA3 encodes a protein that in mice may function as a maternal factor during the preimplantation stage of development. De plus, nous expédions DPPA3 Protéines (7) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
DPPA3 359787 Q6W0C5
DPPA3 73708 Q8QZY3
DPPA3 297576 Q6IMK0
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Top anti-DPPA3 Anticorps sur

Showing 10 out of 28 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Livraison Prix Détails
Humain Lapin Inconjugué IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse embryo labeled with Anti-Stella/DPPA3 Polyclonal Antibody, Unconjugated (ABIN1713577) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL 14 to 21 Days
Humain Lapin Inconjugué IHC, IHC (p) 100 μg 11 to 14 Days
Humain Lapin Inconjugué WB 0.1 mg 11 to 14 Days
Humain Chèvre Inconjugué ELISA   100 μg 11 to 14 Days
Humain Lapin Inconjugué ELISA, WB 0.1 mg 2 to 3 Days
Humain Lapin Inconjugué ELISA, WB Western Blot of Stella Antibody Western Blot of Stella antibody.   Lane A:  293 cell lysate at 1 µg/mL.   Lane B:  293 cell lysate at 2 µg/mL.   Load:  35 µg per lane. Secondary antibody:   Peroxidase rabbit secondary antibody at 1:10,000 for 45 min at RT. Block:  5% BLOTTO overnight at 4°C. Predicted/Observed size:  56.0 kDa, ~18 kDa for Stella. 100 μg 1 to 2 Days
Humain Lapin Inconjugué ICC, IHC, WB Figure. Western Blot; Sample: Recombinant protein. DAB staining on IHC-P; Samples: Human Kidney Tissue 100 μg 15 to 18 Days
Humain Lapin Inconjugué WB   100 μL 11 to 14 Days
Humain Souris Inconjugué WB Western Blot analysis of DPPA3 expression in transfected 293T cell line by DPPA3 MaxPab polyclonal antibody.Lane 1: DPPA3 transfected lysate(17.49 KDa).Lane 2: Non-transfected lysate. 50 μg 11 to 12 Days
Humain Lapin Inconjugué WB   100 μg 11 to 16 Days

anti-DPPA3 Anticorps mieux référencés

  1. Human Polyclonal DPPA3 Primary Antibody pour IF (p), IHC (p) - ABIN1713577 : Wasielak, Więsak, Bogacka, Jalali, Bogacki: Zygote arrest 1, nucleoplasmin 2, and developmentally associated protein 3 mRNA profiles throughout porcine embryo development in vitro. dans Theriogenology 2016 (PubMed)

Plus d’anticorps contre DPPA3 partenaires d’interaction

Cow (Bovine) Developmental Pluripotency Associated 3 (DPPA3) interaction partners

  1. DPPA3 is a maternal factor important for correct epigenetic remodeling and normal embryonic development in cattle, indicating that the role of DPPA3 during early development is conserved between species.

Human Developmental Pluripotency Associated 3 (DPPA3) interaction partners

  1. Super-enhancers at the Nanog locus differentially regulate neighboring pluripotency-associated genes, in particular, DPPA3.

  2. We conclude that heterogeneous population of the HEK293T cells might be easily shifted towards expression of the pluripotency markers by ectopic expression of the SON factors or by growth in serum depleted media.

  3. Data suggest enforced expression of Stella into normal cells induces not only global DNA demethylation but also neoplastic transformation and increases metastatic ability; these changes involve altered regulation of neoplastic gene expression.

  4. Considering that impaired DNA methylation profiles are associated with various developmental or disease phenomena, Stella may be a powerful tool with which to study the biological effects of global DNA hypomethylation

  5. a role for STELLA in facilitating germline and endodermal differentiation of human ES cells

  6. human adult tissue-specific transcripts originate via retrotransposition of the pluripotent cell-specific gene, Dppa3

  7. These results demonstrate that PGC7/Stella is indispensable for the maintenance of methylation involved in epigenetic reprogramming after fertilization.

  8. In mice, this gene may play a role in oogenesis and primordial germ cell development.

  9. In mice, a targeted mutation results in reduced female fertility and may function as a mammalian maternal effect gene.

  10. In mice, knockout experiments show this gene may be a maternal factor in cleavage stage embryogenesis.

Mouse (Murine) Developmental Pluripotency Associated 3 (DPPA3) interaction partners

  1. Stella safeguards the unique oocyte epigenome by preventing aberrant de novo DNA methylation mediated by DNMT1 and UHRF1

  2. Stella insufficiency in oocytes may represent a critical mechanism that mediates the phenotypic effects of maternal obesity in embryos and offspring.

  3. To determine the reprogramming potential of germ cell- specific genes, a polycistronic gene cassette expressing Stella, Oct4 and Nanos2 in a lentiviral-based vector, was designed.

  4. Overexpression of Stella improves the efficiency of nuclear transfer reprogramming

  5. The absence of the DPPA3 cleavage products adversely affects pre-implantation development and female fertility.

  6. Through an in-depth bioinformatic analysis of potential interactors, PGC7 was linked to critical cellular processes including translation, RNA processing, cell cycle, and regulation of heterochromatin structure.

  7. PRDM1 and STELLA, while overlapping in putative primordial germ cells, also co-localize in several other tissues

  8. The authors show that loss of maternal Stella results in widespread transcriptional mis-regulation and a partial failure of maternal-to-zygotic transition.

  9. Data indicate STELLA's potential roles in building the fetal-placental connection.

  10. This study shows repression of the Dppa3 Locus in the absence of MAD2L2 embryonic stem cells.

  11. In-depth transcriptome analysis of this mESC state reveals Dppa3 as a direct downstream target of Tbx3.We show that Tbx3, a downstream target of Wnt signaling, fine tunes these divergent roles of Wnt signaling in mESCs

  12. Dppa3 has a critical role in generation of fully reprogrammed iPS cells and maintenance of Dlk1-Dio3 imprinting

  13. Stella protects maternal chromosomes from aberrant epigenetic modifications to ensure early embryogenesis.

  14. Chromocenter formation is impaired in Stella-null embryos.

  15. we propose that Dppa3 is involved in the Tet-mediated active demethylation process during reprogramming of primordial germ cells.

  16. PGC7 protects 5mC from Tet3-mediated conversion to 5hmC by binding to maternal chromatin containing dimethylated histone H3 lysine 9 (H3K9me2) in mice

  17. These Dppa3-MCM strains offer valuable opportunities to explore gene function in both loss-of-function and gain-of-function experiments at a variety of time points during germ cell development.

  18. DPPA3 is an essential factor for the production of functional oocytes through transcriptional repression and chromatin condensation.

  19. Data show that STELLA was found in both the nucleus and cytoplasm in a variety of cell types, both within and outside of the putative primordial germ cells (PGCs)trajectory.

  20. Data show that Stella is specifically expressed in preimplantation embryos and in the germline.

DPPA3 profil antigène

Profil protéine

This gene encodes a protein that in mice may function as a maternal factor during the preimplantation stage of development. In mice, this gene may play a role in transcriptional repression, cell division, and maintenance of cell pluripotentiality. In humans, related intronless loci are located on chromosomes 14 and X.

Gene names and symbols associated with DPPA3

  • developmental pluripotency associated 3 (DPPA3) anticorps
  • developmental pluripotency-associated 3 (Dppa3) anticorps
  • 2410075G02Rik anticorps
  • PCG7 anticorps
  • PGC7 anticorps
  • Stella anticorps

Protein level used designations for DPPA3

developmental pluripotency-associated protein 3 , stella , stella-related protein , developmental pluripotency associated 3 , compaction-associated protein 1 , primordial germ cell 7 , primordial germ cell protein 7

616433 Bos taurus
748273 Pan troglodytes
359787 Homo sapiens
73708 Mus musculus
297576 Rattus norvegicus
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