Filtrer les résultats:
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Gene names and symbols associated with FCAR
- Fc fragment of IgA receptor (FCAR) anticorps
- Fc fragment of IgA, receptor for (FCAR) anticorps
- CD89 anticorps
Protein level used designations for FCAR
IgA Fc receptor , immunoglobulin A Fc receptor , immunoglobulin alpha Fc receptor , Fc fragment of IgA, receptor for, isoform 7 , Fc alpha receptor