GTP Binding Protein 3 (Mitochondrial) (GTPBP3) Kits ELISA

This locus encodes a GTP-binding protein. De plus, nous expédions GTPBP3 Anticorps (34) et GTPBP3 Protéines (5) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
GTPBP3 290633 Q5PQQ1
GTPBP3 70359 Q923K4
GTPBP3 84705 Q969Y2
Comment commander chez anticorps-enligne
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Commandez enligne

Top GTPBP3 Kits ELISA sur

Showing 3 out of 6 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Livraison Prix Détails
Humain < 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests 11 to 18 Days
Souris < 46.9 pg/mL 78 pg/mL - 5000 pg/mL   96 Tests 11 to 18 Days
Rat < 46.9 pg/mL 78 pg/mL - 5000 pg/mL   96 Tests 11 to 18 Days

Plus Kits ELISA pour GTPBP3 partenaires d'interaction

Zebrafish GTP Binding Protein 3 (Mitochondrial) (GTPBP3) interaction partners

  1. defective expression of gtpbp3 related to tRNA modification alters the mitochondrial function and development of zebrafish

Mouse (Murine) GTP Binding Protein 3 (Mitochondrial) (GTPBP3) interaction partners

  1. These observations suggest that the mouse Gtpbp3 is an evolutionarily conserved mitochondrial GTP-binding protein involved in the tRNA modification.

Human GTP Binding Protein 3 (Mitochondrial) (GTPBP3) interaction partners

  1. Low GTPBP3 expression is associated with Mitochondrial diseases in neoplasms.

  2. Defects in the mitochondrial tRNA modification enzymes MTO1 and GTPBP3 promote different metabolic reprogramming through a HIF-PPARgamma-UCP2-AMPK axis.

  3. GTPBP3 defective expression is associated with an mitochondrial-tRNA hypomodification status.GTPBP3 plays a role in the regulation of UCP2 and MCP1 proteins through AMPK signaling.

  4. Results show that post-transcriptional expression of GTPBP3, MTO1 and TRMU genes is down-regulated, leading to mt-tRNA hypomodification and contributing to mitochondrial dysfunction in MELAS cybrids.

  5. Most individuals with GTPBP3 mutations developed neurological symptoms and MRI involvement of thalamus, putamen, and brainstem resembling Leigh syndrome.

  6. GTPBP3 localizes in the mitochondria and is a deafness-associated homolog of yeast MSS1.

  7. Phenotype of non-syndromic deafness associated with the mitochondrial A1555G mutation is modulated by mitochondrial RNA modifying enzymes MTO1 and GTPBP3.

  8. Data show that the two most abundant GTPBP3 isoforms exhibit moderate affinity for guanine nucleotides like their bacterial homologue, MnmE, although they hydrolyze GTP at a 100-fold lower rate.

GTPBP3 profil antigène

Antigen Summary

This locus encodes a GTP-binding protein. The encoded protein is localized to the mitochondria and may play a role in mitochondrial tRNA modification. Polymorphisms at this locus may be associated with severity of aminoglycoside-induced deafness, a disease associated with a mutation in the 12S rRNA. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene names and symbols associated with GTPBP3

  • GTP binding protein 3, mitochondrial (GTPBP3) anticorps
  • GTP binding protein 3 (Gtpbp3) anticorps
  • GTP binding protein 3, mitochondrial (gtpbp3) anticorps
  • 2410009F13Rik anticorps
  • AI607903 anticorps
  • GTPBG3 anticorps
  • GTPBP3 anticorps
  • MSS1 anticorps
  • MTGP1 anticorps
  • THDF1 anticorps
  • zgc:112394 anticorps

Protein level used designations for GTPBP3

GTP binding protein 3 (mitochondrial) , tRNA modification GTPase GTPBP3, mitochondrial , tRNA modification GTPase GTPBP3, mitochondrial-like , GTP-binding protein 3 , mitochondrial GTP-binding protein 1

484838 Canis lupus familiaris
539656 Bos taurus
100070158 Equus caballus
100392904 Callithrix jacchus
100474937 Ailuropoda melanoleuca
290633 Rattus norvegicus
553807 Danio rerio
70359 Mus musculus
84705 Homo sapiens
Fournisseurs de qualité sélectionnés pour GTPBP3 (GTPBP3) Kits ELISA
Avez-vous cherché autre chose?