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The protein encoded by IL27 is one of the subunits of a heterodimeric cytokine complex. De plus, nous expédions IL27 Anticorps (18) et et beaucoup plus de produits pour cette protéine.
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IFN-gamma (Montrer IFNG Kits ELISA) induces IL-30 production which suppresses IFN-gamma (Montrer IFNG Kits ELISA) mediated liver inflammation.
IL-27 signaling in Foxp3 (Montrer FOXP3 Kits ELISA)(+) Tregs essential for Tregs to control autoimmune inflammation in the central nervous system
this study indicates that IL-27 secreted by cervical carcinoma cells restricts the angiogenesis in a paracrine manner in the pathogenesis of cervical cancer
this study has revealed an important role of thymic dendritic cells-derived IL-27 in the regulation of the phenotypic maturation of CD4 (Montrer CD4 Kits ELISA)(+) single positive thymocytes.
TTP (Montrer ZFP36 Kits ELISA), encoded by Zfp36 (Montrer ZFP36 Kits ELISA), degrades p28 (Montrer GSTO1 Kits ELISA) to inhibit IL-27 production by macrophages and is thereby a negative regulator of the antitumour response.
these data infer that endopeptidase mediated gliadin degradation by macrophages and concomitant IL-27 production drive differentiation of splenic gliadin-specific Tr1-like cells in celiac disease
endogenous levels of IL-27 affected the oncogenic properties of mutant p53 (Montrer TP53 Kits ELISA) in vivo in a Li-Fraumeni mouse model. Lack of IL-27 signaling led to shortened survival times and increased incidence of osteosarcomas.
Interleukin-27 is upregulated centrally and peripherally after intracerebral hemorrhage. Interleukin-27 promotes the tissue-protecting functions of neutrophils via, at least partly, the induction of lactoferrin (Montrer LTF Kits ELISA).
Serum IL-27 levels and cardiac IL-27 mRNA expression were significantly increased after LPS injection compared with control specimens.
these findings highlight critical roles for IFN-gamma (Montrer IFNG Kits ELISA) and IL-27 in the mechanism of respiratory syncytial virus-induced exacerbation
IL-27 was down-regulated in the malignant Middle Cerebral Artery Infarction.
IL-27 may be involved in the development of coronary artery lesions in acute Kawasaki disease.
Hepatitis B virus infection can lead to overexpression of interleukin-27 gene in liver transplant patients.
IL-27 signaling (IL-27 and its receptor) may be involved in the pathogenesis of HIV infection and immune reconstitution in HIV/AIDS patients who underwent HAART. IL-27 may exert effects through regulating Th1 (Montrer TH1L Kits ELISA) / Th2 ratio.
This study provides additional evidence that IL-27 may contribute to autoimmune processes in MS patients.
this study shows that IL-27 regulates the adherence, proliferation, and migration of placenta-derived mesenchymal stromal cells and enhances their regulatory effects on Th1 (Montrer TH1L Kits ELISA) and Th2 subset generations
This study failed to find an association between common variants in the functional region of IL27 and coronary artery disease in a Chinese Han population
Data point out to a broad set of activities shared by IL-27 and IFN-gamma (Montrer IFNG Kits ELISA), which are dependent on the common activation of the STAT1 (Montrer STAT1 Kits ELISA) pathway. These data add further explanation to the anti-tumor activity of IL-27 and also to its dual role in immune regulation
The current meta-analysis suggests that IL-27 -964A/G polymorphism might enhance cancer risk. However, large-scale and well-designed studies are still needed to confirm the result of our meta-analysis
The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).
IL-27 p28 subunit
, IL-27 subunit alpha
, interleukin 30
, interleukin-27 subunit alpha