anti-Lecithin-Cholesterol Acyltransferase (LCAT) Anticorps

LCAT encodes the extracellular cholesterol esterifying enzyme, lecithin-cholesterol acyltransferase. De plus, nous expédions LCAT Kits (48) et LCAT Protéines (33) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
LCAT 3931 P04180
LCAT 16816 P16301
LCAT 24530  
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Top anti-LCAT Anticorps sur anticorps-enligne.fr

Showing 10 out of 116 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué WB <b>WB Suggested Anti-LCAT Antibody Titration: </b>5.0ug/ml<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$229.00
Détails
Humain Lapin Inconjugué WB 100 μg Connectez-vous pour afficher 4 to 6 Days
$240.00
Détails
Humain Lapin Inconjugué WB Anti-LCAT antibody, Western blotting Lane 1: Rat Brain Tissue Lysate Lane 2: U87 Cell Lysate Lane 3: HELA Cell Lysate Lane 4: SMMC Cell Lysate 100 μg Connectez-vous pour afficher 4 to 6 Days
$240.00
Détails
Humain Lapin Inconjugué FACS, IF, IHC (p), WB Western blot analysis of LCAT Antibody (Center) (ABIN653825) in K562 cell line lysates (35 µg/lane). LCAT (arrow) was detected using the purified polyclonal antibody. LCAT Antibody (Center) (ABIN653825) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Connectez-vous pour afficher 10 to 11 Days
$324.50
Détails
Humain Lapin Inconjugué EIA, FACS, IF, IHC (p), WB   0.4 mL Connectez-vous pour afficher 12 to 15 Days
$518.65
Détails
Humain Lapin Inconjugué ICC, IHC, WB Figure. DAB staining on IHC-P; Samples: Human Kidney Tissue. 100 μg Connectez-vous pour afficher 15 to 18 Days
$350.00
Détails
Boeuf (Vache) Lapin Inconjugué WB 100 μg Connectez-vous pour afficher 7 to 9 Days
$493.17
Détails
Boeuf (Vache) Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Humain Lapin Inconjugué ICC, IF, WB Western Blot: LCAT Antibody [NBP1-05950] - Analysis of plasma LCAT protein mass. Plasma samples (0.2ul) from four hA-I Tg mice, four hA-I Tg SR-BI -/- mice, a LCAT-/- mouse, and purified mouse LCAT were fractionated on SDS-PAGE, and LCAT was detected by Western blot analysis using rabbit antiserum against mouse LCAT. Immunocytochemistry/Immunofluorescence: LCAT Antibody [NBP1-05950] - The LCAT antibody was tested at a 1:500 dilution in HeLa cells against Dylight 488 (Green). Alpha-tubulin and nuclei were counterstained against Dylight 550 (Red) and DAPI (Blue). 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$444.19
Détails

LCAT Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-LCAT Anticorps mieux référencés

  1. Human Polyclonal LCAT Primary Antibody pour ELISA, WB - ABIN152886 : Furbee, Francone, Parks: In vivo contribution of LCAT to apolipoprotein B lipoprotein cholesteryl esters in LDL receptor and apolipoprotein E knockout mice. dans Journal of lipid research 2002 (PubMed)
    Show all 7 Pubmed References

  2. Human Polyclonal LCAT Primary Antibody pour ICC, IF - ABIN438375 : Lee, Badeau, Mulya, Boudyguina, Gebre, Smith, Parks: Functional LCAT deficiency in human apolipoprotein A-I transgenic, SR-BI knockout mice. dans Journal of lipid research 2007 (PubMed)
    Show all 3 Pubmed References

  3. Cow (Bovine) Polyclonal LCAT Primary Antibody pour WB - ABIN2776941 : Calabresi, Pisciotta, Costantin, Frigerio, Eberini, Alessandrini, Arca, Bon, Boscutti, Busnach, Frascà, Gesualdo, Gigante, Lupattelli, Montali, Pizzolitto, Rabbone, Rolleri, Ruotolo, Sampietro, Sessa, Vaudo, Cantafora, Veglia, Calandra, Bertolini, Frances: The molecular basis of lecithin:cholesterol acyltransferase deficiency syndromes: a comprehensive study of molecular and biochemical findings in 13 unrelated Italian families. dans Arteriosclerosis, thrombosis, and vascular biology 2005 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre LCAT partenaires d’interaction

Human Lecithin-Cholesterol Acyltransferase (LCAT) interaction partners

  1. data suggests a model wherein the active site of LCAT is shielded from soluble substrates by a dynamic lid until it interacts with HDL (Montrer HSD11B1 Anticorps) to allow transesterification to proceed

  2. Increased LCAT activity may be associated with increased formation of triglyceride rich lipoproteins, leading to a reduction in LDL particle size and atherosclerosis.

  3. Mapping the naturally occurring mutations onto the structure provides insight into how they may affect LCAT enzymatic activity.

  4. Report slightly reduction in LCAT that would probably reflect a delay in reverse cholesterol transport occurring in MetS (Montrer ETV3 Anticorps).

  5. rs5923 polymorphism is not associated with low high-density lipoprotein cholesterol(HDL (Montrer HSD11B1 Anticorps)-C)levels in Iranian population

  6. increased cholesterol esterification by LCAT is atheroprotective

  7. The data indicate that this novel apoA-I (Montrer APOA1 Anticorps) missense is associated with markedly decreased levels of HDL (Montrer HSD11B1 Anticorps) cholesterol and very large alpha-1 HDL (Montrer HSD11B1 Anticorps), as well as decreased serum cellular cholesterol efflux and LCAT activity

  8. A robust all-atom model for LCAT generated by homology modeling

  9. This study investigated how the natural LCAT[T147I] and LCAT[P274S] mutations affect the pathway of biogenesis of high-density lipoproteins.

  10. A synonymous H287H mutation in the coding region of exon 6 of the lecithin cholesterol acyltransferase gene was observed in an individual with HDLC levels of 75 mg/dl.

Mouse (Murine) Lecithin-Cholesterol Acyltransferase (LCAT) interaction partners

  1. Taken together, these results suggest that apoE (Montrer APOE Anticorps)-containing discoidal HDLs (Montrer CSF1R Anticorps) do not require LCAT-dependent maturation to mediate efficient Abeta (Montrer APP Anticorps) clearance

  2. increased cholesterol esterification by LCAT is atheroprotective

  3. Gene transfer of WT LCAT in LCAT(-/-) mice increased 11.8-fold the plasma cholesterol, whereas the LCAT[T147I] and LCAT[P274S] mutants caused a 5.2- and 2.9-fold increase, respectively.

  4. DYRK1A (Montrer DYRK1A Anticorps) overexpression decreases plasma lecithin:cholesterol acyltransferase activity and apolipoprotein A-I (Montrer APOA1 Anticorps) levels.

  5. adrenal glucocorticoid function in LCAT knockout (KO) mice

  6. a novel function of apoA-IV (Montrer APOA4 Anticorps) in the biogenesis of discrete HDL (Montrer HSD11B1 Anticorps)-A-IV particles with the participation of ABCA1 (Montrer ABCA1 Anticorps) and LCAT

  7. Studies suggest that absence of lecithin cholesterol acyltransferase (LCAT) may protect against insulin (Montrer INS Anticorps) resistance, diabetes and obesity.

  8. Data show that LCAT activity was significantly higher in long chain base biosynthesis protein 2 (Sptlc2 (Montrer SPTLC2 Anticorps))+/- and sphingomyelin synthase 2 (Sms2 (Montrer SGMS2 Anticorps))-/- mice, but markedly lower in ApoE (Montrer APOE Anticorps)-/- and Ldlr (Montrer LDLR Anticorps)-/- mice.

  9. LCAT deficiency confers gender-specific protection against diet-induced obesity and insulin (Montrer INS Anticorps) resistance at least in part through regulation in UPR, white adipose tissue adipogenesis, and brown adipocyte partitioning

  10. Oxidative stress is markedly elevated in lecithin:cholesterol acyltransferase-deficient mice and is paradoxically reversed in the apolipoprotein E (Montrer APOE Anticorps) knockout background in association with a reduction in atherosclerosis

Rabbit Lecithin-Cholesterol Acyltransferase (LCAT) interaction partners

  1. LCAT cholesterol esterification is associated with the increase of ApoE (Montrer APOE Anticorps)/ApoA-I (Montrer APOA1 Anticorps) ratio during atherosclerosis progression in rabbit.

Pig (Porcine) Lecithin-Cholesterol Acyltransferase (LCAT) interaction partners

  1. The 1,434 bp mRNA sequence of porcine LCAT including the full coding region and encoding a protein of 472 amino acids, was obtained.

LCAT profil antigène

Profil protéine

This gene encodes the extracellular cholesterol esterifying enzyme, lecithin-cholesterol acyltransferase. The esterification of cholesterol is required for cholesterol transport. Mutations in this gene have been found to cause fish-eye disease as well as LCAT deficiency.

Gene names and symbols associated with LCAT

  • lecithin-cholesterol acyltransferase (LCAT) anticorps
  • lecithin cholesterol acyltransferase (Lcat) anticorps
  • lecithin-cholesterol acyltransferase L homeolog (lcat.L) anticorps
  • lecithin-cholesterol acyltransferase (lcat) anticorps
  • solute carrier family 12 member 4 (SLC12A4) anticorps
  • lecithin-cholesterol acyltransferase (Lcat) anticorps
  • fragile site, aphidicolin type, common, fra(13)(q13.2) (FRA13A) anticorps
  • AI046659 anticorps
  • D8Wsu61e anticorps
  • LCAT anticorps
  • MGC82035 anticorps
  • MGC88964 anticorps

Protein level used designations for LCAT

phosphatidylcholine-sterol acyltransferase , phospholipid-cholesterol acyltransferase , lecithin-cholesterol acyltransferase Lcat , lecithin-cholesterol acyltransferase , lecithin cholesterol acyltransferase , Lecithin-cholesterol acyltransferase

GENE ID SPECIES
3931 Homo sapiens
16816 Mus musculus
396136 Gallus gallus
447501 Xenopus laevis
448241 Xenopus (Silurana) tropicalis
479680 Canis lupus familiaris
510960 Bos taurus
743056 Pan troglodytes
100008978 Oryctolagus cuniculus
100126664 Papio anubis
100302343 Ovis aries
100303723 Sus scrofa
100389625 Callithrix jacchus
100469078 Ailuropoda melanoleuca
100528492 Ictalurus punctatus
24530 Rattus norvegicus
100053753 Equus caballus
100727686 Cavia porcellus
793137 Danio rerio
Fournisseurs de qualité sélectionnés pour anti-LCAT (LCAT) Anticorps
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