Profil protéine

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with LILRB4

• leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 (LILRB4) anticorps
• leukocyte immunoglobulin like receptor B4 (LILRB4) anticorps
• leukocyte immunoglobulin-like receptor, subfamily B, member 4A (Lilrb4a) anticorps

• CD85K anticorps
• gp49 anticorps
• Gp49b anticorps
• HM18 anticorps
• ILT-3 anticorps
• Afficher tous les alias de synonymes
• ILT3 anticorps
• LIR-5 anticorps
• LIR5 anticorps

Protein level used designations for LILRB4

leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 , CD85 antigen-like family member K , immunoglobulin-like transcript 3 , leukocyte immunoglobulin-like receptor 5 , leukocyte immunoglobulin-like receptor subfamily B member 4 , monocyte inhibitory receptor HM18 , glycoprotein 49 B , mast cell surface glycoprotein Gp49B