anti-MAP/microtubule Affinity-Regulating Kinase 1 (MARK1) Anticorps

Serine/threonine-protein kinase involved in cell polarity and microtubule dynamics regulation. De plus, nous expédions MARK1 Protéines (7) et MARK1 Kits (6) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
MARK1 226778 Q8VHJ5
MARK1 117016 O08678
MARK1 4139 Q9P0L2
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Top anti-MARK1 Anticorps sur anticorps-enligne.fr

Showing 10 out of 148 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué IC, IF, IHC, WB Immunofluorescent analysis of MARK staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of MARK staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Connectez-vous pour afficher 13 to 14 Days
$487.50
Détails
Souris Chèvre Inconjugué ELISA   100 μg Connectez-vous pour afficher 6 to 7 Days
$296.69
Détails
Humain Lapin Inconjugué ELISA, WB Western blot analysis of extracts from HeLa cells, using MARK Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Connectez-vous pour afficher 2 to 3 Days
$302.50
Détails
Humain Lapin Inconjugué IHC (p), WB The anti-MARK1 N-term Pab (ABIN391219) is used in Western blot to detect MARK1 in P7 mouse whole brain lysate (60 ug). 1:250 dilution of anti-MARK1 pab was used. Data and protocol kindly provided by DR. Shengli Zhao, M.D., Ph.D. of Duke University Medical Center. Formalin-fixed and paraffin-embedded human brain tissue reacted with MARK1 Antibody (N-term) (ABIN391219), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails
Humain Lapin Inconjugué WB The anti-MARK1 C-term Pab (7144b) is used in Western blot to detect MARK1 in, from left to right, Hela, T47D, and mouse brain cell line/ tissue lysate. 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails
Humain Lapin Inconjugué WB Mouse Mark1 Antibody (C-term) (ABIN658190) western blot analysis in mouse brain tissue lysates (35 µg/lane). This demonstrates the Mark1 antibody detected the Mark1 protein (arrow). 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails
Humain Lapin Inconjugué EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human brain tissue reacted with MARK1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. The anti-MARK1 N-term Pab is used in Western blot to detect MARK1 in P7 mouse whole brain lysate (60 ug). 1:250 dilution of anti-MARK1 pab was used. 0.4 mL Connectez-vous pour afficher 6 to 8 Days
$390.50
Détails
Humain Lapin Inconjugué EIA, WB The anti-MARK1 C-term Pab is used in Western blot to detect MARK1 in, from left to right, Hela, T47D, and mouse brain cell line/ tissue lysate. 0.4 mL Connectez-vous pour afficher 6 to 8 Days
$390.50
Détails
Roussette (Chauve-souris) Lapin Inconjugué IHC, IHC (p) Anti-MARK1 antibody  ABIN1049038 IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-MARK1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Connectez-vous pour afficher 11 to 14 Days
$484.00
Détails
Humain Lapin Inconjugué IHC (p), WB MARK Antibody (S658) (ABIN652301) western blot analysis in T47D cell line lysates (35 µg/lane).This demonstrates the MARK antibody detected the MARK protein (arrow). MARK Antibody (C-term) (ABIN652301)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Connectez-vous pour afficher 10 to 11 Days
$335.50
Détails

anti-MARK1 Anticorps mieux référencés

  1. Human Polyclonal MARK1 Primary Antibody pour IHC (p), WB - ABIN391219 : Drewes, Ebneth, Preuss, Mandelkow, Mandelkow: MARK, a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption. dans Cell 1997 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal MARK1 Primary Antibody pour WB - ABIN391220 : Hezel, Gurumurthy, Granot, Swisa, Chu, Bailey, Dor, Bardeesy, Depinho: Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms. dans Molecular and cellular biology 2008 (PubMed)
    Show all 2 Pubmed References

Plus d’anticorps contre MARK1 partenaires d’interaction

Mouse (Murine) MAP/microtubule Affinity-Regulating Kinase 1 (MARK1) interaction partners

  1. In vitro kinase assays and metabolic-labeling experiments in living cells confirmed MARK1 as an LRRK2 substrate. Moreover, we also showed that LRRK2 and MARK1 are interacting in eukaryotic cells.

  2. Overexpression and silencing of MARK1 resulted in significantly shorter dendrite length in mouse neocortical neurons and modified dendritic transport speed.

Human MAP/microtubule Affinity-Regulating Kinase 1 (MARK1) interaction partners

  1. Low MARK1 is associated with cervical cancer.

  2. Molecular determinants of KA1 (Montrer GRIK4 Anticorps) domain-mediated autoinhibition and phospholipid activation of MARK1 kinase have been described.

  3. the positioning of MARK/Par-1 (Montrer MARK2 Anticorps) at the crosstalk of regulating cytoskeletal dynamics allows its participation in neuronal polarity decisions. [review]

  4. LKB1 (Montrer STK11 Anticorps) acts through its substrates of the microtubule affinity-regulating kinase family to regulate the localization of the polarity determinant Scribble (Montrer SCRIB Anticorps) and the activity of the core Hippo kinases

  5. In the Australian GWAS, the SNP rs7530302 near MARK1 on chromosome 1 (p=1.90 x 10(-9) achieved genomewide significance for comorbid AD/ND.

  6. analysis of variations in the catalytic and ubiquitin-associated domains of microtubule-associated protein/microtubule affinity regulating kinase (MARK) 1 and MARK2 (Montrer MARK2 Anticorps)

  7. MARK1 was overexpressed in a prefrontal region in the brains of patients with Autism spectrum disorders.

MARK1 profil antigène

Profil protéine

Serine/threonine-protein kinase involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2, MAP4 and MAPT/TAU. Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3) (By similarity).

Gene names and symbols associated with MARK1

  • MAP/microtubule affinity-regulating kinase 1 S homeolog (mark1.S) anticorps
  • microtubule affinity regulating kinase 1 (MARK1) anticorps
  • MAP/microtubule affinity-regulating kinase 1 (mark1) anticorps
  • microtubule affinity regulating kinase 1 (mark1) anticorps
  • MAP/microtubule affinity regulating kinase 1 (Mark1) anticorps
  • microtubule affinity regulating kinase 1 (Mark1) anticorps
  • AW491150 anticorps
  • B930025N23Rik anticorps
  • Emk3 anticorps
  • MARK anticorps
  • MARK1 anticorps
  • MGC80341 anticorps
  • mKIAA1477 anticorps
  • mPar-1c anticorps
  • Par-1c anticorps
  • Par1c anticorps

Protein level used designations for MARK1

MAP/microtubule affinity-regulating kinase 1 , chemokine CCL-CUc , serine/threonine-protein kinase MARK1 , serine/threonine-protein kinase MARK1-like , ELKL motif serine-threonine protein kinase 3 , ELKL motif serine/threonine-protein kinase 3 , PAR1 homolog c

GENE ID SPECIES
432201 Xenopus laevis
469683 Pan troglodytes
100003170 Danio rerio
100456064 Pongo abelii
100559635 Anolis carolinensis
226778 Mus musculus
117016 Rattus norvegicus
4139 Homo sapiens
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