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May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. De plus, nous expédions Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) Kits (16) et Melanoma Antigen Family A, 1 (Directs Expression of Antigen MZ2-E) Protéines (8) et beaucoup plus de produits pour cette protéine.
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MAGE (Montrer MAGEB10 Anticorps)-A expression in blood or bone marrow at tumor surgery is an independent predictor of survival in resected non-small cell lung cancer
Authors revealed a novel interaction between MAGEA1 and the intracellular segment of NOTCH1 receptor (NICD1). MAGEA1 reduced NICD1's stability by promoting the ubiquitin modification of NICD1.
In patients with Colon cancer, the expression of MAGE (Montrer MAGEB10 Anticorps)-A(1-6) gene was associated with a poor prognosis.
MAGEA1 was expression in 15% of synovial sarcomas and was not associated with prognosis.
Data show that overall survival (OS) was significantly lower for patients expressing pan (Montrer SUPT6H Anticorps)-MAGE (Montrer MAGEB10 Anticorps) or MAGE (Montrer MAGEB10 Anticorps)-A1/A3/A4 in both independent cohorts.
These data demonstrate that MAGE (Montrer MAGEB10 Anticorps)-A1-, MAGE-A3 (Montrer MAGEA3 Anticorps)-, and NY-ESO-1 (Montrer CTAG1B Anticorps)-specific T cells with antigen-specific cytotoxicity can be cultured from healthy donors and patient-derived cells making adoptive immunotherapy with these cytotoxic T lymphocyte feasible.
up-regulation of MAGE (Montrer MAGEB10 Anticorps)-A1 dramatically promoted proliferation, migration, and invasion of human melanoma cell lines in vitro
The overall survival of laryngeal squamous cell carcinoma patients with positive MAGE-A1, MAGE-A9, or MAGE-A11 expression was lower than the patients without MAGE-A1, MAGE-A9, or MAGE-A11 expression.
MAGE (Montrer MAGEB10 Anticorps)-A is more highly expressed than NY-ESO-1 (Montrer CTAG1B Anticorps) in a majority of human malignancies
TRIM31 (Montrer TRIM31 Anticorps) directly binds to NSE4, suggesting the existence of a TRIM31 (Montrer TRIM31 Anticorps)-MAGEA1-NSE4 complex reminiscent of the NSE1 (Montrer FAM84A Anticorps)-NSE3 (Montrer NDNL2 Anticorps)-NSE4 trimer.
results indicate that the fusion of Hsp70 (Montrer HSP70 Anticorps) to Mage (Montrer MAGEB10 Anticorps)-a1 can enhance immune responses and anti-tumor effects against Mage (Montrer MAGEB10 Anticorps)-a1-expressing tumors
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.
, antigen MZ2-E
, cancer/testis antigen 1.1
, cancer/testis antigen family 1, member 1
, melanoma antigen MAGE-1
, melanoma antigen family A 1
, melanoma-associated antigen 1
, melanoma-associated antigen MZ2-E
, melanoma antigen family A, 1