NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 5, 13kDa Protéines (NDUFA5)

The human NDUFA5 gene codes for the B13 subunit of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. De plus, nous expédions NDUFA5 Anticorps (39) et et beaucoup plus de produits pour cette protéine.

afficher tous les protéines Gène GeneID UniProt
Rat NDUFA5 NDUFA5 25488 Q63362
NDUFA5 4698 Q16718
NDUFA5 68202 Q9CPP6
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Showing 10 out of 11 products:

Catalogue No. Origin Source Conjugué Images Quantité Fournisseur Livraison Prix Détails
Escherichia coli (E. coli) Humain His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 30 to 35 Days
$5,465.26
Détails
Escherichia coli (E. coli) Souris His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Connectez-vous pour afficher 30 to 35 Days
$5,465.26
Détails
Wheat germ Humain GST tag 10 μg Connectez-vous pour afficher 11 to 12 Days
$414.29
Détails
Escherichia coli (E. coli) Humain His tag 100 μg Connectez-vous pour afficher 15 to 19 Days
$953.85
Détails
HEK-293 Cells Humain Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Connectez-vous pour afficher Disponible
$814.00
Détails
Levure Pongo pygmaeus His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$2,222.00
Détails
Levure Orang-Utan His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$2,222.00
Détails
Levure Cynomolgus His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$2,222.00
Détails
Levure Chimpanzé His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$2,222.00
Détails
Levure Boeuf (Vache) His tag   1 mg Connectez-vous pour afficher 60 to 71 Days
$2,222.00
Détails

NDUFA5 Protéines protéines par origine et source

Origin Exprimée danse Conjugué
Human , ,
, ,
Mouse (Murine)

Plus protéines pour NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 5, 13kDa (NDUFA5) partenaires d'interaction

Human NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 5, 13kDa (NDUFA5) interaction partners

  1. NDUFA3 (Montrer NDUFA3 Protéines), NDUFA5 and NDUFA12 (Montrer NDUFA12 Protéines) supernumerary subunits are necessary for complex I activity and biogenesis.

Mouse (Murine) NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 5, 13kDa (NDUFA5) interaction partners

  1. At the age of 11 months, mice with a central nervous system knockout of Ndufa5 (Ndufa5 CNS-KO) showed lethargy and loss of motor skills. In these mice cortices, the levels of NDUFA5 protein were reduced to 25% of controls. Fully assembled complex I (CI) levels were also greatly reduced in cortex and CI activity in homogenates was reduced to 60% of controls.

  2. The real-time RT-PCR analysis revealed that the expressions of the NDUFA5 mRNA, but not the ZNF9 (Montrer CNBP Protéines) mRNA level, were significantly up-regulated in all the tested cell lines derived from HPV-positive cervical cancer, HeLa, SW576, and CaSKi.

Profil protéine NDUFA5

Profil protéine

The human NDUFA5 gene codes for the B13 subunit of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. The high degree of conservation of NDUFA5 extending to plants and fungi indicates its functional significance in the enzyme complex. The protein localizes to the inner mitochondrial membrane as part of the 7 component-containing, water soluble 'iron-sulfur protein' (IP) fraction of complex I, although its specific role is unknown. It is assumed to undergo post-translational removal of the initiator methionine and N-acetylation of the next amino acid. The predicted secondary structure is primarily alpha helix, but the carboxy-terminal half of the protein has high potential to adopt a coiled-coil form. The amino-terminal part contains a putative beta sheet rich in hydrophobic amino acids that may serve as mitochondrial import signal. Related pseudogenes have also been identified on four other chromosomes.

Gene names and symbols associated with NDUFA5

  • NADH:ubiquinone oxidoreductase subunit A5 (Ndufa5)
  • NADH:ubiquinone oxidoreductase subunit A5 (NDUFA5)
  • NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 (Ndufa5)
  • 2900002J19Rik Protéine
  • B13 Protéine
  • CI-13kB Protéine
  • CI-13KD-B Protéine
  • NADHUO Protéine
  • NUFM Protéine
  • UQOR13 Protéine

Protein level used designations for NDUFA5

CI-13kD-B , NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 , NADH ubiquinone oxidoreductase subunit B13 , NADH-ubiquinone oxidoreductase 13 kDa-B subunit , complex I subunit B13 , complex I-13kD-B , Complex I-13KD-B , NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa , complex I 13kDa subunit B , type I dehydrogenase , ubiquinone reductase

GENE ID SPECIES
25488 Rattus norvegicus
4698 Homo sapiens
68202 Mus musculus
327714 Bos taurus
100172232 Pongo abelii
463686 Pan troglodytes
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