anti-OTU Domain Containing 7B (OTUD7B) Anticorps

Has deubiquitinating activity that is directed towards 'Lys-48' or 'Lys-63'-linked polyubiquitin chains. De plus, nous expédions OTUD7B Protéines (7) et et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
OTUD7B 56957 Q6GQQ9
OTUD7B 229603  
OTUD7B 310677  
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Top anti-OTUD7B Anticorps sur anticorps-enligne.fr

Showing 10 out of 41 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB WB Suggested Anti-OTUD7B Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  293T cell lysate Rabbit Anti-OTUD7B Antibody    Formalin Fixed Paraffin Embedded Tissue: Human Adult heart  Observed Staining: Cytoplasmic Primary Antibody Concentration: 1:600 Secondary Antibody: Donkey anti-Rabbit-Cy2/3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 – 2.0 sec Protocol located in Reviews and Data. 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué WB WB Suggested Anti-ZA20D1 Antibody Titration:  1.25ug/ml  ELISA Titer:  1:312500  Positive Control:  Daudi cell lysate OTUD7B is supported by BioGPS gene expression data to be expressed in Daudi 100 μL Connectez-vous pour afficher 2 to 3 Days
$229.00
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 100 μg Connectez-vous pour afficher 11 to 14 Days
$493.17
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: OTUD7B/Cezanne/ZA20D1 Antibody [NBP1-88095] - Immunohistochemical staining of human rectum shows strong cytoplasmic and nuclear positivity in glandular cells. Immunocytochemistry/Immunofluorescence: OTUD7B/Cezanne/ZA20D1 Antibody [NBP1-88095] - Staining of human cell line U-251MG shows positivity in cytoskeleton (microtubules). 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$494.38
Détails
Roussette (Chauve-souris) Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 11 to 14 Days
$551.83
Détails
Humain Lapin Inconjugué IHC, WB Western blot analysis of extracts of Jurkat cells, using OTUD7B antibody. ABIN6273062 at 1/100 staining Mouse liver tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. 100 μL Connectez-vous pour afficher 11 to 12 Days
$390.77
Détails
Humain Souris Inconjugué ELISA, IHC, IHC (p), WB Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-OTUD7B antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg Connectez-vous pour afficher 11 to 14 Days
$550.00
Détails
Humain Souris Inconjugué IF, IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to OTUD7B on formalin-fixed paraffin-embedded human endometrium. [antibody concentration 3 ug/ml] Detection limit for recombinant GST tagged OTUD7B is 0.3 ng/ml as a capture antibody. 100 μg Connectez-vous pour afficher 11 to 12 Days
$440.00
Détails
Humain Souris Inconjugué EIA, IHC (p), WB 50 μg Connectez-vous pour afficher 6 to 8 Days
$445.50
Détails
Chien Lapin Inconjugué ELISA, WB 100 μg Connectez-vous pour afficher 2 to 3 Days
$446.88
Détails

Plus d’anticorps contre OTUD7B partenaires d’interaction

Human OTU Domain Containing 7B (OTUD7B) interaction partners

  1. Study demonstrated that the N-terminal UBA domain is crucial for the function of Cezanne during NF-kappaB activation. Cezanne is recognized and recruited into activated TNFR complex by specifically binding to polyubiquitinated signaling proteins after TNF stimulation through its N-terminal polyubiquitin binding site.

  2. Cezanne may be a novel antioncogene that has a pivotal role in the invasion of hepatocellular carcinoma and contribute to the selection of patients who may benefit from adjuvant transcatheter arterial chemoembolization to prevent recurrence.

  3. TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling

  4. Findings indicated both cezanne-1 and IGF1R expressions were negative independent predictive factors for the prognosis of lung adenocarcinoma, respectively. There was a close positive interrelationship between cezanne-1 and IGF1R expression.

  5. expression of OTUD7B and NIK were negatively correlated in non-small cell lung cancer tumor samples. The higher expression of OTUD7B was associated with smaller tumor size, less lymph node metastasis and earlier TNM stage. the high expression of OTUD7B was associated with good prognosis of NSCLC patients, and a high OTUD7B/low NIK index can predict even better prognosis. also, OTUD7B is an independent markers of survival.

  6. crystal structures of Cezanne alone and in complex with monoubiquitin and Lys11-linked diubiquitin, in combination with hydrogen-deuterium exchange mass spectrometry, enable a reconstruction of the enzymatic cycle in great detail

  7. these data reveal a novel mechanism for the regulation of the expression of HIF2a, demonstrating that the HIF2a promoter is regulated by E2F1 directly and that Cezanne regulates HIF2a expression through control of E2F1 levels

  8. Taken together, these results suggest that hepatitis C virus NS5A protein interacts with OTUD7B, thereby modulating its deubiquitinase activity.

  9. Cezanne has a pivotal role in tumor progression and prognosis, and may act as a potential prognostic biomarker for survival in hepatocellular carcinoma patients.

  10. data suggest that Cezanne is essential for HIF-1alpha protein stability and that loss of Cezanne stimulates HIF-1alpha degradation via proteasome-independent routes, possibly through chaperone-mediated autophagy.

  11. Genome wide association study shows evidence of association between mammographic density and SNPs in high linkage disequilibrium with rs11205277, rs11205303 in gene MTMR11 and rs67807996 in gene OTUD7B.

  12. Inflammatory responses to ischemia are controlled by a balance between TRAF6 ubiquitination and deubiquitination, and Cezanne is a key regulator of this process.

  13. identified a deubiquitinating enzyme, Cezanne-1, that opposes receptor degradation and enhances EGFR signaling

  14. There is an excessive inflammatory response but insufficient up-regulation of A20 expression in inflammatory bowel disease patients.

  15. DJ-1 enhances cell survival through the binding of Cezanne, a negative regulator of NF-kappaB.

  16. Cezanne is identified as the first deubiquitinase with Lys11-linkage preference.

  17. cleaves ubiquitin from proteins

  18. Cezanne forms a novel negative feedback loop in pro-inflammatory signaling and that it suppresses NF-kappaB activation by targeting RIP1 signaling intermediaries for deubiquitination

  19. H(2)O(2) prolongs NF-kappaB activation in co-stimulated cells by suppressing the negative regulatory functions of Cezanne and IkappaBalpha.

Mouse (Murine) OTU Domain Containing 7B (OTUD7B) interaction partners

  1. Cezanne may be a novel antioncogene that has a pivotal role in the invasion of hepatocellular carcinoma.

  2. TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling

  3. These findings establish Otud7b as a positive regulator of T cell receptor-proximal signaling and T cell activation, highlighting the importance of deubiquitination in regulating Zap70 function.

  4. Inflammatory responses to ischemia are controlled by a balance between ubiquitination and deubiquitination, and Cezanne is a key regulator of this process.

  5. findings establish OTUD7B as a crucial regulator of signal-induced non-canonical NF-kappaB activation and indicate a mechanism of immune regulation that involves OTUD7B-mediated deubiquitination and stabilization of TRAF3

  6. DJ-1 enhances cell survival through the binding of Cezanne, a negative regulator of NF-kappaB.

OTUD7B profil antigène

Profil protéine

Has deubiquitinating activity that is directed towards 'Lys-48' or 'Lys-63'-linked polyubiquitin chains. Hydrolyzes both linear and branched forms of polyubiquitin. Negative regulator of nuclear factor NF-kappa-B.

Gene names and symbols associated with OTUD7B

  • OTU deubiquitinase 7B (OTUD7B) anticorps
  • OTU deubiquitinase 7B (otud7b) anticorps
  • OTU domain containing 7B (Otud7b) anticorps
  • OTU deubiquitinase 7B (Otud7b) anticorps
  • 2900060B22Rik anticorps
  • 4930463P07Rik anticorps
  • AI462125 anticorps
  • CEZANNE anticorps
  • OTUD7B anticorps
  • RGD1308111 anticorps
  • Trabid2 anticorps
  • Za20d1 anticorps
  • zgc:152772 anticorps

Protein level used designations for OTUD7B

OTU domain containing 7B , zinc finger protein Cezanne , OTU domain-containing protein 7B , zinc finger, A20 domain containing 1 , cellular zinc finger anti-NF-kappa-B protein , cellular zinc finger anti-NF-kappaB Cezanne , zinc finger A20 domain-containing protein 1 , TRAF binding domain containing 2

GENE ID SPECIES
705774 Macaca mulatta
777637 Danio rerio
779455 Xenopus (Silurana) tropicalis
749087 Pan troglodytes
426041 Gallus gallus
100014166 Monodelphis domestica
100054396 Equus caballus
100446150 Pongo abelii
100464376 Ailuropoda melanoleuca
100551488 Meleagris gallopavo
100597721 Nomascus leucogenys
56957 Homo sapiens
229603 Mus musculus
483178 Canis lupus familiaris
525579 Bos taurus
310677 Rattus norvegicus
Fournisseurs de qualité sélectionnés pour anti-OTUD7B (OTUD7B) Anticorps
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