anti-SHANK-Associated RH Domain Interacting Protein (SHARPIN) Anticorps

directly interacts with the ankyrin repeats of Shank; may be involved in regulating the function of Shank. De plus, nous expédions SHARPIN Kits (7) et et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
SHARPIN 106025 Q91WA6
SHARPIN 81858 Q9H0F6
SHARPIN 81859 Q9EQL9
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Top anti-SHARPIN Anticorps sur anticorps-enligne.fr

Showing 10 out of 65 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué WB Host: Rabbit Target Name: CHAD Sample Type: Human Adult Placenta Antibody Dilution: 1.0ug/ml WB Suggested Anti-SHARPIN Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Hela cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: SHARPIN Antibody [NBP1-92386] - Staining of human colon shows strong cytoplasmic positivity in glandular cells. Immunocytochemistry/Immunofluorescence: SHARPIN Antibody [NBP1-92386] - Staining of human cell line MCF7 shows positivity in nucleus & cytoplasm. 0.1 mL Connectez-vous pour afficher 10 to 13 Days
$494.38
Détails
Humain Lapin Inconjugué WB 50 μg Connectez-vous pour afficher 11 to 14 Days
$551.83
Détails
Humain Lapin Inconjugué IHC, WB ABIN6272851 at 1/100 staining Mouse colon tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. Western blot analysis of extracts of Raji cells, using SHARPIN antibody. 100 μL Connectez-vous pour afficher 11 to 12 Days
$390.77
Détails
Humain Lapin Inconjugué WB SHARPIN Antibody (Center)  western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the SHARPIN antibody detected the SHARPIN protein (arrow). 400 μL Connectez-vous pour afficher 10 to 11 Days
$385.00
Détails
Humain Lapin Inconjugué WB Western blot analysis in mouse testis tissue lysates (35ug/lane). 400 μL Connectez-vous pour afficher 2 to 3 Days
$515.63
Détails
Humain Lapin Inconjugué WB Western Blot: SHARPIN Antibody [NBP1-79754] - Sample Type: Human Adult Placenta Antibody Dilution: 1.0 ug/ml Western Blot: SHARPIN Antibody [NBP1-79754] - Titration: 0.2-1 ug/ml, Positive Control: Hela cell lysate. 100 μL Connectez-vous pour afficher 8 to 11 Days
$488.73
Détails
Humain Lapin Inconjugué WB Western blot analysis of extracts of various cell lines, using SHARPIN antibody. 200 μL Connectez-vous pour afficher 12 to 14 Days
$438.90
Détails
Humain Souris Inconjugué ELISA, WB Western Blot detection against Immunogen (36.89 KDa) . 50 μL Connectez-vous pour afficher 11 to 12 Days
$305.71
Détails
Humain Lapin Alexa Fluor 594 IF (p)   100 μL Connectez-vous pour afficher 14 to 21 Days
$416.90
Détails

Plus d’anticorps contre SHARPIN partenaires d’interaction

Human SHANK-Associated RH Domain Interacting Protein (SHARPIN) interaction partners

  1. Sharpin-Arp2/3 interaction promotes lamellipodium formation.

  2. The binding of SHARPIN or HOIL-1L facilitates the E2 loading of HOIP.

  3. SIPL1 contributes to promote resistance to tamoxifen in Breast cancer cells through both AKT and NF-kappaB actions.

  4. the present study found that loss of the NEMO-SHARPIN interaction impaired recruitment of truncated NEMO forms into punctuate structures that are transiently formed on cell stimulation and thus led to a defect in linear ubiquitination

  5. LUBAC components control TLR3-mediated innate immunity, thereby preventing development of immunodeficiency and autoinflammation.

  6. Overexpression of SHARPIN in Prostate cancer cells promoted cell growth and reduced apoptosis through NF-kB/ERK/Akt pathway and apoptosis-associated proteins. SHARPIN enhances the metastasis of prostate cancer and impair patient survivals.

  7. Our study firstly identifies the role of SHARPIN in promoting wild-type P53 degradation and correlates with poor prognosis in P53 wild-type breast cancer.

  8. Data show that SHANK-associated RH domain interacting protein (SHARPIN) gene expression in breast cancer patients predicts clinical outcomes.

  9. the roles of SHARPIN in inhibiting integrin activity and supporting linear ubiquitination are (molecularly) distinct.

  10. progesterone significantly reduced SIPL1 mRNA and protein expression in MCF7 cells. As progesterone enhances breast cancer tumorigenesis in context dependent manner, inhibition of SIPL1 expression may contribute to progesterone's non-tumorigenic function

  11. SIPL1 binds PTEN and enhances PTEN polyubiquitination.

  12. Sharpin deficiency sensitized primary murine keratinocytes, human keratinocytes, and mouse embryonic fibroblasts to TNF-induced apoptosis.

  13. SIPL1 promotes AKT activation by decreasing the amount of PTEN protein in CHO-K1 cells.

  14. SHARPIN controls lymphocyte migration by endogenously maintaining LFA-1 inactive to allow adjustable detachment of the uropods in polarized cells.

  15. crystals of SHARPIN belonged to the primitive tetragonal space group P4(3)2(1)2, with unit-cell parameters a = b = 61.55, c = 222.81 A

  16. the crystal structure of the N-terminal portion of SHARPIN, which adopts the highly conserved pleckstrin homology superfold that is often used as a scaffold to create protein interaction modules

  17. SHARPIN inhibits the critical switching of beta1-integrins from inactive to active conformations.

  18. SHARPIN is an additional component of LUBAC; SHARPIN-containing complexes can linearly ubiquitinate NEMO and activated NF-kappaB

  19. Data report the identification of the related proteins Sipl1 (Shank-interacting protein-like 1) and Rbck1 (RBCC protein interacting with PKC1) as novel interaction partners of Eya1.

  20. Suggest that Sharpin is not an inert scaffold protein, but may play tumor-associated roles during cancer biogenesis.

SHARPIN profil antigène

Profil protéine

directly interacts with the ankyrin repeats of Shank; may be involved in regulating the function of Shank

Gene names and symbols associated with SHARPIN

  • SHANK-associated RH domain interacting protein (Sharpin) anticorps
  • SHANK associated RH domain interactor (SHARPIN) anticorps
  • SHANK-associated RH domain interactor (Sharpin) anticorps
  • 0610041B22Rik anticorps
  • AW121341 anticorps
  • Conneck1 anticorps
  • cpdm anticorps
  • RBCKL1 anticorps
  • SIPL1 anticorps

Protein level used designations for SHARPIN

mSIPL1 , protein kinase C-interacting protein RBCC like 1 , shank-associated RH domain-interacting protein , shank-interacting protein-like 1 , sharpin , hSIPL1 , SHANK-associated RH domain interacting protein , shank-interacting protein

GENE ID SPECIES
106025 Mus musculus
81858 Homo sapiens
81859 Rattus norvegicus
512499 Bos taurus
475122 Canis lupus familiaris
Fournisseurs de qualité sélectionnés pour anti-SHARPIN (SHARPIN) Anticorps
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