anti-SRY (Sex Determining Region Y)-Box 18 (SOX18) Anticorps

SOX18 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. De plus, nous expédions SOX18 Kits (23) et SOX18 Protéines (5) et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
SOX18 54345 P35713
SOX18 311723  
SOX18 20672 P43680
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Top anti-SOX18 Anticorps sur anticorps-enligne.fr

Showing 10 out of 41 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué IF, IHC, WB WB Suggested Anti-SOX18 <br /> Antibody Titration: 0.2-1 µg/mL <br /> Positive Control: Human heart 100 μL Connectez-vous pour afficher 2 to 3 Days
$289.00
Détails
Boeuf (Vache) Lapin Inconjugué WB <b>WB Suggested Anti-SOX18 Antibody Titration: </b>2.0ug/ml<br><b>Positive Control: </b>Jurkat cell lysate 100 μL Connectez-vous pour afficher 2 to 3 Days
$229.00
Détails
Boeuf (Vache) Lapin Inconjugué IHC (p), WB 50 μg Connectez-vous pour afficher 7 to 9 Days
$551.83
Détails
Cobaye Lapin Inconjugué WB 100 μg Connectez-vous pour afficher 7 to 9 Days
$493.17
Détails
Humain Lapin Inconjugué IF, WB SOX18 Antibody (N-term)  western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the SOX18 antibody detected the SOX18 protein (arrow). Fluorescent confocal image of Hela cell stained with SOX18 Antibody (N-term).Hela cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with SOX18 primary antibody (1:25, 1 h at 37℃). For secondary antibody, Alexa Fluor® 488 conjugated donkey anti-rabbit antibody (green) was used (1:400, 50 min at 37℃).Cytoplasmic actin was counterstained with Alexa Fluor® 555 (red) conjugated Phalloidin (7units/ml, 1 h at 37℃). Nuclei were counterstained with DAPI (blue) (10 µg/ml, 10 min).SOX18 immunoreactivity is localized to Nucleus significantly. 400 μL Connectez-vous pour afficher 10 to 11 Days
$324.50
Détails
Humain Lapin Inconjugué IHC (p), WB Human Testis (formalin-fixed, paraffin-embedded) stained with SOX18 antibody ABIN364480 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Uterus (formalin-fixed, paraffin-embedded) stained with SOX18 antibody ABIN364480 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Connectez-vous pour afficher 7 to 9 Days
$595.83
Détails
Humain Lapin Inconjugué ELISA, WB 100 μg Connectez-vous pour afficher 2 to 3 Days
$343.75
Détails
Humain Lapin Inconjugué IHC, ELISA, WB 50 μg Connectez-vous pour afficher 2 to 3 Days
$433.13
Détails
Boeuf (Vache) Lapin Inconjugué IHC (p), WB   50 μg Connectez-vous pour afficher 12 to 15 Days
$375.38
Détails
Boeuf (Vache) Lapin Inconjugué WB   0.1 mg Connectez-vous pour afficher 12 to 15 Days
$375.38
Détails

SOX18 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
Human , ,
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Rat (Rattus)

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Mouse (Murine)

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anti-SOX18 Anticorps mieux référencés

  1. Cow (Bovine) Polyclonal SOX18 Primary Antibody pour IF, IHC - ABIN2777725 : García-Ramírez, Martínez-González, Juan-Babot, Rodríguez, Badimon: Transcription factor SOX18 is expressed in human coronary atherosclerotic lesions and regulates DNA synthesis and vascular cell growth. dans Arteriosclerosis, thrombosis, and vascular biology 2005 (PubMed)
    Show all 4 Pubmed References

Plus d’anticorps contre SOX18 partenaires d’interaction

Human SRY (Sex Determining Region Y)-Box 18 (SOX18) interaction partners

  1. Nuclear expression of SOX18 was shown in vascular endothelial cells, basal layer cells of NS epidermis, as well as in AK, BCC and SCC (Montrer CYP11A1 Anticorps) cancer cells

  2. SOX18 plays a significant role in promoting the growth of pancreatic ductal adenocarcinoma, and might serve as a promising target for PDAC therapy

  3. Study reports SOX18 as novel risk gene for Neural tube defects (NTDs) but findings also suggest that SOX18 hypomethylation and increased expression must interplay with other environmental and (epi (Montrer TFPI Anticorps))genetic factors that are causative for NTDs.

  4. SOX18 was overexpressed in prostate cancer.SOX18 promotes prostate cancer progression via the regulation of TCF1 (Montrer HNF1A Anticorps), c-Myc (Montrer MYC Anticorps), cyclin D1 (Montrer CCND1 Anticorps) and MMP-7 (Montrer MMP7 Anticorps).

  5. the results of this study suggest that knockdown of SOX18 inhibits breast cancer cell growth and invasion, possibly by downregulating downstream oncogenic proteins, providing novel insights into the development of breast cancer therapy through targeting of SOX18.

  6. miRNAs interact with the mRNA of the SOX18 gene, but the mechanism by which they could be inhibited in cancer cells requires further examination

  7. The downregulation of SOX18 was found to significantly inhibit cell adhesion and invasion.

  8. NKD2 (Montrer NKD2 Anticorps) inhibits SOX18 and MMP-2,7,9 expression and suppresses BGC823 cell xenograft growth. NKD2 (Montrer NKD2 Anticorps) methylation may serve as a poor prognostic and chemo-sensitive marker in human gastric cancer. NKD2 (Montrer NKD2 Anticorps) impedes gastric cancer metastasis by inhibiting SOX18.

  9. GLI1 (Montrer GLI1 Anticorps) and GLI2 (Montrer GLI2 Anticorps), but not GLI3 (Montrer GLI3 Anticorps) are involved in the regulation of SOX18 gene expression in cervical carcinoma cell lines.

  10. we demonstrated that upregulation of SOX18 was associated with a poor outcome in hepatocellular carcinoma patients

Pig (Porcine) SRY (Sex Determining Region Y)-Box 18 (SOX18) interaction partners

  1. Here we demonstrate that VEGF (Montrer VEGFA Anticorps)-165 mediates MSC (Montrer MSC Anticorps) differentiation into ECs via VEGFR-2 (Montrer KDR Anticorps)-dependent induction of Sox18, which ultimately coordinates the transcriptional upregulation of specific markers of the EC phenotype

Mouse (Murine) SRY (Sex Determining Region Y)-Box 18 (SOX18) interaction partners

  1. Sox18 acts as a mesenchymal molecular switch necessary for the formation and function of the dermal papilla in all hair types.

  2. combined deletion of Sox7 (Montrer SOX7 Anticorps), Sox17 (Montrer SOX17 Anticorps), and Sox18 at the onset of retinal angiogenesis leads to a dense capillary plexus with a nearly complete loss of radial arteries and veins, whereas the presence of a single Sox17 (Montrer SOX17 Anticorps) allele largely restores arterial identity

  3. Sox18 genetically interacts with VegfC (Montrer VEGFC Anticorps) to regulate lymphangiogenesis in Zebrafish.

  4. SOX18 induction is a key step in mediating tumor lymphangiogenesis and metastasis

  5. Overexpression of wild-type SOX18 promoted capillary tube formation of HUVECs in vitro, whereas expression of dominant-negative SOX18 impaired tube formation of HUVECs and the migration of MCF-7 cells via the disruption of the actin cytoskeleton.

  6. Results indicate that Sox17 (Montrer SOX17 Anticorps) and Sox18, and possibly all three SoxF genes, are cooperatively involved in mammalian vascular development.

  7. These result can explain previously controversial data on the functional consequences of Sox18 mutations in mice and humans.

  8. Sox17 (Montrer SOX17 Anticorps)/Sox18 double-null embryos showed more severe defects in formation of anterior dorsal aorta and head/cervical microvasculature, and in some cases, aberrant differentiation of endocardial cells and defective fusion of the endocardial tube

  9. findings demonstrate a critical role for Sox18 in developmental lymphangiogenesis, and suggest new avenues to investigate for therapeutic management of human lymphangiopathies

  10. SOX18 plays role in the vascular dysfunction in hypotrichosis-lymphedema-telangiectasia syndrome.

SOX18 profil antigène

Profil protéine

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This protein plays a role in hair, blood vessel, and lymphatic vessel development. Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia.

Gene names and symbols associated with SOX18

  • SRY-box 18 (SOX18) anticorps
  • SRY box 18 (Sox18) anticorps
  • SRY (sex determining region Y)-box 18 (Sox18) anticorps
  • AI385749 anticorps
  • HLTS anticorps
  • Ra anticorps
  • Ragl anticorps

Protein level used designations for SOX18

SRY-box 18 , transcription factor SOX-18 , SRY-box containing gene 18 , Sry-related HMG-box gene 18 , ragged

GENE ID SPECIES
54345 Homo sapiens
100049667 Sus scrofa
519439 Bos taurus
311723 Rattus norvegicus
20672 Mus musculus
Fournisseurs de qualité sélectionnés pour anti-SOX18 (SOX18) Anticorps
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