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SLC12A4 encodes a member of the SLC12A transporter family. De plus, nous expédions Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 4 Protéines (6) et et beaucoup plus de produits pour cette protéine.
Showing 10 out of 48 products:
Human Polyclonal SLC12A4 Primary Antibody pour ELISA, IHC (p) - ABIN451604
Simard, Bergeron, Frenette-Cotton, Carpentier, Pelchat, Caron, Isenring: Homooligomeric and heterooligomeric associations between K+-Cl- cotransporter isoforms and between K+-Cl- and Na+-K+-Cl- cotransporters. dans The Journal of biological chemistry 2007
Human Polyclonal SLC12A4 Primary Antibody pour ELISA, IHC - ABIN238576
Wei, Akerman, Newey, Pan, Clinch, Jacob, Shen, Wilkins, Ellory: The potassium-chloride cotransporter 2 promotes cervical cancer cell migration and invasion by an ion transport-independent mechanism. dans The Journal of physiology 2011
Show all 2 Pubmed References
data indicate that Zn(2+) acting via ZnR/GPR39 (Montrer GPR39 Anticorps) has a direct role in controlling Cl(-) absorption via upregulation of basolateral KCC1 in the colon. Moreover, colonocytic ZnR/GPR39 (Montrer GPR39 Anticorps) and KCC1 reduce water loss during diarrhea and may therefore serve as effective drug targets.
The Wnk3 (Montrer WNK3 Anticorps) protein isoforms have a similar effect on SLC12 cotransporters. NKCC1 (Montrer SLC12A2 Anticorps)/2 and NCC (Montrer SLC12A3 Anticorps) were inhibited, even in hypertonicity, while KCCs were activated, even in isotonic conditions.
Insulin (Montrer INS Anticorps)-like growth factors I can induce the upregulation of KCC1 gene, and KCC1 gene participates in the invasion ability of HEC (Montrer NDC80 Anticorps)-1B cells through the ERK (Montrer EPHB2 Anticorps) signaling pathway.
KCC3 (Montrer SLC12A6 Anticorps) is the dominant isoform in erythrocytes, with variable expression of KCC1 and KCC4 (Montrer SLC12A7 Anticorps) that could result in modulation of KCC activity
the KCC1 gene promoter lacks a TATA box and is composed of an initiator element (InR (Montrer INSR Anticorps)) and a downstream promoter element (DPE)
KCC activation by IGF-1 (Montrer IGF1 Anticorps) plays an important role in IGF-1 (Montrer IGF1 Anticorps) signaling to promote growth and spread of gynecological cancers.
IGF-II (insulin-like growth factors-2) can enhance KCC1 (KC1 co-transport-1) gene expression in cervical cancer cells through signal transduction pathways
We show that a single mutant allele of Kcc1 induces widespread sickling and tissue damage, leading to premature death in a humanized mouse model of sickle cell disease
Ste20 (Montrer STK24 Anticorps)-related proline-alanine-rich kinase (SPAK (Montrer STK39 Anticorps)) and oxidative stress response 1 (OSR1 (Montrer OSR1 Anticorps)) with the cotransporters KCC3 (Montrer SLC12A6 Anticorps), NKCC1 (Montrer SLC12A2 Anticorps), and NKCC2 (Montrer SLC12A1 Anticorps) but not KCC1 and KCC4 (Montrer SLC12A7 Anticorps)
Treatment of cells expressing mouse K-Cl cotransporter Kcc1 with several chemical cross-linkers shifted Kcc1 polypeptide to higher MW forms. The N-terminal & C-terminal cytoplasmic tails of Kcc1 were not essential for Kcc1 crosslinking.
This gene encodes a member of the SLC12A transporter family. The encoded protein mediates the coupled movement of potassium and chloride ions across the plasma membrane. This gene is expressed ubiquitously. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
electroneutral potassium-chloride cotransporter 1
, erythroid K-Cl cotransporter 1
, potassium/chloride cotransporter 1
, solute carrier family 12 (potassium/chloride transporters), member 4
, solute carrier family 12 member 4
, K-Cl Co-transporter-1
, K-Cl cotransporter KCC1
, furosemide-sensitive K-Cl cotransporter
, solute carrier family 12, member 4
, K-Cl cotransporter 1
, K-Cl cotransporter 4