anti-Splicing Factor Proline/glutamine-Ric (SFPQ) Anticorps

FGF-induced protein related to a family of RNA- and DNA-binding proteins. De plus, nous expédions et et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
SFPQ 71514 Q8VIJ6
SFPQ 6421 P23246
SFPQ 252855  
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Top anti-SFPQ Anticorps sur anticorps-enligne.fr

Showing 10 out of 72 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB WB Suggested Anti-SFPQ Antibody Titration:  1.25ug/ml  ELISA Titer:  1:12500  Positive Control:  HepG2 cell lysate. SFPQ is strongly supported by BioGPS gene expression data to be expressed in HepG2 Rabbit Anti-SFPQ Antibody  Paraffin Embedded Tissue: Human Skin Cellular Data: Squamous epithelial cells Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X 100 μL Connectez-vous pour afficher 2 to 3 Days
$249.00
Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), IP, WB Western Blot: SFPQ Antibody [NBP2-20329] - Sample (30 ug of whole cell lysate) A: 293T B: A431 C: HeLa D: HepG2 7. 5% SDS PAGE gel, diluted at 1:10000. Immunohistochemistry-Paraffin: SFPQ Antibody [NBP2-20329] - Immunohistochemical analysis of paraffin-embedded Hela xenograft, using antibody at 1:500 dilution. 0.1 mL Connectez-vous pour afficher 8 to 11 Days
$516.98
Détails
Boeuf (Vache) Lapin Inconjugué IHC, WB WB Suggested Anti-SFPQ Antibody Titration:  5.0ug/ml  Positive Control:  Jurkat cell lysate SFPQ is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells Rabbit Anti-SFPQ Antibody  Paraffin Embedded Tissue: Human Muscle Cellular Data: Skeletal muscle cells Antibody Concentration: 4.0-8.0 ug/ml Magnification: 400X 100 μL Connectez-vous pour afficher 2 to 3 Days
$249.00
Détails
Humain Lapin Inconjugué ICC, IF, IHC (p), IP, IHC, WB Western Blot and Immunoprecipitation: PSF/SFPQ Antibody [ABIN253184] - Detection of Human and Mouse PSF/SFPQ by Western Blot (h&m) and Immunoprecipitation (h). Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded) and mouse NIH3T3 (M, 50 mcg) cells. Antibodies: Affinity purified rabbit anti-PSF/SFPQ antibody ABIN253184 used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. PSF/SFPQ was also immunoprecipitated by rabbit anti-PSF/SFPQ antibodies ABIN253182 and ABIN253183, which recognize upstream epitopes.  Detection: Chemiluminescence with exposure times of 3 seconds (A) and 1 Immunohistochemistry-Paraffin: SFPQ Antibody [ABIN2531845] - FFPE section of mouse renal cell carcinoma. Antibody used at a dilution of 1:250. 0.1 mL Connectez-vous pour afficher 7 to 9 Days
$559.35
Détails
Humain Lapin Inconjugué WB SFPQ Antibody (C-term) (ABIN657824) western blot analysis in NCI-H460 cell line lysates (35 µg/lane). This demonstrates the SFPQ antibody detected the SFPQ protein (arrow). All lanes : Anti-SFPQ Antibody (C-term) at 1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: NCI-H460 whole cell lysate Lane 3: HepG2 whole cell lysate Lane 4: Jurkat whole cell lysate Lane 5: A431 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 76 kDa Blocking/Dilution buffer: 5% NFDM/TBST. Dilution: 1:2000 400 μL Connectez-vous pour afficher 10 to 11 Days
$385.00
Détails
Souris Lapin Inconjugué IHC, WB Western blot analysis of extracts of various cell lines, using SFPQ antibody. 100 μL Connectez-vous pour afficher 13 to 14 Days
$393.25
Détails
Humain Souris Inconjugué IF, IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to SFPQ on formalin-fixed paraffin-embedded human thyroid nodular goiter. [antibody concentration 3 ug/ml] Immunofluorescence of monoclonal antibody to SFPQ on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Connectez-vous pour afficher 11 to 12 Days
$440.00
Détails
Roussette (Chauve-souris) Lapin Inconjugué IHC, IHC (p), WB 100 μg Connectez-vous pour afficher 11 to 14 Days
$493.17
Détails
Boeuf (Vache) Lapin Inconjugué IHC, IHC (p), WB 100 μg Connectez-vous pour afficher 11 to 14 Days
$493.17
Détails
Humain Souris Inconjugué ELISA, IF, IHC, IHC (p), WB Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-SFPQ antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg Connectez-vous pour afficher 11 to 14 Days
$550.00
Détails

anti-SFPQ Anticorps mieux référencés

  1. Human Monoclonal SFPQ Primary Antibody pour IF, IHC (p) - ABIN562836 : Melton, Jackson, Wang, Lynch: Combinatorial control of signal-induced exon repression by hnRNP L and PSF. dans Molecular and cellular biology 2007 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal SFPQ Primary Antibody pour ICC, IF - ABIN253184 : Takayama, Horie-Inoue, Katayama, Suzuki, Tsutsumi, Ikeda, Urano, Fujimura, Takagi, Takahashi, Homma, Ouchi, Aburatani, Hayashizaki, Inoue: Androgen-responsive long noncoding RNA CTBP1-AS promotes prostate cancer. dans The EMBO journal 2013 (PubMed)

  3. Human Polyclonal SFPQ Primary Antibody pour ELISA, WB - ABIN520131 : Yarosh, Tapescu, Thompson, Qiu, Mallory, Fu, Lynch: TRAP150 interacts with the RNA-binding domain of PSF and antagonizes splicing of numerous PSF-target genes in T cells. dans Nucleic acids research 2015 (PubMed)

Plus d’anticorps contre SFPQ partenaires d’interaction

Mouse (Murine) Splicing Factor Proline/glutamine-Ric (SFPQ) interaction partners

  1. SFPQ intron retention and nuclear loss are molecular hallmarks of familial and sporadic of amyotrophic lateral sclerosis.

  2. Results indicate that an splicing factor proline-glutamine rich protein (Sfpq)-dependent strategy for controlling miRNA activity takes place in cells, contributing to the complexity of miRNA-dependent gene expression control.

  3. data demonstrate that SFPQ orchestrates spatial gene expression of a newly identified RNA regulon essential for axonal viability.

  4. These results are compatible with the idea that SFPQ, plays an important role regulating proliferation and migration during the development of the cerebral cortex.

  5. these results show that PSF can repress the transcriptional activation of VEGF stimulated by IGF-1 via recruitment of the Hakai complex

  6. Quantitative proteomics reveals dynamic interaction of JNK with RNA transport granule proteins Sfpq and Nono during neuronal differentiation

  7. A protein complex was identified containing PSPC1, PSF and LMX1B, suggesting the existence of this complex in mesodiencephalic dopaminergic neurons.

  8. PSF contributes to the stability of a subset of histone genes and that loss of H2AE expression in the PSF-deficient thymocytes uniquely contributes to an increase in thymic apoptosis.

  9. analysis indicates PSF within the PER complex recruits SIN3A, a scaffold for assembly of transcriptional inhibitory complexes, and the PER complex thereby rhythmically delivers histone deacetylases to the Per1 promoter, which repress Per1 transcription

  10. Basal and cyclic AMP-induced Rbp4 transcription is regulated by a multiprotein complex that is similar to ones that modulate expression of genes of steroid hormone biosynthesis.

  11. identified as a protein kinase Calpha-binding protein in the cell nucleus

  12. PSPC1, NONO, and SFPQ form complexes with each other in Sertoli cells and may regulate androgen receptor-mediated transcriptional activity

  13. Hippocampal mRNA expression of Psf is up-regulated during contextual fear memory formation in both sexes as a specific result of the context/tone-shock association. Changes in splicing factor expression during LTM formation regulate alternative splicing.

  14. PSF binds to the proto-oncogene Rab23, repressing transcription

  15. These data from zebrafish indicate that, in vertebrates, sfpq plays a key role in neuronal development and is essential for normal brain development.

Zebrafish Splicing Factor Proline/glutamine-Ric (SFPQ) interaction partners

  1. we report the surprising finding that zebrafish respond to optic nerve lesion by inducing the expression of Sfpq and Socs3a

  2. sfpq function is required for differentiation, but not for determination, of specific classes of brain neurons.

Human Splicing Factor Proline/glutamine-Ric (SFPQ) interaction partners

  1. SFPQ dislocation was found enhanced with tau co-transfection and tau co-transfection further resulted in extended DNA disorganization in N2a cells. Overall, our results indicate that dysregulation and dislocation of SFPQ and subsequent DNA disorganization might be a novel pathway in the progression of Alzheimer's disease and frontotemporal dementia.

  2. Analytical ultracentrifugation to estimate the dimerization equilibrium of the SFPQ-containing dimers revealed that the SFPQ-containing dimers dissociate at low micromolar concentrations and that the heterodimers have higher affinities than the homodimer. Moreover, we observed that the apparent dissociation constant for the SFPQ/PSPC1 heterodimer was over 6-fold lower than that of the SFPQ/NONO heterodimer.

  3. SFPQ intron retention and nuclear loss are molecular hallmarks of familial and sporadic of amyotrophic lateral sclerosis.

  4. Vault RNAs partially induces drug resistance of human tumor cells MCF-7 by binding to the RNA/DNA-binding protein PSF and inducing oncogene GAGE6

  5. GAPLINC has a role in promoting colorectal cancer invasion via binding to PSF/NONO and partly by stimulating the expression of SNAI2

  6. PSF was found to be an important internal ribosome entry site trans acting factor (ITAF) for efficient translation of coxsackievirus B3 RNA.

  7. Mechanistic dissection reveals that NEAT1 broadly interacts with the NONO-PSF heterodimer as well as many other RNA-binding proteins and that multiple RNA segments in NEAT1, including a 'pseudo pri-miRNA' near its 3' end, help attract the Drosha-DGCR8 Microprocessor.

  8. The SFPQ*NONO complex contains an RNA binding domain, and prior work has demonstrated diverse roles in RNA metabolism. It is thus plausible that the additional repair function of NONO, revealed in cell-based assays, could involve RNA interaction.

  9. Describe the unusual morphology and expanded the morphologic spectrum of SFPQ/PSF-TFE3 renal cell carcinomas.

  10. The data suggest a model in which TRAP150 interacts with dimeric PSF to block access of RNA to RRM2, thereby regulating the activity of PSF toward a broad set of splicing events in T cells.

  11. PSF/SFPQ is a very common gene fusion partner in TFE3 rearrangement-associated perivascular epithelioid cell tumors (PEComas) and melanotic Xp11 translocation renal cancers.

  12. coiled-coil interaction motif thus provides a molecular explanation for the functional aggregation of SFPQ that directs its role in regulating many aspects of cellular nucleic acid metabolism

  13. The ability of the SFPQ/NONO complex to form varying protein assemblies, in conjunction with the effect of post-translational modifications of SFPQ modulating mRNA binding, suggests key roles affecting mRNP dynamics within the cell.

  14. MALAT1 binds to SFPQ releasing PTBP2 from the SFPQ/PTBP2 complex, the increased SFPQ-detached PTBP2 promotes cell proliferation and migration in colorectal cancer.

  15. The results of this study identify a new physiological role for the PSF-LC3B axis as a potential endogenous modulator of colon cancer treatment.

  16. NEAT1 plays an important role in the innate immune response through the transcriptional regulation of antiviral genes by the stimulus-responsive cooperative action of NEAT1 and SFPQ.

  17. Results suggest that Llme23 can function as an oncogenic RNA and directly associate the polypyrimidine tract-binding (PTB) protein-associated splicing factor (PSF)-binding lncRNA with melanoma.

  18. the effects of PSF on cell proliferation, tumor growth, and cell signaling associated with PPARgamma

  19. Partial knockdown of Annexin A2 and PSF showed decrease in p53 IRES activity and reduced levels of both the p53 isoforms.

  20. PSF and MATR3 are cellular host factors that bind viral RNA and promote Rev activity.

SFPQ profil antigène

Profil protéine

FGF-induced protein related to a family of RNA- and DNA-binding proteins

Gene names and symbols associated with SFPQ

  • splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) (Sfpq) anticorps
  • splicing factor proline/glutamine-rich (sfpq) anticorps
  • splicing factor proline and glutamine rich (SFPQ) anticorps
  • splicing factor proline and glutamine rich (Sfpq) anticorps
  • 1110004P21Rik anticorps
  • 2810416M14Rik anticorps
  • 5730453G22Rik anticorps
  • 9030402K04Rik anticorps
  • AU021830 anticorps
  • D4Ertd314e anticorps
  • Gm12940 anticorps
  • hm:zeh0027 anticorps
  • OTTMUSG00000009329 anticorps
  • POMP100 anticorps
  • PSF anticorps
  • REP1 anticorps
  • wu:fa11h12 anticorps
  • wu:fd10f03 anticorps
  • zgc:85935 anticorps

Protein level used designations for SFPQ

DNA-binding p52/p100 complex, 100 kDa subunit , PTB-associated splicing factor , PTB-associated-splicing factor , polypyrimidine tract-binding protein-associated-splicing factor , splicing factor, proline- and glutamine-rich , wis , 100 kDa DNA-pairing protein , hPOMp100 , polypyrimidine tract binding protein associated , polypyrimidine tract-binding protein-associated splicing factor , splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) , splicing factor proline/glutamine rich (polypyrimidine tract-binding protein-associated) , splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated) , NonO/p54nrb homolog , gizzard PTB-associated splicing factor

GENE ID SPECIES
71514 Mus musculus
406564 Danio rerio
6421 Homo sapiens
618226 Bos taurus
252855 Rattus norvegicus
395803 Gallus gallus
100688260 Canis lupus familiaris
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