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TAS2R16 encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily.
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genetic association studies in populations in Northern Europe, Maghreb, and Sri (Montrer SRI Anticorps) Lanka: Data suggest that SNPs in TAS2R50 (Montrer TAS2R50 Anticorps) (rs1376251), TRPM5 (Montrer TRPM5 Anticorps) (rs800345), and TAS2R16 (rs860170) are associated with cultural food preferences; TAS2R16 (rs860170) strongly differentiates populations and is associated to salicin bitterness perception. (TRPM5 (Montrer TRPM5 Anticorps) = transient receptor potential cation channel subfamily M member 5 (Montrer TRPM5 Anticorps))
Bitter taste receptor (Montrer TAS2R7 Anticorps) polymorphisms in TAS2R16 may be associated with human aging
The authors discuss the association between the TAS2R16 gene and the evolution of bitter taste receptors in different populations.
TAS2R16 is responsible for the bitterness of gentiobiose.
TAS2R16 is present in taste receptor cells on the tongue and is activated by bitter beta-glucopyranosides, and mediates bitter taste
Functional variant in a bitter-taste receptor (Montrer TAS2R7 Anticorps) (hTAS2R16) influences risk of alcohol dependence, especially in African-Americans.
Functional variants in both TAS2R16 and TAS2R38 (Montrer TAS2R38 Anticorps) correlate with alcohol consumption in African-American families.
This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily. These family members are specifically expressed by taste receptor cells of the tongue and palate epithelia. Each of these apparently intronless genes encodes a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes in chromosome 7 and is genetically linked to loci that influence bitter perception.
taste receptor type 2 member 16
, taste receptor T2R16
, bitter taste receptor Bota-T2R16
, candidate taste receptor mt2r40
, taste receptor, type 2, member 16
, candidate taste receptor T2R16