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USP8 Protéines

Hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation.

5 Résultats:

Ubiquitin Specific Peptidase 8 (USP8) (AA 1-1118) protein (His tag) Protein

USP8 Origine: Humain Source: Cellules d'insectes Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
N° du produit ABIN3096238
$13,376.85
Plus frais de port $45.00 et $22.00 pour carboglace
1 mg (More quantities available)
local_shipping Destination: Etats-Unis
Envoi sous 70 jours ouvrables

Ubiquitin Specific Peptidase 8 (USP8) (AA 777-1118) protein (T7 tag,His tag) Protein

USP8 Origine: Humain Source: Escherichia coli (E. coli) Recombinant ≥ 92 % ELISA, IP, SDS, WB
N° du produit ABIN6237081
$410.00
Plus shipping costs $45.00
50 μg (More quantities available)
local_shipping Destination: Etats-Unis
Envoi sous 15 à 18 jours ouvrables

Ubiquitin Specific Peptidase 8 (USP8) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag) Protein

USP8 Origine: Humain Source: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD
N° du produit ABIN2734893
$888.80
Plus frais de port $45.00 et $22.00 pour carboglace
20 μg
local_shipping Destination: Etats-Unis
Envoi sous 11 jours ouvrables

Ubiquitin Specific Peptidase 8 (USP8) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag) Protein

USP8 Origine: Humain Source: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD
N° du produit ABIN2735146
$888.80
Plus frais de port $45.00 et $22.00 pour carboglace
20 μg
local_shipping Destination: Etats-Unis
Envoi sous 11 jours ouvrables

Ubiquitin Specific Peptidase 8 (USP8) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag) Protein

USP8 Origine: Humain Source: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD
N° du produit ABIN2735145
$932.80
Plus frais de port $45.00 et $22.00 pour carboglace
20 μg
local_shipping Destination: Etats-Unis
Envoi sous 11 jours ouvrables
  • Type Protein
    • Protein
  • Target Ubiquitin Specific Peptidase 8 (USP8)
    • Ubiquitin Specific Peptidase 8 (USP8)
    • Hemagglutinin (HA)
    • Ribosome Binding Factor A (RBFA)
    • Tumor Necrosis Factor alpha (TNF)
    • S-Adenosyl-Methionine Synthase (METK)
    • Interleukin 6 (IL6)
    • Interferon gamma (IFNG)
    • Hemoglobin beta (HBB)
    • Triosephosphate Isomerase 1 (TPI1)
    • Interleukin 4 (IL4)
    • Interleukin 1, beta (IL1B)
    • Thymidylate Kinase (Tmk)
    • Interleukin 2 (IL2)
    • Uracil-DNA Glycosylase (UNG)
    • Fibroblast Growth Factor 2 (Basic) (FGF2)
    • Growth Hormone 1 (GH1)
    • Lipoyl synthase lipA
    • Interleukin 10 (IL10)
    • KIT Ligand (KITLG)
    • Malate Dehydrogenase (MDH)
    • Leptin (LEP)
    • Epidermal Growth Factor (EGF)
    • Insulin-Like Growth Factor 1 (IGF1)
    • Interleukin 8 (IL8)
    • Vascular Endothelial Growth Factor A (VEGFA)
    • Interleukin 3 (IL-3)
    • Myoglobin (MB)
    • Queuine tRNA-Ribosyltransferase 1 (QTRT1)
    • serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1)
    • Hemoglobin, alpha 1 (HBA1)
    • Interleukin 1 alpha (IL1A)
    • phosphatidylserine Decarboxylase (PISD)
    • Prolactin (PRL)
    • Albumin (ALB)
    • Interleukin 13 (IL13)
    • Streptavidin
    • CD40 Ligand (CD40LG)
    • Interleukin 15 (IL15)
    • beta-2-Microglobulin (B2M)
    • Chemokine (C-X-C Motif) Ligand 12 (CXCL12)
    • Aspartate Carbamoyltransferase (PYRB)
    • Phosphoglucosamine Mutase (GLMM)
    • Porphobilinogen Deaminase (HEMC)
    • Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA)
    • Chemokine (C-C Motif) Ligand 2 (CCL2)
    • Adiponectin (ADIPOQ)
    • Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2)
    • Gp120
    • Fibroblast Growth Factor 1 (Acidic) (FGF1)
    • Interleukin 33 (IL33)
    • Transforming Growth Factor, beta 1 (TGFB1)
  • Application
    • Antibody Production (AbP)
    • Functional Studies (Func)
    • Protein Interaction (PI)
    • Standard (STD)
    • ELISA
    • SDS-PAGE (SDS)
    • Western Blotting (WB)
    • Immunoprecipitation (IP)
    • Crystallization (Crys)
  • Réactivité
    • Humain
  • Images disponible
  • Hote
    • HEK-293 Cells
    • Escherichia coli (E. coli)
    • Cellules d'insectes
  • Epitope
    • AA 1-1118
    • AA 777-1118
    • Transcript Variant 1
    • Transcript Variant 2
    • Transcript Variant 3
  • Conjugué
    • Inconjugué
    • Myc-DYKDDDDK Tag
    • His tag
    • T7 tag,His tag
  • Type Proteine
    • Recombinant
  • Format
    • Liquid

Profil protéine USP8

Profil protéine

Hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation. Converts both 'Lys-48' an 'Lys-63'-linked ubiquitin chains. Catalytic activity is enhanced in the M phase. Involved in cell proliferation. Required to enter into S phase in response to serum stimulation. May regulate T-cell anergy mediated by RNF128 via the formation of a complex containing RNF128 and OTUB1. Probably regulates the stability of STAM2 and RASGRF1. Regulates endosomal ubiquitin dynamics, cargo sorting, membrane traffic at early endosomes, and maintenance of ESCRT-0 stability. The level of protein ubiquitination on endosomes is essential for maintaining the morphology of the organelle. Deubiquitinates EPS15 and controles tyrosine kinase stability. Removes conjugated ubiquitin from EGFR thus regulating EGFR degradation and downstream MAPK signaling. Involved in acrosome biogenesis through interaction with the spermatid ESCRT-0 complex and microtubules. Deubiquitinates BIRC6/bruce and KIF23/MKLP1.

Gene names and symbols associated with USP8

  • ubiquitin carboxyl-terminal hydrolase 8 (LOC9310109) anticorps
  • ubiquitin carboxyl-terminal hydrolase 8 (MGYG_00369) anticorps
  • ubiquitin specific peptidase 8 (USP8) anticorps
  • ubiquitin specific peptidase 8 (Usp8) anticorps
  • AI574262 anticorps
  • AW557536 anticorps
  • HumORF8 anticorps
  • mKIAA0055 anticorps
  • Ubpy anticorps

Protein level used designations for USP8

ubiquitin carboxyl-terminal hydrolase 8 , ubiquitin-specific-processing protease 8 , ubiquitin specific peptidase 8 , ubiquitin carboxyl-terminal hydrolase 8-like , deubiquitinating enzyme 8 , hUBPy , ubiquitin isopeptidase Y , ubiquitin specific protease 8 , ubiquitin thioesterase 8 , ubiquitin thiolesterase 8 , putative deubiquitinating enzyme

GENE ID SPECIES
9310109 Arabidopsis lyrata subsp. lyrata
10031598 Arthroderma gypseum CBS 118893
100408559 Callithrix jacchus
100437819 Pongo abelii
9101 Homo sapiens
296121 Rattus norvegicus
84092 Mus musculus
100157546 Sus scrofa
415451 Gallus gallus
100351436 Oryctolagus cuniculus
100720255 Cavia porcellus
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