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The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. De plus, nous expédions UBE2H Protéines (18) et beaucoup plus de produits pour cette protéine.
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Tal1 expression activated UBE2H expression, whereas Tal1 knock-down reduced UBE2H expression and ubiquitin transfer activity.
Results suggest that the UBE2H gene is not implicated in sporadic ALS.
UBE2H gene could be one of the 7q-susceptibility loci for autistic disorder.
MG53 (Montrer TRIM72 Anticorps) is an ubiquitin E3 ligase that induces IRS-1 (Montrer IRS1 Anticorps) ubiquitination with the help of an E2-conjugating enzyme, UBE2H.
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein sequence is 100% identical to the mouse homolog and 98% identical to the frog and zebrafish homologs. Three alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.
ubiquitin-conjugating enzyme E2 H
, ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)
, Ubiquitin-conjugating enzyme E2 H
, ubiquitin-conjugating enzyme E2H
, ubiquitin-conjugating enzyme E2H (UBC8 homolog)
, ubiquitin-conjugating enzyme E2-21 KD
, GID complex subunit 3, UBC8 homolog
, ubiquitin carrier protein H
, ubiquitin-conjugating enzyme E2-20K
, ubiquitin-conjugating enzyme E2H (homologous to yeast UBC8)
, ubiquitin-protein ligase H