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The protein encoded by UBE2K belongs to the ubiquitin-conjugating enzyme family. De plus, nous expédions Ubiquitin-Conjugating Enzyme E2K Protéines (17) et Ubiquitin-Conjugating Enzyme E2K Kits (3) et beaucoup plus de produits pour cette protéine.
Showing 10 out of 113 products:
Human Polyclonal UBE2K Primary Antibody pour WB - ABIN1881965
Bae, Kho, Lee, Rhim, Kang: Hip2 interacts with and destabilizes Smac/DIABLO. dans Biochemical and biophysical research communications 2010
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Human Polyclonal UBE2K Primary Antibody pour IF, WB - ABIN1882088
Furukawa, Kubo, Kikuchi, Tokura, Fujita, Sakurabayashi: Regulation of macrophage-specific gene expression by degenerated lipoproteins. dans Electrophoresis 2000
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Cow (Bovine) Polyclonal UBE2K Primary Antibody pour WB - ABIN2787510
Christensen, Brzovic, Klevit: E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages. dans Nature structural & molecular biology 2007
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Human Polyclonal UBE2K Primary Antibody pour IHC (p), IHC - ABIN268582
Kalchman, Graham, Xia, Koide, Hodgson, Graham, Goldberg, Gietz, Pickart, Hayden: Huntingtin is ubiquitinated and interacts with a specific ubiquitin-conjugating enzyme. dans The Journal of biological chemistry 1996
The crystal structure of a Ube2K~ubiquitin conjugate has been described, and it was shown that even though it is monomeric, Ube2K can synthesize Lys48-linked ubiquitin chains.
Hip2, a ubiquitin-conjugating enzyme (Montrer Ube2t Anticorps), can overcome radiation-induced G2/M cell cycle arrest and trigger the entry into mitosis.
An extract of bark from the tropical rainforest plant Byrsonima crassifolia was screened for inhibition of diubiquitin (Montrer UBD Anticorps) formation by the human ubiquitin-conjugating enzyme E2-25K.
one of the roles of the C-terminal UBA domain, in the context of E2-25K, is to increase processivity in Lys48-linked polyubiquitin (Montrer UBB Anticorps) chain synthesis, possibly through increased binding to the ubiquitinated substrate.
Results suggest that the interaction between E2-25K and UBB (Montrer UBB Anticorps)(+1) is critical for the synthesis and accumulation of UBB (Montrer UBB Anticorps)(+1)-anchored polyubiquitin (Montrer UBB Anticorps), which results in proteasomal inhibition and neuronal cell death.
This study suggests that Hip2 might be involved in the regulation of Smac (Montrer DIABLO Anticorps)-mediated apoptosis.
Results suggest that in permeabilized, US11-expressing cells polyubiquitination of the MHC class I heavy chain substrate can be catalyzed by E2-25K.
E2-25K is involved in aggregate formation of expanded polyglutamine proteins and polyglutamine-induced cell death.
E2-25K has a crucial role in oxidative stress and cerebral Ischemia/Reperfusion-induced damage through inhibiting proteasome via its SUMOylation.
E2-25K/Hip-2 is thus an essential upstream regulator of the expression and activation of caspase-12 (Montrer CASP12 Anticorps) in endoplasmic reticulum stress-mediated Abeta (Montrer APP Anticorps) neurotoxicity.
The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene.
ubiquitin-conjugating enzyme E2K (UBC1 homolog)
, huntingtin interacting protein 2
, ubiquitin-conjugating enzyme E2-25K
, ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)
, ubiquitin-conjugating enzyme E2 K
, ubiquitin-conjugating enzyme E2-25 kDa
, huntingtin-interacting protein 2
, ubiquitin carrier protein
, ubiquitin-conjugating enzyme E2(25K)
, ubiquitin-conjugating enzyme E2-25 KDA
, ubiquitin-protein ligase