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IL-6 anticorps (HRP)

IL6 Reactivité: Humain WB, ELISA, IHC, Neut, RIA Hôte: Lapin Polyclonal HRP
N° du produit ABIN1043799
  • Antigène Voir toutes IL-6 (IL6) Anticorps
    IL-6 (IL6) (Interleukin 6 (IL6))
    Reactivité
    • 181
    • 135
    • 73
    • 28
    • 22
    • 21
    • 15
    • 13
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    Humain
    Hôte
    • 194
    • 84
    • 72
    • 13
    • 4
    • 3
    • 2
    Lapin
    Clonalité
    • 214
    • 155
    • 1
    Polyclonal
    Conjugué
    • 200
    • 63
    • 27
    • 12
    • 11
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IL-6 est conjugé à/à la HRP
    Application
    • 266
    • 138
    • 104
    • 62
    • 52
    • 49
    • 41
    • 41
    • 38
    • 31
    • 25
    • 25
    • 22
    • 20
    • 15
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Neutralization (Neut), Radioimmunoassay (RIA)
    Specificité
    This purified antibody has been heated to 56°C for 30 minutes. In ELISA and other immunoreactive assays, this antibody will recognize both native and recombinant human Il-6 in cell supernatants and certain body fluids. In Western blot analysis of natural cell products or human body fluids, multiple bands of IL-6 will appear due to the variable amount of glycosylation on the molecule.  A control of similarly diluted normal rabbit IgG is recommended. This product has minimal reactivity with mouse IL-6.
    Attributs du produit
    This purified antibody has been tested for use in ELISA and western blotting. Reactivity is also expected in neutralizations, radioimmunoassay and immunohistochemistry. The endotoxin content is estimated to be < 10 pg/µL by the LAL method. By western blot a band approximately 23.7 kDa in size corresponding to native human IL-6 protein is expected in the appropriate cell lysate or extract. Specific conditions for reactivity should be optimized by the end user.
    Purification
    purified
    Immunogène
    This purified antibody was prepared from whole rabbit serum produced by repeated immunizations with full length recombinant human IL-6 produced in E.coli.
    Immunogen Type: RecombinantProtein
    Isotype
    IgG
    Top Product
    Discover our top product IL6 Anticorps primaire
  • Indications d'application
    This purified antibody has been tested for use in ELISA and western blotting. Reactivity is also expected in neutralizations, radioimmunoassay and immunohistochemistry. The endotoxin content is estimated to be < 10 pg/µL by the LAL method. By western blot a band approximately 23.7 kDa in size corresponding to native human IL-6 protein is expected in the appropriate cell lysate or extract. Specific conditions for reactivity should be optimized by the end user.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitution Buffer: Restore with deionized water (or equivalent), Reconstitution Volume: 100 µL
    Concentration
    1.1 mg/ml
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free
    Agent conservateur
    Gentamicin sulfate
    Conseil sur la manipulation
    Do NOT add Sodium Azide!
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
    Date de péremption
    12 months
  • Novick: "Current concepts in the management of renovascular hypertension and ischemic renal failure." dans: American journal of kidney diseases : the official journal of the National Kidney Foundation, Vol. 13, Issue 6 Suppl 1, pp. 33-7, (1989) (PubMed).

  • Antigène
    IL-6 (IL6) (Interleukin 6 (IL6))
    Autre désignation
    IL-6 (IL6 Produits)
    Synonymes
    anticorps BSF2, anticorps HGF, anticorps HSF, anticorps IFNB2, anticorps IL-6, anticorps Il-6, anticorps ILg6, anticorps Ifnb2, anticorps il6, anticorps CHIL-6, anticorps interleukin 6, anticorps interleukin-6, anticorps IL6, anticorps Il6, anticorps il-6, anticorps IL-6
    Sujet
    IL-6 is a secreted cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response and plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. IL-6 induces myeloma and plasmacytoma growth and induces nerve cells differentiation and acts on B-cells, T-cells, hepatocytes, hematopoeitic progenitor cells and cells of the CNS. IL-6 also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance.
    Synonyms: HSF, Hybridoma growth factor, Hybridoma plasmacytoma growth factor, IFNB2, IL 6, IL6 protein, Interferon beta 2, Interleukin 6, BSF2, CDF
    ID gène
    3569
    NCBI Accession
    NP_000591
    UniProt
    P05231
    Pathways
    Signalisation TLR, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
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