ATG14 anticorps

N° du produit ABIN1077377

Détail du produit anti-ATG14 anticorps

Antigène: ATG14 (ATG14 Autophagy Related 14 (ATG14))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATG14 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Specificité: At least three isoforms of ATG14 are known to exist, this antibody will detect all three isoforms

Purification: Affinity chromatography purified via peptide column

Immunogène: ATG14 antibody was raised against an 18 amino acid synthetic peptide near the center of human ATG14.

Isotype: IgG

Information d'application

Indications d'application: ATG14 antibody can be used for detection of ATG14 by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.

Commentaires:

(IN) Autophagy-related 14

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: 4 °C

Stockage commentaire: ATG14 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Date de péremption: 12 months

Détails sur ATG14

Antigène: ATG14 (ATG14 Autophagy Related 14 (ATG14))

Autre désignation: ATG14 (ATG14 Produits)

Synonymes: anticorps ATG14L, anticorps BARKOR, anticorps KIAA0831, anticorps 4832427M01, anticorps Atg14L, anticorps D14Ertd114e, anticorps D14Ertd436e, anticorps RGD1304610, anticorps autophagy related 14, anticorps ATG14, anticorps Atg14

Sujet: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein ATG1. ATG14 is a subunit of a class III phosphatidylinositol (PtdIns) 3-kinase complex that targets the complex to the endoplasmic reticulum, the site of autophagosome formation.
Synonyms: Autophagy-related 14, ATG14L, beclin1-associated autophagy-related key regulator, beclin 1-interacting protein, BARKOR

Poids moléculaire: 54 kDa

ID gène: 22863

NCBI Accession: NP_055739

Pathways: Autophagy