SCN5A anticorps (AA 1021-1034)

N° du produit ABIN1104138

Détail du produit anti-SCN5A anticorps

Antigène: SCN5A (Sodium Channel, Voltage-Gated, Type V, alpha Subunit (SCN5A))

Épitope: AA 1021-1034

Reactivité: Humain, Singe

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp SCN5A est non-conjugé

Application: ELISA

Specificité: Human SCN5A / Nav1.5. This antibody is expected to recognize all reported isoforms (NP_932173.1, NP_000326.2, NP_001092874.1, NP_001092875.1, NP_001153632.1, NP_001153633.1).

Homologie: Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey (100%) Marmoset (86%).

Purification: Immunoaffinity purified

Immunogène: Synthetic peptide C-PTRKETRFEEGEQP from an internal region of human SCN5A / Nav1.5 (NP_932173.1, NP_000326.2, NP_001092874.1, NP_001092875.1, NP_001153632.1, NP_001153633.1). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey (100%), Marmoset (86%).

Type of Immunogen: Synthetic peptide

Information d'application

Indications d'application: Approved: Peptide-ELISA (1:16000)

Usage: Peptide ELISA: antibody detection limit dilution 1:16000. Western blot: Preliminary experiments gave an approx 80kD band in HeLa lysates after 0.3 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 227kD according to NP_932173.1. The 80kD band was successfully blocked by incubation with the immunizing peptide.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Minimize freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur SCN5A

Antigène: SCN5A (Sodium Channel, Voltage-Gated, Type V, alpha Subunit (SCN5A))

Autre désignation: SCN5A / Nav1.5 (SCN5A Produits)

Synonymes: anticorps Nav1.5, anticorps Nav1.5c, anticorps SkM1, anticorps SkM2, anticorps mH1, anticorps CDCD2, anticorps CMD1E, anticorps CMPD2, anticorps HB1, anticorps HB2, anticorps HBBD, anticorps HH1, anticorps ICCD, anticorps IVF, anticorps LQT3, anticorps PFHB1, anticorps SSS1, anticorps VF1, anticorps SCAL, anticorps sodium voltage-gated channel alpha subunit 5, anticorps sodium channel, voltage-gated, type V, alpha, anticorps SCN5A, anticorps Scn5a

Sujet: Name/Gene ID: SCN5A
Subfamily: Sodium channel - voltage-gated
Family: Ion Channel

Synonyms: SCN5A, CDCD2, CMPD2, HB1, HB2, HH1, HBBD, Nav1.5, IVF, RSKM2X, SCAL, Scn2x, LQT3, SSS1, MH1, VF1, PFHB1, RATRSKM2X, SkM2, CMD1E, ICCD, RH1, RSkM2

ID gène: 6331

NCBI Accession: NP_932173, NP_000326, NP_001092874, NP_001092875, NP_001153632, NP_001153633

UniProt: Q14524