ADRA2A anticorps (C-Term)

N° du produit ABIN1105320

Détail du produit anti-ADRA2A anticorps

Antigène: ADRA2A (Alpha-2A Adrenergic Receptor (ADRA2A))

Épitope: C-Term

Reactivité: Humain, Rat, Souris, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADRA2A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects Alpha-2A adrenergic receptor near C-term. No cross reactivity with other proteins.

Réactivité croisée (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human, Rat.

Purification: Immunogen affinity purified

Immunogène: Synthetic peptide corresponding to a sequence mapping near the C-terminal of human ADRA2 .Remarks: Sequence is identical to the related rat and mouse sequence.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 0.2 mL of distilled water to yield a concentration of 0.5 mg/mL.

Buffer: 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium Azide

Agent conservateur: Sodium azide, Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur ADRA2A

Antigène: ADRA2A (Alpha-2A Adrenergic Receptor (ADRA2A))

Autre désignation: alpha-2A Adrenergic Receptor (ADRA2A Produits)

Synonymes: anticorps ADRA2A, anticorps AW122659, anticorps Adra-2, anticorps Adra-2a, anticorps alpha(2A)AR, anticorps alpha2-C10, anticorps alpha2A, anticorps alpha2A-AR, anticorps ADRA2, anticorps ADRA2R, anticorps ADRAR, anticorps ALPHA2AAR, anticorps ZNF32, anticorps CA2-47, anticorps RATRG20, anticorps RG20, anticorps PORA2AR, anticorps adrenoceptor alpha 2A, anticorps alpha-2A adrenergic receptor-like, anticorps adrenergic receptor, alpha 2a, anticorps adra2a, anticorps ADRA2A, anticorps LOC100414445, anticorps Adra2a

Sujet: Alpha-2-adrenergic receptor (ADRA2), also known as platelet type adrenoceptor alpha-2A ,is a member of G protein-coupled receptor superfamily. This gene, which can identify a DraI RFLP of the ADRAR gene, mapped to 10q23-q25, is found in the distal region of mouse chromosome 19 and abundantly expressed in giant cell. ADRA2 acts a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. It has 3 highly homologous subtypes: ADRA2A, ADRA2B and ADRA2C. Studies in mouse suggested that both the ADRA2A and ADRA2C subtypes are required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. ADRA2A receptors inhibited transmitter release at high stimulation frequencies, whereas the ADRA2C subtype modulated neurotransmission at lower levels of nerve activity.Synonyms: ADRA2A, ADRA2R, ADRAR, Alpha-2A adrenoceptor, Alpha-2A adrenoreceptor

ID gène: 150

NCBI Accession: NP_000672

UniProt: P08913

Pathways: EGFR Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Negative Regulation of Transporter Activity