DREAM anticorps (N-Term)

N° du produit ABIN1105647

Détail du produit anti-DREAM anticorps

Antigène: DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))

Épitope: N-Term

Reactivité: Humain, Chien, Boeuf (Vache)

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp DREAM est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Séquence: SLLGDLGHTP LS-C

Specificité: This antibody is expected to recognize Isoform 1 of KCNIP3 (NP_038462.1) only.

Réactivité croisée (Details): Species reactivity (expected):Canine (Dog), Bovine.
Species reactivity (tested):Human.

Purification: Purification: Affinity Chromatography

Immunogène: Synthetic peptide with sequence from the N-terminus of Human KCNIP3 (NP_038462.1). Genename: KCNIP3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur DREAM

Antigène: DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))

Autre désignation: Calsenilin (KCNIP3 Produits)

Synonymes: anticorps CSEN, anticorps DREAM, anticorps KCHIP3, anticorps 4933407H12Rik, anticorps AI413860, anticorps Csen, anticorps KChIP3, anticorps R74849, anticorps Dream, anticorps rKChIP3, anticorps csen, anticorps im:7145308, anticorps kcnip3, anticorps zgc:73306, anticorps KCNIP3, anticorps potassium voltage-gated channel interacting protein 3, anticorps Kv channel-interacting protein 4, anticorps calsenilin, anticorps Kv channel interacting protein 3, calsenilin, anticorps Kv channel interacting protein 3b, calsenilin, anticorps KCNIP3, anticorps LOC5568664, anticorps CpipJ_CPIJ002549, anticorps Tsp_05009, anticorps Kcnip3, anticorps kcnip3b, anticorps kcnip3

Sujet: KChIP3 is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This protein is also shown to function as a calcium-regulated transcriptional repressor, and to interact with presenilins. Mutations in the presenilin genes have been implicated in Alzheimer's disease. Due to utilization of an alternate in-frame translation start codon, the gene for this protein encodes two isoforms with different sizes.Synonyms: A-type potassium channel modulatory protein 3, CSEN, DRE-antagonist modulator, DREAM, KCHIP3, KCNIP3, Kv channel-interacting protein 3

Poids moléculaire: 29.2 kDa according to NP_038462.1.

ID gène: 30818

NCBI Accession: NP_001030086