CD21 anticorps
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- Antigène Voir toutes CD21 (CR2) Anticorps
- CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD21 est non-conjugé
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Application
- Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Réactivité croisée (Details)
- Species reactivity (tested):Human.
- Purification
- Ig Fraction
- Immunogène
- A BALB/c mouse was immunized subcutaneously in its footpads with fragments of a Human tonsil. After fusing the lymphocytes from the popliteal lymph nodes of this mouse with murine SP2/0 myeloma cells
- Clone
- 4C5
- Isotype
- IgG2a
- Top Product
- Discover our top product CR2 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 60 μg Ig/ml
- Buffer
- 0.09 % Sodium Azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for Three months or (in aliquots) at -20 °C for longer.
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- Antigène
- CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))
- Autre désignation
- CD21 (CR2 Produits)
- Synonymes
- anticorps C3DR, anticorps CD21, anticorps CR, anticorps CVID7, anticorps SLEB9, anticorps Cd21, anticorps cd21, anticorps CR1, anticorps CR1-L, anticorps CR2, anticorps complement C3d receptor 2, anticorps complement C3b/C4b receptor 1 (Knops blood group), anticorps CR2, anticorps Cr2, anticorps CR1
- Sujet
- CD21 is a type I integral membrane glycoprotein that serves as a receptor for the C3d complement fragment and for the Epstein-Barr virus. It plays a role in B cell activation and proliferation and undergoes phosphorylation after B cell activation with phorbol esters. CD21 is expressed on mature B cells, follicular Dendritic cells, pharyngeal and cervical epithelial cells and a subset of thymocytes. The adaptive immune response is tightly regulated to limit responding cells in an antigen-specific manner. On B cells, co-receptors CD21/CD19 modulate the strength of B cell Ag receptor (BCR) signals, thereby influencing cell fate. Complement receptor (CR) type 2 (CR2/ CD21) is normally expressed during the immature and mature stages of B cell development. In association with CD19, CR21 plays an important role in enhancing mature B cell responses to foreign antigen.Synonyms: C3DR, C3d receptor, CR2, Complement C3d receptor, Complement receptor type 2, Dendritic Cell Marker, EBV Receptor, Epstein-Barr virus receptor
- Poids moléculaire
- 145 kDa
- ID gène
- 9606
- UniProt
- P20023
- Pathways
- Système du Complément
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