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FGFR2 anticorps (C-Term)
FGFR2
Reactivité: Humain, Souris, Rat
WB, IHC (p)
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN1106281
Détail du produit anti-FGFR2 anticorps
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Antigène
Voir toutes FGFR2 Anticorps
FGFR2
(Fibroblast Growth Factor Receptor 2 (FGFR2))
Épitope
Tous les épitopes à travers FGFR2 Anticorps.
C-Term
Reactivité
Toutes les réactivités sur FGFR2 Anticorps
Humain, Souris, Rat
Hôte
Toutes les hôtes sur FGFR2 Anticorps
Lapin
Clonalité
Toutes les clonalités sur FGFR2 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers FGFR2 Anticorps
Cet anticorp FGFR2 est non-conjugé
Application
Tous les applications à travers FGFR2 Anticorps.
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificité
Recognizes CD332 / FGFR-2. No cross reactivity with other proteins.
Réactivité croisée (Details)
Species reactivity (expected):Rat. Species reactivity (tested):Human, Mouse.
Purification
Immunoaffinity Chromatography
Immunogène
A synthetic peptide corresponding to a sequence at the C-terminal of Human FGFR2, identical to the related Rat and Mouse sequence.
Isotype
IgG
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Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Reconstitution
Restore with 0.2 mL of distilled water to yield a concentration of 0.5 mg/mL.
Concentration
0.5 mg/mL
Buffer
5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal and 0.05 mg Sodium Azide
Agent conservateur
Sodium azide, Thimerosal (Merthiolate)
Précaution d'utilisation
This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody after reconstitution at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Détails sur FGFR2
(cache)
Antigène
FGFR2
(Fibroblast Growth Factor Receptor 2 (FGFR2))
Autre désignation
CD332 / FGFR-2 (FGFR2 Produits )
Synonymes
anticorps FGFR2, anticorps FGFR2IIIb, anticorps bek, anticorps bfr-1, anticorps cd332, anticorps cek3, anticorps cfd1, anticorps ect1, anticorps fgfr-2, anticorps jws, anticorps k-sam, anticorps kgfr, anticorps tk14, anticorps tk25, anticorps xfgfr2, anticorps DKFZp469H1521, anticorps BBDS, anticorps BEK, anticorps BFR-1, anticorps CD332, anticorps CEK3, anticorps CFD1, anticorps ECT1, anticorps JWS, anticorps K-SAM, anticorps KGFR, anticorps TK14, anticorps TK25, anticorps AU043015, anticorps AW556123, anticorps Bek, anticorps Fgfr-2, anticorps Fgfr-7, anticorps Fgfr7, anticorps KGFRTr, anticorps svs, anticorps FGF-R, anticorps fgfr72IIIb, anticorps FGFR, anticorps fc56c05, anticorps wu:fc56c05, anticorps fibroblast growth factor receptor 2, anticorps fibroblast growth factor receptor 2 L homeolog, anticorps FGFR2, anticorps LOC100084641, anticorps fgfr2, anticorps Fgfr2, anticorps fgfr2.L
Sujet
Fibroblast growth factor receptor 2 (FGFR2) is a receptor for fibroblast growth factor encoded on a gene residing on chromosome 10. FGFR2 has also been designated as CD332. FGFR2 is a membrane-spanning tyrosine kinase that serves as a high affinity receptor for several members of the fibroblast growth factor (FGF) family. Its signals are absolutely required for vertebrate limb induction and that an FGFR2 signal is essential for the reciprocal regulation loop between FGF8 and FGF10 during limb induction. (1) FGFR2 contributes to the outgrowth, differentiation, and maintenance of the inner cell mass and raise the possibility that this activity is mediated by FGF4 signals transmitted by FGFR2. The role of early FGF signaling in pregastrulation development as a possible adaptation to mammalian (amniote) embryogenesis is discussed. (2)Synonyms: BEK, FGFR2, Fibroblast growth factor receptor 2, KGFR, KSAM, Keratinocyte growth factor receptor 2
ID gène
2263
NCBI Accession
NP_000132
UniProt
P21802
Pathways
Signalisation RTK , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Regulation of Muscle Cell Differentiation , Skeletal Muscle Fiber Development , Growth Factor Binding
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