LGR5 anticorps

N° du produit ABIN1112906

Détail du produit anti-LGR5 anticorps

Antigène: LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LGR5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Purification: affinity purified

Isotype: IgG

Information d'application

Indications d'application: WB (1:1000-2000), IHC-P (1:200), ICC (1:50). Other applications have not been tested. The optimal dilutions should be determined by end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: TBS (pH7.4), 0.5% BSA, 40% Glycerol and 0.05% Sodium Azide.

Agent conservateur: Sodium azide, Thimerosal (Merthiolate)

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C after thawing (1 week). Aliquot and store at -20 °C for long term (at least one year). Avoid repeated freeze and thaw cycles.

Date de péremption: 12 months

Détails sur LGR5

Antigène: LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))

Autre désignation: Leucine-rich repeat-containing G-protein coupled receptor 5, LGR5 (LGR5 Produits)

Synonymes: anticorps lgr5-a, anticorps lgr5a, anticorps FEX, anticorps Gpr49, anticorps GPR49, anticorps GPR67, anticorps GRP49, anticorps HG38, anticorps leucine-rich repeat containing G protein-coupled receptor 5 L homeolog, anticorps leucine rich repeat containing G protein coupled receptor 5, anticorps leucine rich repeat containing G protein-coupled receptor 5, anticorps lgr5.L, anticorps Lgr5, anticorps LGR5

Sujet: Leucine-rich repeat-containing G-protein coupled receptor 5(LGR5), also known as GPR49, is a 907-amino acid 7-transmembrane protein, belongs to G Protein-Coupled Receptor. The differential expression of GPR49 between normal and tumor tissue was significant. GPR49 was upregulated in colon primary tumor tissues. In addition to colon tumors, GPR49 was also found to be upregulated in ovarian primary tumor tissues. Moreover, the expression level of GPR49 in colon and ovarian tumors increased in more advanced tumors suggesting a role for the receptor in tumor progression.

Pathways: Signalisation WNT