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TNFRSF10B anticorps (Biotin)
TNFRSF10B
Reactivité: Humain
FACS, IHC, IP, ICC, Func
Hôte: Souris
Monoclonal
HS201
Biotin
N° du produit ABIN1169242
Détail du produit anti-TNFRSF10B anticorps (Biotin)
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Antigène
Voir toutes TNFRSF10B Anticorps
TNFRSF10B
(Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
Reactivité
Toutes les réactivités sur TNFRSF10B Anticorps
Humain
Hôte
Toutes les hôtes sur TNFRSF10B Anticorps
Souris
Clonalité
Toutes les clonalités sur TNFRSF10B Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers TNFRSF10B Anticorps
Cet anticorp TNFRSF10B est conjugé à/à la Biotin
Application
Tous les applications à travers TNFRSF10B Anticorps.
Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC), Functional Studies (Func)
Specificité
Recognizes human TRAIL-R2.
Réactivité croisée
Humain
Réactivité croisée (Details)
Does not cross-react with human TRAIL-R1, -R3 or -R4.
Purification
Purified from concentrated hybridoma tissue culture supernatant.
Pureté
>95 % (SDS-PAGE)
Immunogène
Recombinant human TRAIL-R2 (DR5).
Clone
HS201
Isotype
IgG1
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Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
Lot specific
Buffer
In PBS containing 0.02 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Short Term Storage: +4°C Long Term Storage: -20°C Stable for at least 1 year after receipt when stored at -20°C.
Date de péremption
12 months
Détails sur TNFRSF10B
(cache)
Antigène
TNFRSF10B
(Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
Autre désignation
TRAIL-R2 (TNFRSF10B Produits )
Synonymes
anticorps TNFRSF10B, anticorps dr5, anticorps cd262, anticorps killer, anticorps trick2, anticorps trickb, anticorps xDR-M1, anticorps xDR-M2, anticorps ztnfr9, anticorps trailr2, anticorps trick2a, anticorps trick2b, anticorps CD262, anticorps DR5, anticorps KILLER, anticorps KILLER/DR5, anticorps TRAIL-R2, anticorps TRAILR2, anticorps TRICK2, anticorps TRICK2A, anticorps TRICK2B, anticorps TRICKB, anticorps ZTNFR9, anticorps Ly98, anticorps MK, anticorps tumor necrosis factor receptor superfamily, member 10b, anticorps tumor necrosis factor receptor superfamily member 10b S homeolog, anticorps tumor necrosis factor receptor superfamily member 10b L homeolog, anticorps tumor necrosis factor receptor superfamily member 10b, anticorps TNF receptor superfamily member 10b, anticorps Tnfrsf10b, anticorps TNFRSF10B, anticorps tnfrsf10b.S, anticorps tnfrsf10b.L, anticorps tnfrsf10b
Sujet
TRAIL-R2 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.
UniProt
O14763
Pathways
Signalisation p53 , Apoptose , Positive Regulation of Endopeptidase Activity
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