CTLA4 anticorps (PE)

N° du produit ABIN118892

Détail du produit anti-CTLA4 anticorps (PE)

Antigène: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CTLA4 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Specificité: This antibody recognises the CD152 cell surface antigen, also known as CTLA-4 (cytotoxic T-lymphocyteassociated antigen 4).

Purification: Affinity Chromatography

Immunogène: Human CTLA-4/human IgG heavy chain fusion protein. Spleen cells from immunised BALB/c mice were fused with cells of the mouse P3/X63-Ag8.653 myeloma cell line.

Clone: BNI3

Isotype: IgG2a

Information d'application

Indications d'application: Flow Cytometry: Use 20 μL of neat antibody to label 5x10e5 cells in 100 μL. Membrane permeabilisation is required for this application.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.09 % Sodium Azide as preservative and 0.2 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Dilute only prior to immediate use

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! Freezing alkaline phosphatase conjugates will result in a substantial loss of enzymatic activity.

Détails sur CTLA4

Antigène: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Autre désignation: CD152 / CTLA4 (CTLA4 Produits)

Synonymes: anticorps CTLA-4, anticorps CTLA4, anticorps CD152, anticorps Cd152, anticorps Ctla-4, anticorps Ly-56, anticorps CD, anticorps CELIAC3, anticorps GRD4, anticorps GSE, anticorps IDDM12, anticorps sCTLA4, anticorps cytotoxic T-lymphocyte associated protein 4, anticorps cytotoxic T-lymphocyte-associated protein 4, anticorps CTLA4, anticorps Ctla4

Sujet: CD152 is a 45kD glycoprotein, expressed normally as a disulphide-linked homodimer. It is expressed transiently on the surface of T cells following activation (peaking at 3 days), but is often present within the cytoplasm. CD152 is a ligand for CD80 and CD86, and is important in cellular interactions during the immune response.Synonyms: CTLA-4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4

ID gène: 1493

NCBI Accession: NP_001032720

UniProt: P16410

Pathways: Cancer Immune Checkpoints