WRNIP1 anticorps (Internal Region, Isoform 1, Isoform 2)

N° du produit ABIN129611

Détail du produit anti-WRNIP1 anticorps

Antigène: WRNIP1 (Werner Helicase Interacting Protein 1 (WRNIP1))

Épitope: Internal Region, Isoform 1, Isoform 2

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WRNIP1 est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée: Souris, Rat (Rattus), Singe

Attributs du produit: Concentration Definition: by UV absorbance at 280 nm

Immunogène: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an of the WHIP1 protein. The immunogen sequence shows 100% homology to human WHIP1 and WHIP2 with predicted molecular weights of 72.2 kDa and 69.5 kDa, respectively. The immunogen sequence also shows 100% homology to WHIP1 from mouse, rat and monkey sequences. Reactivity with WHIP proteins from other sources is not known, but is likely due to reported homologies.

Isotype: IgG

Information d'application

Indications d'application: This affinity purified antibody has been tested for use in western blotting against HEK293 whole cell lysates.  The antibody is also functional by ELISA.  Dilutions for western blotting represent a starting point dilution and further optimization may be required.  The antibody detects a band of approximately 96.0 kDa (predicted molecular weight: 72.2 kDa). Specific band detection by western blot is blocked by pre-incubating the antibody with the immunizing peptide prior to reaction with the membrane.  Reactivity in other immunoassays is unknown.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.10 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur WRNIP1

Antigène: WRNIP1 (Werner Helicase Interacting Protein 1 (WRNIP1))

Autre désignation: WHIP (WRNIP1 Produits)

Synonymes: anticorps WRNIP1, anticorps wrnip1, anticorps RP11-420G6.2, anticorps WHIP, anticorps bA420G6.2, anticorps zgc:85976, anticorps 4833444L21Rik, anticorps Wrnip, anticorps Whip, anticorps Werner helicase interacting protein 1, anticorps Werner helicase interacting protein 1 L homeolog, anticorps ATPase WRNIP1, anticorps WRNIP1, anticorps wrnip1.L, anticorps wrnip1, anticorps EDI_075920, anticorps CpipJ_CPIJ017857, anticorps PITG_07216, anticorps VDBG_02914, anticorps Wrnip1, anticorps PGTG_08805

Sujet: Werner's syndrome is a rare autosomal recessive disorder characterized by premature aging.  Werner helicase interacting protein 1 (WHIP) interacts with the N-terminal portion of Werner protein, which contains an exonuclease domain. This protein shows homology to replication factor C family proteins, and is conserved from E. coli to human. Studies in yeast suggest that this gene product may influence the aging process.  A second isoform exists (WHIP2).
Synonyms: ATPase WRNIP 1 antibody, ATPase WRNIP1 antibody, bA420G6.2 antibody, FLJ22526 antibody, Putative helicase RUVBL antibody, RP11 420G6.2 antibody, Werner helicasae interacting protein 1 antibody

ID gène: 56897, 55661735

UniProt: Q96S55