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CD40 anticorps

CD40 Reactivité: Souris FACS Hôte: Rat Monoclonal unconjugated

N° du produit ABIN133941

Fiche de données

Antigène Voir toutes CD40 Anticorps

CD40
Reactivité
192

110

22

20

7

6

4

4

4

4

2

2

2

2

2

1

1
Souris
Hôte
107

100

51

6

2

1

1

1
Rat
Anticorps secondaires appropriés
Clonalité
173

89

5
Monoclonal
Conjugué
124

24

21

19

12

8

7

4

4

4

4

3

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Cet anticorp CD40 est non-conjugé
Application
151

97

64

54

32

28

20

19

17

14

13

13

8

6

5

5

4

4

4

3

3

3

2

2

2

2

2

1

1

1

1
Flow Cytometry (FACS)

Specificité

Mouse CD40

Purification

Purified

Isotype

IgG2a

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anti-CD40 (CD40) (AA 26-187) antibody
CD40 Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated

anti-CD40 (CD40) antibody
CD40 Reactivité: Humain FACS, IHC, IF, StM, DNA Mic Hôte: Souris Monoclonal C40-1605 unconjugated

anti-CD40 (CD40) antibody
CD40 Reactivité: Humain WB, IHC, IF Hôte: Lapin Polyclonal unconjugated

anti-CD40 (CD40) (AA 21-193) antibody
CD40 Reactivité: Humain FACS, WB, ELISA, IHC, ICC, Neut Hôte: Souris Monoclonal 4E1B9 unconjugated

anti-CD40 (CD40) (AA 29-107) antibody
CD40 Reactivité: Humain FACS, ELISA, IHC, StM, Coat Hôte: Souris Monoclonal C40-2383 unconjugated

anti-CD40 (CD40) (C-Term) antibody
CD40 Reactivité: Humain, Souris, Rat WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated

anti-CD40 (CD40) (AA 71-187) antibody
CD40 Reactivité: Humain WB, IF Hôte: Souris Monoclonal 41-CD40 unconjugated

anti-CD40 (CD40) (Extracellular Domain) antibody
CD40 Reactivité: Humain FACS, IHC, St Hôte: Souris Monoclonal 5C3 unconjugated

anti-CD40 (CD40) (AA 1-360) antibody
CD40 Reactivité: Humain, Rat WB, IHC (p) Hôte: Lapin Polyclonal unconjugated

anti-CD40 (CD40) antibody (FITC)
CD40 Reactivité: Humain FACS Hôte: Souris Monoclonal HI40a FITC

Indications d'application

This antibody is suitable for use in flow cytometry.

Restrictions

For Research Use only
Concentration

0.2 mg/ml

Stock

4 °C
Antigène

CD40

Autre désignation

CD40 (CD40 Produits)

Synonymes

anticorps Bp50, anticorps CDW40, anticorps TNFRSF5, anticorps p50, anticorps AI326936, anticorps GP39, anticorps HIGM1, anticorps IGM, anticorps IMD3, anticorps T-BAM, anticorps TRAP, anticorps Tnfrsf5, anticorps TNFSF5, anticorps CD40 molecule, anticorps CD40 antigen, anticorps CD40, anticorps Cd40

Sujet

Anti-mouse monoclonal antibody reacts with CD40 which is expressed on B lymphocytes and on a subset of both CD4 and CD8 T cells in the adult (but not neonatal) spleen . The level of CD40 on B cells is enhanced following activation by LPS . The interactions of CD40 with its ligand CD40L are responsible for generating humoral responses, germinal centre formation, and generating B cell memory . Stimulating cells with immobilized 3/23 mAb increases expression of CD86(B7.2) on B cells 1,3 . Though the 3/23 mAb itself is a weak mitogen, it produces a synergistic proliferative B cell response with IL-4 or with mitogenic antibodies against surface Ig 1,3 . Costimulation with 3/23 mAb and IL-4 rescues B cells from apoptosis induced by hypercross-linking of sIgM or sIgD . Other applications of the 3/23 mAb include IHC of acetone-fixed frozen sections This antibody is suitable for use in flow cytometry.

Pathways

Signalisation NF-kappaB, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints