TRPM7 anticorps (AA 800-850)

N° du produit ABIN1387614

Détail du produit anti-TRPM7 anticorps

Antigène: TRPM7 (Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7))

Épitope: AA 800-850

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRPM7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TRPM7

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur TRPM7

Antigène: TRPM7 (Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7))

Autre désignation: TRPM7 (TRPM7 Produits)

Synonymes: anticorps cb495, anticorps TRPM7, anticorps chak, anticorps chak1, anticorps ltrpc7, anticorps trp-plik, anticorps ALSPDC, anticorps CHAK, anticorps CHAK1, anticorps LTRPC7, anticorps TRP-PLIK, anticorps 2310022G15Rik, anticorps 4833414K03Rik, anticorps 5033407O22Rik, anticorps LTrpC-7, anticorps Ltpr7, anticorps Ltrpc7, anticorps TRPPLIK, anticorps Chak, anticorps Trp-plik, anticorps transient receptor potential cation channel subfamily M member 7, anticorps transient receptor potential cation channel, subfamily M, member 7, anticorps TRPM7, anticorps trpm7, anticorps Trpm7

Sujet:

Synonyms: CHAK, CHAK1, ALSPDC, LTRPC7, LTrpC-7, TRP-PLIK, Transient receptor potential cation channel subfamily M member 7, Channel-kinase 1, Long transient receptor potential channel 7, TRPM7

Background: Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. Involved in TNF-induced necroptosis downstream of MLKL by mediating calcium influx. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1).

ID gène: 54822

UniProt: Q96QT4