APBA1 anticorps (AA 451-550) (Biotin)
-
- Antigène Voir toutes APBA1 Anticorps
- APBA1 (Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1))
-
Épitope
- AA 451-550
-
Reactivité
- Humain, Souris
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp APBA1 est conjugé à/à la Biotin
-
Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Réactivité croisée
- Humain, Souris
- Homologie
- Rat,Dog,Cow,Sheep,Pig,Chicken
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human APBA1
- Isotype
- IgG
- Top Product
- Discover our top product APBA1 Anticorps primaire
-
-
- Indications d'application
-
WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C for 12 months.
- Date de péremption
- 12 months
-
- Antigène
- APBA1 (Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1))
- Autre désignation
- APBA1 (APBA1 Produits)
- Synonymes
- anticorps APBA1, anticorps 6430513E09Rik, anticorps Lin-10, anticorps Mint, anticorps Mint1, anticorps Urop11, anticorps X11, anticorps X11alpha, anticorps D9S411E, anticorps LIN10, anticorps MINT1, anticorps X11A, anticorps X11ALPHA, anticorps amyloid beta precursor protein binding family A member 1, anticorps amyloid beta (A4) precursor protein-binding, family A, member 1b, anticorps ketopantoate reductase, anticorps 2-dehydropantoate 2-reductase, anticorps amyloid beta (A4) precursor protein-binding, family A, member 1 (X11), anticorps amyloid beta (A4) precursor protein-binding, family A, member 1, anticorps amyloid beta (A4) precursor protein binding, family A, member 1, anticorps APBA1, anticorps apba1b, anticorps apbA1, anticorps apba1, anticorps Apba1
- Sujet
-
Synonyms: Adapter protein X11 alpha; Adapter protein X11alpha; Amyloid beta A4 precursor protein-binding family A member 1; Apba1; APBA1_HUMAN; Mint 1; Mint-1; Neuron specic X11 protein; Neuron-specic X11 protein; Neuronal Munc18 1 interacting protein 1; Neuronal Munc18-1-interacting protein 1; UROP11; x11; X11alpha.
Background: The Beta-Amyloid precursor protein (Beta-APP) is a major constituent of the amyloid deposits in patients with Alzheimer?s disease. The Beta-Amyloid precursor is known to interact with several proteins, including X11 and the G heterotrimetric protein APP-BP1. The neuronal, transmembrane protein X11 is known to bind to the -Amyloid precursor protein via a phosphotyrosine binding (PTB) domain, reducing the secretion of cellular Beta-APP and slowing Beta-APP processing pathways. X11 binds specifically to the YENPTY motif, which is involved in the internalization of Beta-APP. Multiple splice varitents of X11 have been identified, including X11å (also designated Mint 1), X11Beta (Mint 2) and X11(Mint 3).
- Pathways
- Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
-