GNRHR2 anticorps (AA 81-180) (AbBy Fluor® 488)
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- Antigène Tous les produits GNRHR2
- GNRHR2 (Gonadotropin-Releasing Hormone (Type 2) Receptor 2 (GNRHR2))
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Épitope
- AA 81-180
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Reactivité
- Porc
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GNRHR2 est conjugé à/à la AbBy Fluor® 488
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Réactivité croisée
- Porc
- Homologie
- Human
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human GNRHR2
- Isotype
- IgG
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- GNRHR2 (Gonadotropin-Releasing Hormone (Type 2) Receptor 2 (GNRHR2))
- Autre désignation
- GNRHR2 (GNRHR2 Produits)
- Synonymes
- anticorps gnrhr1/iii, anticorps GnRH-II-R, anticorps gonadotropin releasing hormone receptor 2 (pseudogene), anticorps gonadotropin-releasing hormone (type 2) receptor 2, anticorps gnrhr2, anticorps GNRHR2
- Sujet
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Synonyms: GnRH IIR, Putative gonadotropin-releasing hormone II receptor, gonadotropin-releasing hormone type 2 receptor 2, GnRH-II-R, Type II GnRH receptor, GNRR2_HUMAN.
Background: Gonadotropin-releasing hormone (GnRH) is released in a pulsatile manner that varies with the reproductive cycle. This hypothalamic hormone is transported to the pituitary, where it binds to specific receptors and regulates the synthesis and release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Localized to the cell membrane, GnRHR2 mediates its own receptor activity via association with G proteins, thereby activating a phosphatidylinositol-calcium second messenger system that regulates GnRHR2 function. GnRHR2 is thought to have potent antiproliferative effects on ovarian and endometrial cancer cells, suggesting a possible role in tumor suppression. Due to alternative splicing events, GnRHR2 is expressed as two isoforms.
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