ALKBH1 anticorps (N-Term)

N° du produit ABIN1449917

Détail du produit anti-ALKBH1 anticorps

Antigène: ALKBH1 (AlkB, Alkylation Repair Homolog 1 (ALKBH1))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALKBH1 est non-conjugé

Application: Western Blotting (WB)

Séquence: PGFIFIPNPF LPGYQWHWVK QCLKLYSQKP NVCNLDKHMS KEETQDLWEQ

Réactivité croisée (Details): Species reactivity (expected):Bovine, Dog, MouseSpecies reactivity (tested):Human

Purification: Immunoaffinity column

Immunogène: Synthetic peptide corresponding to a N-terminal region of human ALKBH1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store lyophilized at 2-8 °C for one month or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Détails sur ALKBH1

Antigène: ALKBH1 (AlkB, Alkylation Repair Homolog 1 (ALKBH1))

Autre désignation: ALKBH1 (ALKBH1 Produits)

Synonymes: anticorps Alkbh, anticorps ABH, anticorps ABH1, anticorps ALKBH, anticorps alkB, anticorps hABH, anticorps 2700073G19Rik, anticorps Abh, anticorps alkB homolog 1, histone H2A dioxygenase, anticorps Alkbh1, anticorps ALKBH1

Sujet: ALKBH1 is a dioxygenase that repairs alkylated single-stranded DNA and RNA containing 3-methylcytosine by oxidative demethylation. This requires molecular oxygen, alpha-ketoglutarate and iron. ALKBH1 may have a role in placental trophoblast lineage differentiation, has DNA lyase activity and introduces double-stranded breaks at abasic sites. It cleaves both single-stranded DNA and double-stranded DNA at abasic sites, with the greatest activity towards double-stranded DNA with two abasic sites. DNA lyase activity does not require alpha-ketoglutarate and iron.Synonyms: ABH, ALKBH, Alkylated DNA repair protein alkB homolog 1

Poids moléculaire: ALX1: 37 kDa

ID gène: 8846

NCBI Accession: NP_006011

Pathways: Réparation de l'ADN