ARFGAP1 anticorps (AA 171-220)
Aperçu rapide pour ARFGAP1 anticorps (AA 171-220) (ABIN1534608)
Antigène
Voir toutes ARFGAP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 171-220
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Fonction
- ARF GAP1 Antibody
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Specificité
- ARF GAP1 Polyclonal Antibody detects endogenous levels of ARF GAP1 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human ARFGAP1. AA range:171-220
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))
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Autre désignation
- ARFGAP1
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Sujet
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Synonyms: ARFGAP1, ARF1GAP, ADP-ribosylation factor GTPase-activating protein 1, ARF GAP 1, ADP-ribosylation factor 1 GTPase-activating protein, ARF1 GAP, ARF1-directed GTPase-activating protein
Background: The protein encoded by this gene is a GTPase-activating protein, which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
Gene Name: ARFGAP1
Protein Name: ADP-ribosylation factor GTPase-activating protein 1
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Poids moléculaire
- 44 kDa
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ID gène
- 55738
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OMIM
- 608377
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UniProt
- Q8N6T3
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Pathways
- Signalisation p53, ER-Nucleus Signaling, Unfolded Protein Response
Antigène
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