SUV39H2 anticorps (C-Term)

N° du produit ABIN1537206

Détail du produit anti-SUV39H2 anticorps

Antigène: SUV39H2 (Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2))

Épitope: AA 367-395, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SUV39H2 est non-conjugé

Application: Western Blotting (WB)

Homologie: Pr, M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This SUV39H2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 367-395 amino acids from the C-terminal region of human SUV39H2.

Clone: RB40398

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: SUV39H2 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur SUV39H2

Antigène: SUV39H2 (Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2))

Autre désignation: SUV39H2 (SUV39H2 Produits)

Synonymes: anticorps KMT1B, anticorps 4930507K23Rik, anticorps AA536750, anticorps D030054H19Rik, anticorps D2Ertd544e, anticorps SUV39H2, anticorps kmt1b, anticorps suppressor of variegation 3-9 homolog 2, anticorps suppressor of variegation 3-9 homolog 2 (Drosophila), anticorps suppressor of variegation 3-9 homolog 2 L homeolog, anticorps SUV39H2, anticorps Suv39h2, anticorps suv39h2, anticorps suv39h2.L

Sujet: Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats. SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes, such as cell cycle regulation, transcriptional repression and regulation of telomere length. May participate in regulation of higher order chromatin organization during spermatogenesis.

Poids moléculaire: 46682

ID gène: 79723

NCBI Accession: NP_001180353, NP_001180354, NP_001180355, NP_001180356, NP_078946

UniProt: Q9H5I1