NR1H3 anticorps
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- Antigène Voir toutes NR1H3 Anticorps
- NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp NR1H3 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Réactivité croisée
- Humain, Souris, Rat
- Attributs du produit
- Monoclonal Antibodies
- Purification
- Affinity purification
- Immunogène
- A synthesized peptide derived from human LXRalpha
- Isotype
- IgG
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- Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
- Autre désignation
- NR1H3 (NR1H3 Produits)
- Synonymes
- anticorps NR1H3, anticorps LXR-a, anticorps LXRA, anticorps RLD-1, anticorps AU018371, anticorps LXR, anticorps RLD1, anticorps Unr1, anticorps LXRalpha, anticorps LXR-alpha, anticorps im:7141239, anticorps wu:fd59b01, anticorps zgc:113339, anticorps zgc:158542, anticorps nuclear receptor subfamily 1 group H member 3, anticorps nuclear receptor subfamily 1, group H, member 3, anticorps NR1H3, anticorps nr1h3, anticorps Nr1h3
- Sujet
- The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],LXR-a, LXRA, RLD-1,Cancer,Cardiovascular,Endocrine & Metabolism,Epigenetics & Nuclear Signaling,Lipid Metabolism,Lipid Metabolism_Cholesterol Metabolism,Lipids,Nuclear Receptor Signaling,Signal Transduction,Transcription Factors,NR1H3
- Poids moléculaire
- 50 kDa
- ID gène
- 10062
- UniProt
- Q13133
- Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding, Cellular Response to Molecule of Bacterial Origin, Hepatitis C
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