CYP11B2 anticorps (AA 234-503)

N° du produit ABIN1679468

Détail du produit anti-CYP11B2 anticorps

Antigène: CYP11B2 (Cytochrome P450, Family 11, Subfamily B, Polypeptide 2 (CYP11B2))

Épitope: AA 234-503

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP11B2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: TVQLMFMPRS LSRWISPKVW KEHFEAWDCI FQYGDNCIQK IYQELAFNRP QHYTGIVAEL LLKAELSLEA IKANSMELTA GSVDTTAFPL LMTLFELARN PDVQQILRQE SLAAAASISE HPQKATTELP LLRAALKETL RLYPVGLFLE RVVSSDLVLQ NYHIPAGTLV QVFLYSLGRN AALFPRPERY NPQRWLDIRG SGRNFHHVPF GFGMRQCLGR RLAEAEMLLL LHHVLKHFLV ETLTQEDIKM VYSFILRPGT SPLLTFRAIN

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 234-503 of human CYP11B2 (NP_000489.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:1000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CYP11B2

Antigène: CYP11B2 (Cytochrome P450, Family 11, Subfamily B, Polypeptide 2 (CYP11B2))

Autre désignation: CYP11B2 (CYP11B2 Produits)

Synonymes: anticorps ALDOS, anticorps CPN2, anticorps CYP11B, anticorps CYP11BL, anticorps CYPXIB2, anticorps P-450C18, anticorps P450C18, anticorps P450aldo, anticorps Cpn2, anticorps Cyp11b, anticorps Cyp11b-2, anticorps Cp45as, anticorps Cyp11b3, anticorps RNCP45AS, anticorps cytochrome P450 family 11 subfamily B member 2, anticorps cytochrome P450, family 11, subfamily b, polypeptide 2, anticorps aldosterone synthase, anticorps cytochrome P450, family 11, subfamily B, polypeptide 2, anticorps cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 2, anticorps CYP11B2, anticorps Cyp11b2

Sujet: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency.,CYP11B2,ALDOS,CPN2,CYP11B,CYP11BL,CYPXIB2,P-450C18,P450C18,P450aldo,CYP11B2

Poids moléculaire: 57 kDa

ID gène: 1585

UniProt: P19099

Pathways: ACE Inhibitor Pathway, Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones, C21-Steroid Hormone Metabolic Process, Feeding Behaviour